This document summarizes a study on eHealthMe about reports of constipation as a side effect of taking Clonidine hydrochloride. The study found that of 724 people who reported side effects from Clonidine hydrochloride, 32 people (4.42%) reported experiencing constipation. It provides details on the time taking the drug, gender, age, severity, and recovery of those who experienced constipation as a side effect. It also lists common conditions and co-used drugs for these patients and invites users to comment or check if constipation could be from a condition rather than the drug.
El documento describe problemas técnicos que el autor ha tenido con su cuenta de Facebook, incluyendo que su cuenta fue desactivada sin explicación, que ha intentado descargar su información de la cuenta durante meses sin éxito, y que cree que alguien está accediendo a su cuenta de forma maliciosa.
Traveling or touring or going for excursions needs some preparations. A traveler should go through the news bulletins and weather forecasting of that place. Be net savvy for checking out the fares or hotels, transports and restaurants. Never forget to keep the photocopies of the essential document alongside originals. First-aid box, flashlight and umbrella can take the travelers out of any odd situation.
Egemin built a new highly automated production plant for Laboratoria Smeets by refurbishing an existing building and reinstalling a process installation they had purchased. Egemin took on the EPCM role, handling all engineering, procurement, construction, and management of the complex project. They automated processes, improved ergonomics for employees, and added innovations like increased heating capacity and closed circuit solvent regeneration. The new plant allows Laboratoria Smeets to increase competitiveness through improved functionality, documentation, maintenance costs, and process monitoring.
Las secuencias didácticas son sucesiones de actividades interrelacionadas diseñadas para guiar los procesos de enseñanza y aprendizaje. Se componen de tres etapas: apertura, desarrollo y cierre. Su objetivo es ayudar a los docentes a planificar de manera secuencial los contenidos, actividades y evaluación de acuerdo con los objetivos educativos y las características de los estudiantes.
GreenPowerMonitor is a company that manages and monitors renewable energy plants globally, with over 2GW managed across more than 1,500 plants. They provide an integrated hardware, software, and services solution for asset management, control, and maintenance of renewable power facilities, including recently being commissioned to monitor and manage a 266MW solar farm.
Govert Cornelis van Drimmelen has worked as a Business Manager at Capitec Bank since 2007 and previously worked at Coca-Cola Fortune and ABI Coca-Cola in various management roles. He received an MBA from Tshwane University of Technology in 2010 and served in the South African Defence Force from 1989-1990. He is seeking new opportunities in business management with over 20 years of experience in sales, marketing, operations, and people management.
El documento describe problemas técnicos que el autor ha tenido con su cuenta de Facebook, incluyendo que su cuenta fue desactivada sin explicación, que ha intentado descargar su información de la cuenta durante meses sin éxito, y que cree que alguien está accediendo a su cuenta de forma maliciosa.
Traveling or touring or going for excursions needs some preparations. A traveler should go through the news bulletins and weather forecasting of that place. Be net savvy for checking out the fares or hotels, transports and restaurants. Never forget to keep the photocopies of the essential document alongside originals. First-aid box, flashlight and umbrella can take the travelers out of any odd situation.
Egemin built a new highly automated production plant for Laboratoria Smeets by refurbishing an existing building and reinstalling a process installation they had purchased. Egemin took on the EPCM role, handling all engineering, procurement, construction, and management of the complex project. They automated processes, improved ergonomics for employees, and added innovations like increased heating capacity and closed circuit solvent regeneration. The new plant allows Laboratoria Smeets to increase competitiveness through improved functionality, documentation, maintenance costs, and process monitoring.
Las secuencias didácticas son sucesiones de actividades interrelacionadas diseñadas para guiar los procesos de enseñanza y aprendizaje. Se componen de tres etapas: apertura, desarrollo y cierre. Su objetivo es ayudar a los docentes a planificar de manera secuencial los contenidos, actividades y evaluación de acuerdo con los objetivos educativos y las características de los estudiantes.
GreenPowerMonitor is a company that manages and monitors renewable energy plants globally, with over 2GW managed across more than 1,500 plants. They provide an integrated hardware, software, and services solution for asset management, control, and maintenance of renewable power facilities, including recently being commissioned to monitor and manage a 266MW solar farm.
Govert Cornelis van Drimmelen has worked as a Business Manager at Capitec Bank since 2007 and previously worked at Coca-Cola Fortune and ABI Coca-Cola in various management roles. He received an MBA from Tshwane University of Technology in 2010 and served in the South African Defence Force from 1989-1990. He is seeking new opportunities in business management with over 20 years of experience in sales, marketing, operations, and people management.
This document discusses RESTafarian-ism and how REST principles can be applied at the National Library of Australia. It describes REST as being simple, language-neutral, and not using SOAP. It then addresses various technologies that could be used, such as wikis, and issues that may be faced, such as over-engineering and project coordination. Finally, it suggests some specific services like Lucene/Solr that could be useful and invites any questions.
El documento es una oración a la Virgen de la Macarena pidiéndole fuerzas y protección. La persona le pide a la Virgen que no la deje sola y que la llene de misericordia y fuerzas para enfrentar los retos de la vida, así como su bendición y compañía durante toda su vida y en el momento de su muerte.
This document provides a final report from the APEC Tourism Working Group on best practices for tourism accessibility for travelers with restricted physical ability. It conducted a survey of member economies to identify positive examples of accessibility in transportation, accommodations, tourism sites, travel planning, and customer services. The report aims to promote greater accessibility, raise awareness of the importance of inclusion, harmonize accessibility standards, and facilitate information exchange among members. It analyzes the examples collected according to categories and criteria to evaluate their potential transferability to other economies.
