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Cranial Nerves
Cranial nerves are spinal nerves that originate
from the brain instead of the spinal cord and
come out of the encasement through cranial
foramina instead of intervertebral foramina
Cranial Nerves
Cranial nerves are spinal nerves that originate
from the brain instead of the spinal cord and
come out of the brain through cranial foramina
instead of intervertebral foramina.
They can serve either a sensory, motor or mixed
(both) functions.
Olfactory
Optic
Oculomotor
Trochlear
Trigeminal
Abducens
Vestibulocochlear
Glossopharyngeal
Vagus
Accessory Hypoglossal
Facial
Copyright © 2010 Pearson Education, Inc.
Frontal lobe
Temporal lobe
Infundibulum
Facial
nerve (VII)
Vestibulo-
cochlear
nerve (VIII)
Glossopharyngeal
nerve (IX)
Vagus nerve (X)
Accessory nerve (XI)
Hypoglossal nerve (XII)
(a)
Filaments of
olfactory
nerve (I)
Olfactory bulb
Olfactory tract
Optic chiasma
Optic nerve
(II)
Optic tract
Oculomotor
nerve (III)
Trochlear
nerve (IV)
Trigeminal
nerve (V)
Abducens
nerve (VI)
Cerebellum
Medulla
oblongata
Classification of cranial nerves
• Sensory cranial nerves: contain only afferent (sensory) fibers
– Ⅰ Olfactory nerve
– Ⅱ Optic nerve
– Ⅷ Vestibulocochlear nerve
• Motor cranial nerves: contain only efferent (motor) fibers
– Ⅲ Oculomotor nerve
– Ⅳ Trochlear nerve
– Ⅵ Abducent nerve
– Ⅺ Accessory nerv
– Ⅻ Hypoglossal nerve
• Mixed nerves: contain both sensory and motor fibers---
– Ⅴ Trigeminal nerve,
– Ⅶ Facial nerve,
– Ⅸ Glossopharyngeal nerve
– Ⅹ Vagus nerve
Function
Cranial Nerve I: Olfactory
• Arises from the olfactory epithelium
• Passes through the cribriform plate of the
ethmoid bone
• Fibers run through the olfactory bulb and
terminate in the primary olfactory cortex
• Functions solely by carrying afferent impulses
for the sense of smell
S
Cranial Nerve I: Olfactory
Figure I from Table 13.2
Cranial Nerve II: Optic
• Arises from the visual cortex of the cerebrum
• Optic nerves pass through the optic canals and
converge at the optic chiasm
• They continue to the thalamus where they synapse
• From there, the optic radiation fibers run to the
retina of the eye
• Functions solely by carrying afferent impulses for
vision
S
Cranial Nerve II: Optic
Figure II Table 13.2
Cranial Nerve III: Oculomotor
• Fibers extend from the ventral midbrain, pass
through the superior orbital fissure, and go to the
extrinsic eye muscles
• Functions in raising the eyelid, directing the eyeball,
constricting the iris, and controlling lens shape
• The latter 2 functions are parasympathetically
controlled
• Parasympathetic cell bodies are in the ciliary ganglia
M
Cranial Nerve III: Oculomotor
Figure III from Table 13.2
Ocularmotor paralysis
Cranial Nerve IV: Trochlear
• Fibers emerge from the dorsal midbrain and
enter the orbits via the superior orbital
fissures; innervate the superior oblique
muscle
• Primarily a motor nerve that directs the
eyeball
M
Cranial Nerve IV: Trochlear
Figure IV from Table 13.2
Cranial Nerve V: Trigeminal
• Composed of three divisions: ophthalmic
(V1), maxillary (V2), and mandibular (V3)
• Conveys sensory impulses from various
areas of the face (V1) and (V2), and supplies
motor fibers (V3) for mastication
• These (sensory & motor) Fibers run from
the face to the pons via the superior orbital
fissure (V1), the foramen rotundum (V2),
and the foramen ovale (V3)
B
Cranial Nerve V: Trigeminal
Cranial Nerve VI: Abducens
• Fibers leave the inferior pons and enter the orbit
via the superior orbital fissure
• Primarily a motor nerve innervating the lateral
