Diabetes doesn't just effect our systemic health but also affects the oral cavity which is of significance in oral hygiene maintenance, incidence, treatment planning and prognosis of the disease.
3. ORAL MANIFESTATIONS
OF DIABETES
DENTAL
CARIES AND
TOOTH LOSS
FUNGAL
INFECTIONS
BACTERIAL
INFECTION
GEOGRAPHI
C TONGUE
FISSURED
TONGUE
ORAL
MUCOSAL
DISEASE
PERIODONT
AL DISEASES
SALIVARY
DYSFUNCTI
ON
DELAYED
MUCOSAL
WOUND
HEALING
4. PERIODONTAL DISEASES
• It is a chronic inflammatory disease affecting
gingiva and periodontal tissues initiated by
bacteria.
MICROFLORA IN
DENTAL PLAQUE
ACCUMULATED DAILY
GINGGIVAL
INFLAMMATION
DESTRUCTION OF
PERIODONTIAL TISSUES
AND ALVEOLAR BONE
PERIODONTAL POCKET
IS FILLED WITH
BACTERIA AND TOINS
DEEPER POCKET
REACHING ALVEOLAR
BONE
TOOTH LOSS
5. Diabetes associated factors that
increase Periodontal disease
• Periodontal flora in diabetes patients composed mainly of –
Capnocytophaga, Anaerobic Vibrios, and Actinomyces
species
• Increased glucose level in crevicular fluid
• Defect in host response – Neutrophil impairement,
decreased chemotais, phagocytosis and intracellular
bacterial activity.
• Vascular changes – basement membrane protein
undergoes non-enzymatic glycosylation in hyperglycemic
condition.
• Decreased wound healing – decrease in collagen
production due to glycosylation of collagen and other
proteins.
6. SALIVARY AND TASTE DYSFUNCTION
• Type I – reduced salivary flow rate and
×erostomia (dry mouth), especially those with
neuropathy.
• Type II – reduced salivary flow rate and
erostomia with lower stimulated parotid gland
flow rate in patients with poor control.
• Polydypsia and polyuria.
CONSTANT
DRYNESS
INFECTION
INFLAMMATION
DECAY
IRRITATE THE
ORAL MUCOSA
UNCONTROLLED
DIADETES
SALIVARY
DYSFUNCTION
ELEVATION OF
DETECTION
THRESHOLDS (taste)
7. FUNGAL INFECTIONS
• Oral candidosis is an opportunistic infection
frequently cased by Candida albicans.
• Predisposing factors along with diabetes –
smoking, ×erostomia, old age, medications,
Cushing’s syndrome, malignancies and the use
of dentures.
• Colonisation in diabetes patients – 75% and
controls – 35.1%
8. BACTERIAL INFECTIONS
• Impaired defense mechanism
• Submandibular space infection
was more common followed by buccal space
infection.
• Stay longer in hospital due to more severe
infection and required more time to control
their blood glucose. SUSCEPTIBLE
*POOR CONTROL
*DIABETIC
COMPLICATIONS
9. DELAYED WOUND HEALING
• Poor soft tissue regeneration and delayed
osseous healing. (complication during oral
surgery)
• Delayed vascularisation, reduced blood flow, a
decline in innate immunity, decreased growth
factor production and psychological stress
may be involved.
10. ORAL MUCOSAL DISEASE
• Oral lichen planus (OLP) is a skin disorder that produce
lesions in the mouth. More common in type I.
Type I is also an autoimmune disease.
Patients with diabetes prolonged state of chronic
immune suppression.
Acute hyperglycaemia alterations in immune
response
• Atrophic-erosive oral lesions – common in diabetes +
OLP
REASONS
11. DENTAL CARIES AND TOOTH LOSS
• Cleansing and buffering capacity of the saliva
is diminished in patients resulting in increased
caries, especially in those with ×erostomia.
• The relationship between diabetes and
development of dental caries is still unclear.