This newsletter introduces the Joint Programming Initiative on Agriculture, Food Security and Climate Change (FACCE-JPI). FACCE-JPI brings together European countries to identify, prioritize, and fund research to address challenges of meeting growing global food demand amid climate change. The newsletter provides an overview of FACCE-JPI activities including its scientific research agenda focused on sustainable food security, agricultural systems, trade-offs between food production and the environment, climate change adaptation, and greenhouse gas mitigation in agriculture and forestry. It also previews interviews with coordinators of the FACCE-JPI pilot project MACSUR on modeling agricultural systems.
Business Contacts Relations Management. Operativo de la A a la F. Azukre Cons...José Javier Agote
El documento describe las etapas clave para implementar una solución de gestión de relaciones con clientes (Business Contacts Relation Management). Primero, se debe identificar la estrategia, clientes, canales, productos y métricas. Luego, se ordenan conceptos, roles y procesos. Después, se define el modelo social de relación, se instancia en una solución tecnológica y se despliega de forma piloto. Finalmente, se establecen los siguientes pasos mediante una hoja de ruta continua de mejora.
Preliminary chapter of Certified Ethical Hacker courseDavid Sweigert
The document discusses the evolution of the term "hacker" and the Certified Ethical Hacker (CEH) credential. It provides context on how the term was originally used in admiration but is now often used negatively in the media. It also discusses the classic penetration testing approach tested by the CEH exam, which involves reconnaissance, scanning, gaining access, and privilege escalation without actual exploitation. The document notes some criticisms of this approach and discusses risks that testers need to be aware of to avoid violating laws.
El documento describe la anatomía del cerebelo. Se encuentra ubicado en la fosa craneal posterior e infratentorial del encéfalo. Está detrás del puente y no forma parte del tallo cerebral. Se divide en tres lóbulos y presenta varias fisuras. Tiene tres caras - superior, inferior y anterior - y se conecta al resto del encéfalo a través de tres pares de pedúnculos cerebelosos.
iCloud es un servicio de almacenamiento en la nube de Apple que permite a los usuarios acceder y sincronizar sus fotos, música, documentos, contactos, calendarios y más desde múltiples dispositivos a través de una cuenta de iCloud. El servicio reemplaza a MobileMe de Apple y sincroniza automáticamente el contenido entre dispositivos como iPhone, iPad, iPod touch y computadoras Mac.
El documento describe una excursión a la comarca de Babia, al norte de León, España. Los reyes de León solían escapar a Babia para descansar y cazar, dando origen a la expresión "estar en Babia". La excursión describe la visita al pueblo de Villafeliz de Arriba, incluyendo interacciones con perros y residentes locales. Luego, la ruta continúa por el valle de Panazal, con descripciones del paisaje incluyendo picos, ríos y nieves.
M&S Digital Labs: Lean product development, fast feedback & leopard print dre...hemalkuntawala
M&S Digital Labs developed an online styling app called Style Board to test assumptions about how customers would engage with creating and viewing outfits without brands or models. Data from the initial version showed 52% of visitors signed up and 39% created boards, with 36% higher conversion than other traffic. Further analysis of brand mixing, popular categories, and product relationships provided insights to improve engagement and sales conversion for the next versions.
El documento habla sobre la importancia de las semillas que se siembran a través de los pensamientos, palabras, actos y costumbres. Explica que estos darán forma al carácter y determinarán el destino y la vida. Recomienda sembrar semillas buenas con amor para cosechar frutos positivos. También enfatiza que la fuerza interior y la fe positiva influyen en los resultados de la vida.
The document lists various logo trends from 2007 such as Overlap, Pseudo Crest, Ribbons, Descending Dots, and Radiance. It also lists trends like Half, Eco Smart, Urban Vinyl, Rubber Bands, and Hubs. The document provides references to other resources on creative logos from 2007 and how leaves were a popular design element in logos that year.
Evaluación en Educación Física Escolar. La Observación de las Habilidades Motoras en la Clase de Educación Física - Presentación de la Conferencia disertada por el Prof. Alejandro Ruiz Díaz durante el 1º Congreso Provincial de Educación desarrollado los días 17, 18 y 19 de Noviembre de 2005 en la ciudad de Esquel, Chubut
Dorothy Cashier looks back on her remarkable life at age 82. She was born in the South and moved to Buchanan, Michigan as a young woman where she faced discrimination. This motivated her civil rights involvement with the NAACP. She raised nine children while working as a nurse and advocated for awareness of racial issues. Now slowing down, she remains a role model emphasizing education, family, and spirituality. She advises others to "get up and get to it" in making positive change.
II-SDV 2014 Design and development of a novel Patent Alerting Service (Bayer ...Dr. Haxel Consult
This document describes the design and development of a novel patent alerting system. The system uses advanced text mining to filter and categorize newly published patents into clearly defined project folders based on criteria like medical conditions, technologies, and compound classes. It adds key details and chemical structures to enriched patent records. Users can search, browse, and filter alerts and patent records. The system provides a powerful and precise way to track intellectual property in specific topics and represents an improvement over existing commercial alerting services.
http://www.universitieshandbook.com Die ABB Technikerschule ist eine dynamische, eidgenössisch anerkannte, höhere Fachschule. Sie besteht seit 1971 und hat sich zu einer hervorragenden Weiterbildungsmöglichkeit für technische Berufsleute entwickelt. Die Schule ist ausgeprägt leistungsbezogen und teamorientiert. Die Schule ist öffentlich und kann somit auch von Berufsleuten ausserhalb des ABB-Konzerns besucht werden.