rectus muscle (abducts the eye; thus the name
abducens)
Figure VI from Table 13.2
M
Abducens nerve injury
Cranial Nerve VII: Facial
• Fibers leave the pons, travel through the
internal acoustic meatus, and emerge
through the stylomastoid foramen to the
lateral aspect of the face
• Motor functions include facial expression,
and the transmittal of autonomic impulses
to lacrimal and salivary glands
• Sensory function is taste from the anterior
two-thirds of the tongue
B
Cranial Nerve VII: Facial
Figure VII from Table 13.2
Facial nerve injury +/- Bells Palsy
Cranial Nerve VIII: Vestibulocochlear
• Fibers arise from the hearing and equilibrium
apparatus of the inner ear, pass through the internal
acoustic meatus, and enter the brainstem at the
pons-medulla border
• Two divisions – cochlear (hearing) and vestibular
(balance)
• Functions are solely sensory – equilibrium and
hearing
S
Cranial Nerve VIII: Vestibulocochlear
Figure VIII from Table 13.2
Cranial Nerve IX: Glossopharyngeal
• Fibers emerge from the medulla, leave the skull via
the jugular foramen, and run to the throat
• Nerve IX is a mixed nerve with motor and sensory
functions
• Motor – innervates part of the tongue and pharynx,
and provides motor fibers to the parotid salivary
gland
• Sensory – fibers conduct taste and general sensory
impulses from the tongue and pharynx
B
Cranial Nerve IX: Glossopharyngeal
Figure IX from Table 13.2
Cranial Nerve X: Vagus
• The only cranial nerve that extends beyond the head
and neck
• Fibers emerge from the medulla via the jugular
foramen
• The vagus is a mixed nerve
• Most motor fibers are parasympathetic fibers to the
heart, lungs, and visceral organs
• Its sensory function is in taste
B
Cranial Nerve X: Vagus
Cranial Nerve XI: Accessory
• Formed from a cranial root emerging from the
medulla and a spinal root arising from the
superior region of the spinal cord
• The spinal root passes upward into the
cranium via the foramen magnum
• The accessory nerve leaves the cranium via
the jugular foramen
M
Cranial Nerve XI: Accessory
• Primarily a motor nerve
– Supplies fibers to the larynx, pharynx, and soft
palate
– Innervates the trapezius and sternocleidomastoid,
which move the head and neck
Cranial Nerve XI: Accessory
Cranial Nerve XII: Hypoglossal
• Fibers arise from the medulla and exit the
skull via the hypoglossal canal
• Innervates both extrinsic and intrinsic
muscles of the tongue, which contribute to
swallowing and speech
M
Cranial Nerve XII: Hypoglossal
Figure XII from Table 13.2
Mnemonics
There are a variety of mnemonics that help you
remember the cranial nerves.
For number in order
“On occasion, our tiny truck acts funny, very good
vehicle anyhow”
For Function
“Some say marry money but my brother says bigger
brains matter more”
Functions (modalities) of the Cranial nerves
Each cranial nerve can be described as being
sensory, motor or both.
They can more specifically transmit seven types of
information;
Three of these types of information are unique to
cranial nerves (SSS, SVS and SVM).
Sensory (afferent) Modalities:
• General somatic sensory (GSS) – general sensation
from skin.
• General visceral sensory (GVS) – general sensation
from viscera.
• Special somatic sensory (SSS) – senses derived from
ectoderm (e.g. sight, sound, balance).
• Special visceral sensory (SVS) – senses derived from
endoderm (e.g. taste, smell).
Motor (efferent) Modalities:
• General somatic motor (GSM) – skeletal muscles.
• General visceral motor (GVM) – smooth muscles
of gut and autonomic motor.
