This document summarizes a study that aimed to evaluate preoperative clinical and ultrasonographic factors that can predict difficult laparoscopic cholecystectomies. The study prospectively analyzed 105 patients undergoing laparoscopic cholecystectomy between May 2017 and January 2019. Several preoperative variables were analyzed including age, BMI, previous abdominal surgery, gallbladder wall thickness on ultrasound, and number and size of gallstones. The study found that difficulty accessing the peritoneal cavity was associated with obesity and previous abdominal surgery. Bleeding during surgery was associated with previous upper abdominal surgery, thickened gallbladder wall, and history of acute cholecystitis. Difficult gallbladder bed dissection was seen in those with prior cholecystitis