Die erfolgreichen Absolventen erhalten ein eidgenössisch anerkanntes Diplom und sind berechtigt, den geschützten Titel "dipl. Techniker/in HF" zu führen. http://www.universitieshandbook.com
The document discusses pharmacovigilance and provides definitions and guidelines for reporting adverse drug reactions (ADRs). It describes how to fill out an ADR form, including a case example of a 59-year-old man who developed numbness and tingling due to metformin-induced vitamin B12 deficiency. It also reviews scales for assessing causality of ADRs, including the WHO causality scale and Naranjo algorithm. A second case example describes a patient who had a fixed drug eruption from levofloxacin with a history of prior reaction to the drug.
This document provides information on poisonings and substance abuse for paramedics. It defines poisoning and substance abuse. It describes how to identify the patient and poison, determine the nature of the poison, and assess inhaled, absorbed, ingested and injected poisons. It discusses the initial assessment, airway/breathing/circulation, and transport decision for a poisoned patient. It also covers alcohol, opioids, sedatives, inhalants, stimulants, marijuana, hallucinogens and anticholinergics.
This document contains the questions and answers from a Jeopardy-style medical knowledge competition. There are 5 categories with 5 questions in each category worth $100 to $500. The categories include case reports, specialty talks, clinic didactics, inpatient curriculum, and MKSAP specials. The questions cover a wide range of medical topics from lupus nephritis to C. difficile risk factors to syncope workup.
Drug use in elderly and techniques to avoid polypharmacyDrSahilKumar
The document discusses drug use in the elderly and techniques to avoid polypharmacy. It notes that the elderly population is growing and takes a significant portion of medications while also being more sensitive to drug effects due to physiological changes. Polypharmacy, defined as taking more than 5 medications, is common in the elderly due to multiple comorbidities and providers. This can increase risks of adverse drug reactions, interactions, and non-adherence. The document recommends techniques for optimal prescribing in the elderly like reviewing all medications, simplifying regimens, and eliminating unnecessary drugs to help prevent polypharmacy and its risks.
This document discusses RESTafarian-ism and how REST principles can be applied at the National Library of Australia. It describes REST as being simple, language-neutral, and not using SOAP. It then addresses various technologies that could be used, such as wikis, and issues that may be faced, such as over-engineering and project coordination. Finally, it suggests some specific services like Lucene/Solr that could be useful and invites any questions.
El documento es una oración a la Virgen de la Macarena pidiéndole fuerzas y protección. La persona le pide a la Virgen que no la deje sola y que la llene de misericordia y fuerzas para enfrentar los retos de la vida, así como su bendición y compañía durante toda su vida y en el momento de su muerte.
This document provides a final report from the APEC Tourism Working Group on best practices for tourism accessibility for travelers with restricted physical ability. It conducted a survey of member economies to identify positive examples of accessibility in transportation, accommodations, tourism sites, travel planning, and customer services. The report aims to promote greater accessibility, raise awareness of the importance of inclusion, harmonize accessibility standards, and facilitate information exchange among members. It analyzes the examples collected according to categories and criteria to evaluate their potential transferability to other economies.
This newsletter introduces the Joint Programming Initiative on Agriculture, Food Security and Climate Change (FACCE-JPI). FACCE-JPI brings together European countries to identify, prioritize, and fund research to address challenges of meeting growing global food demand amid climate change. The newsletter provides an overview of FACCE-JPI activities including its scientific research agenda focused on sustainable food security, agricultural systems, trade-offs between food production and the environment, climate change adaptation, and greenhouse gas mitigation in agriculture and forestry. It also previews interviews with coordinators of the FACCE-JPI pilot project MACSUR on modeling agricultural systems.
Business Contacts Relations Management. Operativo de la A a la F. Azukre Cons...José Javier Agote
El documento describe las etapas clave para implementar una solución de gestión de relaciones con clientes (Business Contacts Relation Management). Primero, se debe identificar la estrategia, clientes, canales, productos y métricas. Luego, se ordenan conceptos, roles y procesos. Después, se define el modelo social de relación, se instancia en una solución tecnológica y se despliega de forma piloto. Finalmente, se establecen los siguientes pasos mediante una hoja de ruta continua de mejora.
Preliminary chapter of Certified Ethical Hacker courseDavid Sweigert
The document discusses the evolution of the term "hacker" and the Certified Ethical Hacker (CEH) credential. It provides context on how the term was originally used in admiration but is now often used negatively in the media. It also discusses the classic penetration testing approach tested by the CEH exam, which involves reconnaissance, scanning, gaining access, and privilege escalation without actual exploitation. The document notes some criticisms of this approach and discusses risks that testers need to be aware of to avoid violating laws.
El documento describe la anatomía del cerebelo. Se encuentra ubicado en la fosa craneal posterior e infratentorial del encéfalo. Está detrás del puente y no forma parte del tallo cerebral. Se divide en tres lóbulos y presenta varias fisuras. Tiene tres caras - superior, inferior y anterior - y se conecta al resto del encéfalo a través de tres pares de pedúnculos cerebelosos.
iCloud es un servicio de almacenamiento en la nube de Apple que permite a los usuarios acceder y sincronizar sus fotos, música, documentos, contactos, calendarios y más desde múltiples dispositivos a través de una cuenta de iCloud. El servicio reemplaza a MobileMe de Apple y sincroniza automáticamente el contenido entre dispositivos como iPhone, iPad, iPod touch y computadoras Mac.