• Special visceral motor (SVM) – muscles derived
from pharyngeal arches.
Summary of Function of Cranial
Nerves
Examination of Cranial Nerve Function
Each cranial nerve carries out specific functions.
Testing for a deficiency of a cranial nerves'
function can give a radiographer an idea of
where the problem is located in a person’s brain.
Cont…
Necessary to know the most frequent
pathologies that may involve cranial nerves and
recognize their typical characteristics of imaging.
Cranial nerve dysfunctions may be the result of
pathological processes of the cranial nerve itself
or be related to tumors, inflammation,
infectious processes, or traumatic injuries of
adjacent structures.
Common Cranial Nerve Conditions
 Bells Palsy
 Trigeminal Neuralgia
 Acoustic Neuroma
 Vertigo and Dizziness
 Conjugate Gaze Palsies
 Glossopharyngeal Neuralgia
 Hemifacial Spasm
 Hypoglossal Nerve Disorder
 Facial Nerve
 Meniere Disease
Common Cranial Nerve Conditions
Bell’s Palsy results from damage to the seventh
cranial nerve or facial nerve.
Bell's palsy is characterized by a one sided facial
droop that comes on within 72 hours
Trigeminal neuralgia is a condition involving
intense pain in the area innervated by the
Trigeminal or fifth cranial nerve.
Neural Imaging
-Visualization of cranial nerves in routine clinical
practice can be challenging as most are quite small
and difficult to resolve.
-Intracranially, the cisternal (as they pass from the
brain to their respective foramina) portion is most
readily appreciated as the nerves are surrounded
by CSF.
Neural Imaging
As the nerves exit the skull, their location can be
implied by knowledge of normal anatomy but, due
to the complicated anatomy of the base of the skull
and head and neck, actually visualizing these small
structures is challenging on all modalities.
Neural Imaging
MRI - considered the gold standard in the study of
the cranial nerves.
CT – only allows, usually, an indirect view of the
nerve and is useful to demonstrate the
intraosseous segments of cranial nerves
(intraforamina segment) thru which they exit skull
base and their pathologic changes.
Large trigerminal schwannoma

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Cranial nerves - esson presentation.pptx

  • 1. Cranial Nerves Cranial nerves are spinal nerves that originate from the brain instead of the spinal cord and come out of the encasement through cranial foramina instead of intervertebral foramina
  • 2. Cranial Nerves Cranial nerves are spinal nerves that originate from the brain instead of the spinal cord and come out of the brain through cranial foramina instead of intervertebral foramina. They can serve either a sensory, motor or mixed (both) functions.
  • 4. Copyright © 2010 Pearson Education, Inc. Frontal lobe Temporal lobe Infundibulum Facial nerve (VII) Vestibulo- cochlear nerve (VIII) Glossopharyngeal nerve (IX) Vagus nerve (X) Accessory nerve (XI) Hypoglossal nerve (XII) (a) Filaments of olfactory nerve (I) Olfactory bulb Olfactory tract Optic chiasma Optic nerve (II) Optic tract Oculomotor nerve (III) Trochlear nerve (IV) Trigeminal nerve (V) Abducens nerve (VI) Cerebellum Medulla oblongata
  • 5. Classification of cranial nerves • Sensory cranial nerves: contain only afferent (sensory) fibers – Ⅰ Olfactory nerve – Ⅱ Optic nerve – Ⅷ Vestibulocochlear nerve • Motor cranial nerves: contain only efferent (motor) fibers – Ⅲ Oculomotor nerve – Ⅳ Trochlear nerve – Ⅵ Abducent nerve – Ⅺ Accessory nerv – Ⅻ Hypoglossal nerve • Mixed nerves: contain both sensory and motor fibers--- – Ⅴ Trigeminal nerve, – Ⅶ Facial nerve, – Ⅸ Glossopharyngeal nerve – Ⅹ Vagus nerve
  • 7. Cranial Nerve I: Olfactory • Arises from the olfactory epithelium • Passes through the cribriform plate of the ethmoid bone • Fibers run through the olfactory bulb and terminate in the primary olfactory cortex • Functions solely by carrying afferent impulses for the sense of smell S
  • 8. Cranial Nerve I: Olfactory Figure I from Table 13.2
  • 9. Cranial Nerve II: Optic • Arises from the visual cortex of the cerebrum • Optic nerves pass through the optic canals and converge at the optic chiasm • They continue to the thalamus where they synapse • From there, the optic radiation fibers run to the retina of the eye • Functions solely by carrying afferent impulses for vision S
