Desensitization alters signaling pathways to become less responsive to persistent signaling. For example, when you are inside a darker location, your eyes become "tuned" to the darkness. However, when you step back out into bright sunlight, you can clearly detect the drastic increase in light. This is because desensitized signaling pathways are: Not involved in detecting new signals Capable of detecting changes in signal Capable of detecting decreased signal Capable of detecting increased signal Cell signaling pathways often include mechanisms that can amplify the impact of the signal. Which of the following is NOT a mechanism of amplification? Positive feedback loops that increase the activation of upstream signaling molecules Production of second messengers within the cell Cell division to produce more cells that can generate signal Activation of multiple enzymes by a signal activated receptor.