El documento describe una excursión a la comarca de Babia, al norte de León, España. Los reyes de León solían escapar a Babia para descansar y cazar, dando origen a la expresión "estar en Babia". La excursión describe la visita al pueblo de Villafeliz de Arriba, incluyendo interacciones con perros y residentes locales. Luego, la ruta continúa por el valle de Panazal, con descripciones del paisaje incluyendo picos, ríos y nieves.
M&S Digital Labs: Lean product development, fast feedback & leopard print dre...hemalkuntawala
M&S Digital Labs developed an online styling app called Style Board to test assumptions about how customers would engage with creating and viewing outfits without brands or models. Data from the initial version showed 52% of visitors signed up and 39% created boards, with 36% higher conversion than other traffic. Further analysis of brand mixing, popular categories, and product relationships provided insights to improve engagement and sales conversion for the next versions.
El documento habla sobre la importancia de las semillas que se siembran a través de los pensamientos, palabras, actos y costumbres. Explica que estos darán forma al carácter y determinarán el destino y la vida. Recomienda sembrar semillas buenas con amor para cosechar frutos positivos. También enfatiza que la fuerza interior y la fe positiva influyen en los resultados de la vida.
The document lists various logo trends from 2007 such as Overlap, Pseudo Crest, Ribbons, Descending Dots, and Radiance. It also lists trends like Half, Eco Smart, Urban Vinyl, Rubber Bands, and Hubs. The document provides references to other resources on creative logos from 2007 and how leaves were a popular design element in logos that year.
Evaluación en Educación Física Escolar. La Observación de las Habilidades Motoras en la Clase de Educación Física - Presentación de la Conferencia disertada por el Prof. Alejandro Ruiz Díaz durante el 1º Congreso Provincial de Educación desarrollado los días 17, 18 y 19 de Noviembre de 2005 en la ciudad de Esquel, Chubut
Dorothy Cashier looks back on her remarkable life at age 82. She was born in the South and moved to Buchanan, Michigan as a young woman where she faced discrimination. This motivated her civil rights involvement with the NAACP. She raised nine children while working as a nurse and advocated for awareness of racial issues. Now slowing down, she remains a role model emphasizing education, family, and spirituality. She advises others to "get up and get to it" in making positive change.
II-SDV 2014 Design and development of a novel Patent Alerting Service (Bayer ...Dr. Haxel Consult
This document describes the design and development of a novel patent alerting system. The system uses advanced text mining to filter and categorize newly published patents into clearly defined project folders based on criteria like medical conditions, technologies, and compound classes. It adds key details and chemical structures to enriched patent records. Users can search, browse, and filter alerts and patent records. The system provides a powerful and precise way to track intellectual property in specific topics and represents an improvement over existing commercial alerting services.
http://www.universitieshandbook.com Die ABB Technikerschule ist eine dynamische, eidgenössisch anerkannte, höhere Fachschule. Sie besteht seit 1971 und hat sich zu einer hervorragenden Weiterbildungsmöglichkeit für technische Berufsleute entwickelt. Die Schule ist ausgeprägt leistungsbezogen und teamorientiert. Die Schule ist öffentlich und kann somit auch von Berufsleuten ausserhalb des ABB-Konzerns besucht werden.
Die erfolgreichen Absolventen erhalten ein eidgenössisch anerkanntes Diplom und sind berechtigt, den geschützten Titel "dipl. Techniker/in HF" zu führen. http://www.universitieshandbook.com
The document discusses pharmacovigilance and provides definitions and guidelines for reporting adverse drug reactions (ADRs). It describes how to fill out an ADR form, including a case example of a 59-year-old man who developed numbness and tingling due to metformin-induced vitamin B12 deficiency. It also reviews scales for assessing causality of ADRs, including the WHO causality scale and Naranjo algorithm. A second case example describes a patient who had a fixed drug eruption from levofloxacin with a history of prior reaction to the drug.
This document provides information on poisonings and substance abuse for paramedics. It defines poisoning and substance abuse. It describes how to identify the patient and poison, determine the nature of the poison, and assess inhaled, absorbed, ingested and injected poisons. It discusses the initial assessment, airway/breathing/circulation, and transport decision for a poisoned patient. It also covers alcohol, opioids, sedatives, inhalants, stimulants, marijuana, hallucinogens and anticholinergics.
This document contains the questions and answers from a Jeopardy-style medical knowledge competition. There are 5 categories with 5 questions in each category worth $100 to $500. The categories include case reports, specialty talks, clinic didactics, inpatient curriculum, and MKSAP specials. The questions cover a wide range of medical topics from lupus nephritis to C. difficile risk factors to syncope workup.
Drug use in elderly and techniques to avoid polypharmacyDrSahilKumar
The document discusses drug use in the elderly and techniques to avoid polypharmacy. It notes that the elderly population is growing and takes a significant portion of medications while also being more sensitive to drug effects due to physiological changes. Polypharmacy, defined as taking more than 5 medications, is common in the elderly due to multiple comorbidities and providers. This can increase risks of adverse drug reactions, interactions, and non-adherence. The document recommends techniques for optimal prescribing in the elderly like reviewing all medications, simplifying regimens, and eliminating unnecessary drugs to help prevent polypharmacy and its risks.