  • 10. Cranial Nerve II: Optic Figure II Table 13.2
  • 11. Cranial Nerve III: Oculomotor • Fibers extend from the ventral midbrain, pass through the superior orbital fissure, and go to the extrinsic eye muscles • Functions in raising the eyelid, directing the eyeball, constricting the iris, and controlling lens shape • The latter 2 functions are parasympathetically controlled • Parasympathetic cell bodies are in the ciliary ganglia M
  • 12. Cranial Nerve III: Oculomotor Figure III from Table 13.2
  • 14. Cranial Nerve IV: Trochlear • Fibers emerge from the dorsal midbrain and enter the orbits via the superior orbital fissures; innervate the superior oblique muscle • Primarily a motor nerve that directs the eyeball M
  • 15. Cranial Nerve IV: Trochlear Figure IV from Table 13.2
  • 16. Cranial Nerve V: Trigeminal • Composed of three divisions: ophthalmic (V1), maxillary (V2), and mandibular (V3) • Conveys sensory impulses from various areas of the face (V1) and (V2), and supplies motor fibers (V3) for mastication • These (sensory & motor) Fibers run from the face to the pons via the superior orbital fissure (V1), the foramen rotundum (V2), and the foramen ovale (V3) B
  • 17. Cranial Nerve V: Trigeminal
  • 18. Cranial Nerve VI: Abducens • Fibers leave the inferior pons and enter the orbit via the superior orbital fissure • Primarily a motor nerve innervating the lateral rectus muscle (abducts the eye; thus the name abducens) Figure VI from Table 13.2 M
  • 20. Cranial Nerve VII: Facial • Fibers leave the pons, travel through the internal acoustic meatus, and emerge through the stylomastoid foramen to the lateral aspect of the face • Motor functions include facial expression, and the transmittal of autonomic impulses to lacrimal and salivary glands • Sensory function is taste from the anterior two-thirds of the tongue B
  • 21. Cranial Nerve VII: Facial Figure VII from Table 13.2
  • 22. Facial nerve injury +/- Bells Palsy
  • 23. Cranial Nerve VIII: Vestibulocochlear • Fibers arise from the hearing and equilibrium apparatus of the inner ear, pass through the internal acoustic meatus, and enter the brainstem at the pons-medulla border • Two divisions – cochlear (hearing) and vestibular (balance) • Functions are solely sensory – equilibrium and hearing S
  • 24. Cranial Nerve VIII: Vestibulocochlear Figure VIII from Table 13.2
  • 25. Cranial Nerve IX: Glossopharyngeal • Fibers emerge from the medulla, leave the skull via the jugular foramen, and run to the throat • Nerve IX is a mixed nerve with motor and sensory functions • Motor – innervates part of the tongue and pharynx, and provides motor fibers to the parotid salivary gland • Sensory – fibers conduct taste and general sensory impulses from the tongue and pharynx B
  • 26. Cranial Nerve IX: Glossopharyngeal Figure IX from Table 13.2
  • 27. Cranial Nerve X: Vagus • The only cranial nerve that extends beyond the head and neck • Fibers emerge from the medulla via the jugular foramen • The vagus is a mixed nerve • Most motor fibers are parasympathetic fibers to the heart, lungs, and visceral organs • Its sensory function is in taste B
  • 29. Cranial Nerve XI: Accessory • Formed from a cranial root emerging from the medulla and a spinal root arising from the superior region of the spinal cord • The spinal root passes upward into the cranium via the foramen magnum • The accessory nerve leaves the cranium via the jugular foramen M
  • 30. Cranial Nerve XI: Accessory • Primarily a motor nerve – Supplies fibers to the larynx, pharynx, and soft palate – Innervates the trapezius and sternocleidomastoid, which move the head and neck
  • 31. Cranial Nerve XI: Accessory
  • 32. Cranial Nerve XII: Hypoglossal • Fibers arise from the medulla and exit the skull via the hypoglossal canal • Innervates both extrinsic and intrinsic muscles of the tongue, which contribute to swallowing and speech M
  • 33. Cranial Nerve XII: Hypoglossal Figure XII from Table 13.2
  • 34. Mnemonics There are a variety of mnemonics that help you remember the cranial nerves. For number in order “On occasion, our tiny truck acts funny, very good vehicle anyhow” For Function “Some say marry money but my brother says bigger brains matter more”
  • 35.