Approach to drug poisoning in adults by Dr Alaa Elmassryalaa massry
This document provides information on drug overdoses and poisonings. It begins with an introduction by Dr. Alaa Eldeen Elmassry. It then poses questions about the epidemiology, toxidrome patterns, therapy, and specific poisonings clinicians may face. The rest of the document addresses these questions and topics, covering areas like cyanide poisoning treatment, opiate overdose signs, toxic ingestion differentials, effects of overdose vs. therapeutic doses, gastric decontamination, paracetamol overdose facts, poisoning statistics, toxic syndromes, vital signs and examinations in poisonings, and diagnostic tests.
Causality Assessment of Adverse Drug Reactions: An overviewDrSahilKumar
Causality assessment is important for determining if an adverse drug reaction is caused by a medication. Several scales exist to assess causality, including the WHO-UMC scale and Naranjo scale. The WHO-UMC scale categorizes causality as certain, probable, possible, unlikely, unclassified or unassessable based on factors like dechallenge/rechallenge outcomes, alternative causes, and temporal relationship. Accurately assessing causality prevents unnecessary drug withdrawals but also identifies true safety issues. Exercises are provided to help learn causality assessment.
Synthetic Drugs/Hormones - Boon or Bane- Concept of Dooshivisha and Gara VishaIJARIIT
21st century is the world full of synthetics and everyone are living in the influence of synthetic substances. Altered life
styles, food habits and irregular sleep pattern had resulted not only Non communicable disease but also resulting in reduced
immunity and is risking the person more for infections. Pharma Industry has grown as big as hierarchy in recent centauries
and introduces new chemical molecules quoting as capable for treating diabetes, hypertension etc. But bitter truth is prolonged
usage these medications itself has adverse effect on liver and kidneys causes hepatotoxicity and nephrotoxicity or organs
specific toxicity.
This white paper discusses evidence that hydroxychloroquine is safe and effective for treating COVID-19. It summarizes studies finding that HCQ has been safely used for over 65 years and billions of times without serious safety issues when used at recommended doses and durations. Experts in rheumatology, cardiology, and ophthalmology confirm HCQ is very low risk. The paper argues restrictions on HCQ use for COVID-19 are unwarranted and prevent doctors from effectively treating patients.
This document summarizes medications approved by the FDA for treating alcohol and opioid dependence. It discusses medications such as naltrexone and acamprosate for treating alcohol dependence, and methadone and buprenorphine for treating opioid dependence. The document also reviews genetic factors in addiction and withdrawal symptoms like kindling that can occur from repeated episodes of untreated alcohol withdrawal.
This document provides a guide to understanding common blood tests by listing each test and providing the normal range, potential causes of high or low values, and nutritional notes. It explains what each test measures, such as glucose measuring blood sugar levels and sodium and potassium measuring electrolyte balance, and health issues that could be indicated by abnormal results, to help readers understand their test results.
Alcohol Medication Assisted Recovery For Alcoholism 2008Stacy Seikel
This document summarizes medications approved by the FDA for the treatment of alcohol dependence. It discusses naltrexone, disulfiram, acamprosate, and Vivitrol as FDA-approved pharmacotherapies. Naltrexone is an opioid antagonist that blocks alcohol reward pathways. Disulfiram inhibits aldehyde dehydrogenase and causes unpleasant reactions if alcohol is consumed. Acamprosate is thought to stabilize glutamate and reduce protracted withdrawal symptoms. Vivitrol is an extended-release formulation of naltrexone given by monthly injection. Clinical trials show these medications can increase abstinence rates and reduce drinking days when used as an adjunct to psychosocial support.
This document provides an overview of drug rediscovery using the example of 6-thioguanine (6-TG) for inflammatory bowel disease (IBD). It discusses the current standard therapies for IBD, their limitations including side effects. 6-TG, which was previously only used for leukemia, shows promise as an alternative for patients who cannot tolerate standard thiopurines. Studies demonstrate the efficacy of 6-TG for IBD with response rates over 70% and less toxicity than other thiopurines. Low-dose 6-TG may avoid nodular regenerative hyperplasia seen at higher doses. Regulatory hurdles include the need for new clinical trials and difficulties with re-registration and distribution compared to redis
This document provides an overview of drug rediscovery using the example of 6-thioguanine (6-TG) for inflammatory bowel disease (IBD). It discusses the current standard therapies for IBD, their limitations including side effects. 6-TG, which was previously only used for leukemia, shows promise as an alternative for patients who cannot tolerate standard thiopurines. Studies demonstrate the efficacy of 6-TG for IBD with response rates over 70% and less toxicity than other thiopurines. Low-dose 6-TG may avoid nodular regenerative hyperplasia seen at higher doses. Regulatory hurdles include the need for new clinical trials and difficulties with re-registration and distribution compared to redis
This document discusses anticholinergic plant poisoning, including its introduction, toxidromes, common anticholinergic plants and their toxicities, pathophysiology, and emergency department management. It provides details on the anticholinergic toxidrome caused by plants like Datura, mandrake root, and deadly nightshade that contain tropane alkaloids like atropine and scopolamine. Management involves decontamination, supportive care for symptoms like agitation and seizures, and the antidote physostigmine for severe or unresponsive cases.
Medication Assisted Treatment for Alcoholism 2008Stacy Seikel
This document summarizes medications approved by the FDA for the treatment of alcohol dependence. It discusses three main medications: naltrexone, disulfiram, and acamprosate. Naltrexone is an opioid antagonist that blocks alcohol reward pathways. Disulfiram inhibits the enzyme aldehyde dehydrogenase and causes unpleasant reactions if alcohol is consumed. Acamprosate helps stabilize glutamate and may reduce protracted withdrawal symptoms. Clinical trials show these medications can reduce heavy drinking days and improve abstinence rates when used along with psychosocial support.
Hydroxyzine for anxiety how it works, dosage, and side effects!Health Club Finder
Globally, Hydroxyzine is used as a sedative to treat anxiety and depression. This article is to let you know all about the hydroxyzine for anxiety for health. To know more visit https://bit.ly/3c6Ro5q
1) Bromfenac is a nonsteroidal anti-inflammatory drug used for relieving pain and reducing inflammation.
2) It works by inhibiting the COX-1 and COX-2 enzymes to block prostaglandin synthesis.
3) Common adverse effects include abdominal pain, peptic ulcers, abnormal vision, lacrimation, asthma, cough, and myocardial infarction.
Similar to Could clonidine hydrochloride cause constipation e-healthme (20)
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
Here is the updated list of Top Best Ayurvedic medicine for Gas and Indigestion and those are Gas-O-Go Syp for Dyspepsia | Lavizyme Syrup for Acidity | Yumzyme Hepatoprotective Capsules etc
Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
Adhd Medication Shortage Uk - trinexpharmacy.comreignlana06
The UK is currently facing a Adhd Medication Shortage Uk, which has left many patients and their families grappling with uncertainty and frustration. ADHD, or Attention Deficit Hyperactivity Disorder, is a chronic condition that requires consistent medication to manage effectively. This shortage has highlighted the critical role these medications play in the daily lives of those affected by ADHD. Contact : +1 (747) 209 – 3649 E-mail : sales@trinexpharmacy.com
Could clonidine hydrochloride cause constipation e-healthme
1. 8/25/12 Could Clonidine hydrochloride cause Constipation? - eHealthMe
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Related symptom
- Constipation Aggravated
This is a post-marketing study of Constipation among people who take Clonidine
hydrochloride. The study is created by eHealthMe based on 32 reports from FDA and user
community. Common drugs
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What is Clonidine hydrochloride - Aspirin (134,557 reports)
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deficit hyperactivity disorder. Common side effects of Clonidine hydrochloride include high - Methotrexate (119,730 reports)
blood pressure, nausea, breathing difficulty, hypotension, nausea and vomiting. - Lipitor (117,129 reports)
More drugs ...
On Aug, 21, 2012:724 people reported to have side effects when taking
Clonidine hydrochloride. Among them, 32 people (4.42%) have
Constipation.
Time on Clonidine hydrochloride when people have Constipation * :
<1 1-6 6 - 12 1-2 2-5 5 - 10 10+
month months months years years years years
Constipation 20.00% 20.00% 20.00% 20.00% 13.33% 0.00% 6.67%
Gender of people who have Constipation when taking Clonidine
hydrochloride * :
Female Male
www.ehealthme.com/ds/clonidine+hydrochloride/constipation+aggravated 1/7
2. 8/25/12 Could Clonidine hydrochloride cause Constipation? - eHealthMe
Female Male
Constipation 75.68% 24.32%
Age of people who have Constipation when taking Clonidine hydrochloride
*:
0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Constipation 0.00% 0.00% 0.00% 0.00% 0.00% 34.29% 14.29% 51.43%
Severity of Constipation when taking Clonidine hydrochloride * :
most
least moderate severe
severe
Constipation 9.09% 45.45% 36.36% 9.09%
How people recovered from Constipation * :
n/a
Top conditions involved for these people * :
1. Blood pressure increased
2. Hypertension
3. Metastases to bone
4. Immunosuppression
5. Pain
Top co-used drugs for these people * :
1. Heparin sodium
2. Zometa
3. Nexium
4. Aspirin
5. Lantus
* Approximation only. Some reports may have incomplete information.
What is next?
post a comment or question
check whether constipation is from a drug or a condition
(for patients) bring a copy of the study to your health teams to ensure drug
risks and benefits are fully discussed and understood
get our mobile app: never miss a symptom, compare it with patients like
me in real time, and discuss it with doctors later
still have questions? Check related studies or user comments below
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3. 8/25/12 Could Clonidine hydrochloride cause Constipation? - eHealthMe
Comments from related studies:
From this study (3 years ago):
Never had a problem with regularity or weight gain till now. I basically live on
nuts, seeds and fruit and exercise regularly. (hypertension is hereditary). Have
experienced 8 pound weight gain and constant constipation. Increased my fiber
and now painful gas problems. Actually like the reduced hof flashes. Will it be
safe to try digestive enzymes while taking clonidine? Have tried them for three
days and it actually worked beautifully. I dropped two pounds and felt like myself
again. Would like to continue but wondered if anyone has heard about the safety
of using enzymes or herbal remedies while taking clonidine.