  • 36. Functions (modalities) of the Cranial nerves Each cranial nerve can be described as being sensory, motor or both. They can more specifically transmit seven types of information; Three of these types of information are unique to cranial nerves (SSS, SVS and SVM).
  • 37. Sensory (afferent) Modalities: • General somatic sensory (GSS) – general sensation from skin. • General visceral sensory (GVS) – general sensation from viscera. • Special somatic sensory (SSS) – senses derived from ectoderm (e.g. sight, sound, balance). • Special visceral sensory (SVS) – senses derived from endoderm (e.g. taste, smell).
  • 38. Motor (efferent) Modalities: • General somatic motor (GSM) – skeletal muscles. • General visceral motor (GVM) – smooth muscles of gut and autonomic motor. • Special visceral motor (SVM) – muscles derived from pharyngeal arches.
  • 39. Summary of Function of Cranial Nerves
  • 40. Examination of Cranial Nerve Function Each cranial nerve carries out specific functions. Testing for a deficiency of a cranial nerves' function can give a radiographer an idea of where the problem is located in a person’s brain.
  • 41. Cont… Necessary to know the most frequent pathologies that may involve cranial nerves and recognize their typical characteristics of imaging. Cranial nerve dysfunctions may be the result of pathological processes of the cranial nerve itself or be related to tumors, inflammation, infectious processes, or traumatic injuries of adjacent structures.
  • 42. Common Cranial Nerve Conditions  Bells Palsy  Trigeminal Neuralgia  Acoustic Neuroma  Vertigo and Dizziness  Conjugate Gaze Palsies  Glossopharyngeal Neuralgia  Hemifacial Spasm  Hypoglossal Nerve Disorder  Facial Nerve  Meniere Disease
  • 43. Common Cranial Nerve Conditions Bell’s Palsy results from damage to the seventh cranial nerve or facial nerve. Bell's palsy is characterized by a one sided facial droop that comes on within 72 hours Trigeminal neuralgia is a condition involving intense pain in the area innervated by the Trigeminal or fifth cranial nerve.
  • 44. Neural Imaging -Visualization of cranial nerves in routine clinical practice can be challenging as most are quite small and difficult to resolve. -Intracranially, the cisternal (as they pass from the brain to their respective foramina) portion is most readily appreciated as the nerves are surrounded by CSF.
  • 45. Neural Imaging As the nerves exit the skull, their location can be implied by knowledge of normal anatomy but, due to the complicated anatomy of the base of the skull and head and neck, actually visualizing these small structures is challenging on all modalities.
  • 46. Neural Imaging MRI - considered the gold standard in the study of the cranial nerves. CT – only allows, usually, an indirect view of the nerve and is useful to demonstrate the intraosseous segments of cranial nerves (intraforamina segment) thru which they exit skull base and their pathologic changes.