Reply
Could it be a symptom from a condition:
Constipation in Aggression (13 reports)
Constipation in Anxiety, Apprehension, Feeling Uptight, Jitters, Stress, Stress And
Anxiety, Tension (996 reports)
Constipation in Attention Deficit Hyperactivity Disorder (293 reports)
Constipation in Bipolar Disorder (384 reports)
Constipation in Blood Pressure Management (75 reports)
Constipation in Blood Pressure Systolic Abnormal
Constipation in Essential Hypertension (41 reports)
Constipation in Generalized Anxiety Disorder (82 reports)
Constipation in Gilles De La Tourette Syndrome (3 reports)
Constipation in Heart Attack (40 reports)
Constipation in High Blood Pressure (2,444 reports)
Constipation in Hot Flashes
Constipation in Hot Flush (21 reports)
Constipation in Insomnia (555 reports)
Constipation in Insomnia Related To Another Mental Condition
Constipation in Menopausal Symptoms (36 reports)
Constipation in Natural Short Sleeper
Constipation in Opiate Withdrawal (6 reports)
Constipation in Pain (2,830 reports)
Constipation in Post-traumatic Stress Disorder (41 reports)
Constipation in Secondary Hypertension
Constipation in Sleep Disorder (474 reports)
Constipation in Stress And Anxiety (992 reports)
Constipation in Stress In Childhood
Constipation in Tic
On eHealthMe, Clonidine Hydrochloride (clonidine hydrochloride) is often used for high
blood pressure. Find out below all the conditions the drug is used for, how effective it
is, and any alternative drugs that you can use to treat those same conditions.
What is the drug used for and how effective is it:
Clonidine hydrochloride is used in:
Aggression
Anxiety, apprehension, feeling uptight, jitters, stress, stress and anxiety,
www.ehealthme.com/ds/clonidine+hydrochloride/constipation+aggravated 3/7
4. 8/25/12 Could Clonidine hydrochloride cause Constipation? - eHealthMe
Anxiety, apprehension, feeling uptight, jitters, stress, stress and anxiety,
tension
Attention deficit hyperactivity disorder
Bipolar disorder
Blood pressure management
Blood pressure systolic abnormal
Essential hypertension
Generalized anxiety disorder
Gilles de la tourette syndrome
Heart attack
High blood pressure
Hot flashes
Hot flush
Insomnia
Insomnia related to another mental condition
Menopausal symptoms
Natural short sleeper
Opiate withdrawal
Pain
Post-traumatic stress disorder
Secondary hypertension
Sleep disorder
Stress and anxiety
Stress in childhood
Tic
Other drugs that are used to treat the same conditions:
Clonidine hydrochloride alternatives:
Aggression (5 drugs)
Anxiety, apprehension, feeling uptight, jitters, stress, stress and anxiety,
tension (128 drugs)
Attention deficit hyperactivity disorder (58 drugs)
Bipolar disorder (67 drugs)
Blood pressure management (75 drugs)
Blood pressure systolic abnormal (3 drugs)
Essential hypertension (33 drugs)
Generalized anxiety disorder (67 drugs)
Gilles de la tourette syndrome (4 drugs)
Heart attack (27 drugs)
High blood pressure (181 drugs)
Hot flashes (8 drugs)
Hot flush (11 drugs)
Insomnia (84 drugs)
Insomnia related to another mental condition (26 drugs)
Menopausal symptoms (18 drugs)
Natural short sleeper (32 drugs)
Opiate withdrawal (6 drugs)
Pain (184 drugs)
Post-traumatic stress disorder (30 drugs)
Secondary hypertension (1 drug)
Sleep disorder (64 drugs)
Stress and anxiety (128 drugs)
Stress in childhood (2 drugs)
Tic (1 drug)
Browse 1,259 Clonidine hydrochloride side effects from A to Z:
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Browse Clonidine hydrochloride drug interactions with drugs from A to
Z:
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Drugs in real world that are associated with:
Constipation
Constipation is also known as: irregularity of bowels, lack of regular bowel movements,
stool softener, stool softener needs.
www.ehealthme.com/ds/clonidine+hydrochloride/constipation+aggravated 4/7
5. 8/25/12 Could Clonidine hydrochloride cause Constipation? - eHealthMe
Recent Clonidine hydrochloride drug interactions:
Clonidine Hydrochloride and Gnaphalium uliginosum drug interactions
Clonidine Hydrochloride and Hempseed drug interactions (2 reports)
Clonidine Hydrochloride and Horsebane drug interactions
Clonidine Hydrochloride and Hydrochlorothiazide drug interactions (1,032 reports)
Clonidine Hydrochloride and Indian Chocolate drug interactions
Clonidine Hydrochloride and Juglans regia drug interactions
Clonidine Hydrochloride and Juniperus communis drug interactions
Clonidine Hydrochloride and Leberkraut drug interactions
Clonidine Hydrochloride and Louisa drug interactions
Clonidine Hydrochloride and Mountain Pink drug interactions
Clonidine Hydrochloride and Mouth-Smart drug interactions
Clonidine Hydrochloride and Pepper Wood drug interactions
Clonidine Hydrochloride and Red Root drug interactions
Clonidine Hydrochloride and Red Valerian drug interactions
Clonidine Hydrochloride and Sea Ash drug interactions
Clonidine Hydrochloride and Sponge Cucumber drug interactions
Clonidine Hydrochloride and Srungavera drug interactions
Clonidine Hydrochloride and String Of Sovereigns drug interactions
Clonidine Hydrochloride and Strophanthi Grati Semen drug interactions
Clonidine Hydrochloride and Vyvanse drug interactions (71 reports)
Recent Constipation related Clonidine hydrochloride drug interactions:
Constipation in Clonidine Hydrochloride and Hydrochlorothiazide (8 reports)
Constipation in Clonidine Hydrochloride and Vyvanse (2 reports)
Recent related drug checks on
eHealthMe:
Vitamin D (Banner Pharmacaps) - 50,000
IU, Coreg (Smithkline Beecham) - 6.25MG,
Digoxin (Stevens J) - 0.125MG, Zocor
(Merck) - 40MG, Flomax (Boehringer
Ingelheim) - 0.4MG, Diovan (Novartis) -
80MG, Bisacodyl, Proventil-hfa (3m) - EQ
0.09MG BASE/INH, Nitro-dur (Key Pharms)
- 0.2MG/HR, Restoril (Tyco Hlthcare) -
15MG, Coumadin (Bristol Myers Squibb) -
4MG, Colace, Nitrostat (Parke Davis) - 0.8MG/ML, Prilosec (Astrazeneca) - 40MG,
Zofran (Glaxosmithkline) - EQ 4MG BASE, Tylenol (caplet) (Mcneil Cons) - 650MG,
Clonidine Hydrochloride (Watson Labs) - 0.1MG drug interactions for Aphasia,
Congestive Heart Failure, Atrial Fibrillation, Cholesterol, Overactive Bladder,
Constipation, Pneumonia, Insomnia, Stool Softener, Chest Pain, Gerd, Pain, Blood
Pressure Fluctuation: Constipation
Clonidine Hydrochloride, Diovan, Atenolol, Plavix, Aspirin, Glyburide, Lipitor drug
interactions for Renal Cyst, Blood Pressure Increased, Cardiac Disorder, Diabetes
Mellitus: Constipation
Heparin Sodium, Novel Erythropoiesis Stimulating Protein, Iron, Midodrine
Hydrochloride, Antibiotics, Dianeal, Clonidine Hydrochloride, Lorazepam, Phoslo,
Renagel, Prochlorperazine, Corticosteroid Nos, Sensipar, Multi-vitamins drug
interactions for Haemodialysis, Peritoneal Dialysis, Renal Failure: Constipation
Vistaril (Pfizer) - 25MG/ML, Cardura Xl (Pfizer) - EQ 4MG BASE, Prozac, Clonidine
Hydrochloride (Watson Labs) - 0.2MG, Depakote (Abbott) - EQ 500MG VALPROIC
www.ehealthme.com/ds/clonidine+hydrochloride/constipation+aggravated 5/7
6. 8/25/12 Could Clonidine hydrochloride cause Constipation? - eHealthMe
Hydrochloride (Watson Labs) - 0.2MG, Depakote (Abbott) - EQ 500MG VALPROIC
ACID, Fish Oil, Vitamin C drug interactions for Stress And Anxiety, Urinary Retention,
Depression, High Blood Pressure, Mania, Vitamin Supplementation, Vitamin C:
Constipation
Clonazepam - 0.5MG, Clonidine Hydrochloride (Mylan) - 0.1MG, Hydrochlorothiazide
(Mylan) - 50MG, Prevacid (Tap Pharm) - 30MG drug interactions for Turner
Syndrome, High Blood Pressure, Acid Reflux: Constipation
Clonidine Hydrochloride (Mylan) - 0.2MG side effects for Hypertension: Constipation
Carvedilol (Teva) - 6.25MG, Pravastatin Sodium (Teva) - 40MG, Nifedipine, Clonidine
Hydrochloride (Mylan) - 0.1MG, Metformin Hydrochloride (Andrx Pharms) - 500MG,
Levothroid - 0.075MG, Glimepiride (Teva) - 4MG, Mirtazapine (Roxane) - 15MG,
Abilify (Otsuka) - 10MG drug interactions for High Blood Pressure, Diabetes, Thyroid
Disorder, Depression: Constipation
Norvasc, Effexor Xr (Wyeth Pharms Inc) - EQ 150MG BASE, Flomax (Boehringer
Ingelheim) - 0.4MG, Prilosec (Astrazeneca) - 20MG, Clonidine Hydrochloride (Mylan)
- 0.2MG, Crestor (Ipr) - 10MG drug interactions for Heart Block Congenital, Chronic
Depression, Urinary Frequency, Reflux Gastritis, Blood Pressure Inadequately
Controlled, Blood Cholesterol Increased: Constipation
Norvasc, Effexor Xr (Wyeth Pharms Inc) - EQ 150MG BASE, Flomax (Boehringer
Ingelheim) - 0.4MG, Prilosec (Astrazeneca) - 20MG, Clonidine Hydrochloride (Mylan)
- 0.2MG, Crestor (Ipr) - 10MG drug interactions for Heart Block Congenital, Chronic
Depression, Urinary Frequency, Reflux Gastritis, Blood Pressure Inadequately
Controlled, Blood Cholesterol Increased: Constipation
Clonidine Hydrochloride (Actavis Elizabeth) - 0.1MG, Duragesic-75 (Ortho Mcneil
Janssen) - 75UGM/HR, Duragesic-12 (Ortho Mcneil Janssen) - 12.5UGM/HR,
Lamotrigine (Aurobindo Pharma) - 100MG, Codeine, Aspirin, Apap Formula No. 2
(Scherer Labs) - 150MG;180MG;15MG, Alphagan, Cosopt (Merck) - EQ 2%
BASE;EQ 0.5% BASE drug interactions for Withdrawal From Opioids, Pain - Back,
Bipolar Disorder, Sleep Disorder, Glaucoma: Constipation
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NOTE: The study is based on active ingredients and brand name. Other drugs that have
the same active ingredients are not considered.
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician
since doing so could be hazardous to your health.
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