Coming Home with The Wilkinsons is a rare reunion of this internationally acclaimed band from Trenton ON, an event that also features a night of high energy entertainment with an ensemble cast of other well known music and comedy acts. This event is set for May 3rd, 2014 at The Empire Theatre in Belleville ON, and is put on in support of The James Fund--an organization that raises awareness and research funding for neuroblastoma. This aggressive disease is one of the top three childhood cancers.
Coming Home with The Wilkinsons is a rare reunion of this internationally acclaimed band from Trenton ON, an event that also features a night of high energy entertainment with an ensemble cast of other well known music and comedy acts. This event is set for May 3rd, 2014 at The Empire Theatre in Belleville ON, and is put on in support of The James Fund--an organization that raises awareness and research funding for neuroblastoma. This aggressive disease is one of the top three childhood cancers.
Anti ulcer drugs and their Advance pharmacology ||
Anti-ulcer drugs are medications used to prevent and treat ulcers in the stomach and upper part of the small intestine (duodenal ulcers). These ulcers are often caused by an imbalance between stomach acid and the mucosal lining, which protects the stomach lining.
||Scope: Overview of various classes of anti-ulcer drugs, their mechanisms of action, indications, side effects, and clinical considerations.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
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New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
micro teaching on communication m.sc nursing.pdfAnurag Sharma
Microteaching is a unique model of practice teaching. It is a viable instrument for the. desired change in the teaching behavior or the behavior potential which, in specified types of real. classroom situations, tends to facilitate the achievement of specified types of objectives.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
1. Coming Home
with
The Wilkinsons
AN EVENING OF ENTERTAINMENT
IN SUPPORT OF
THE JAMES FUND
TO BE HELD MAY 3RD, 2014
AT
THE EMPIRE THEATRE, BELLEVILLE, ONTARIO
2. Executive Summary
— An evening of high energy entertainment to be held at Belleville,
Ontario’s Empire Theatre on Saturday, May 3rd 2014.
¡
¡
Headlining this event is a one-time reunion of the internationally acclaimed
band, The Wilkinsons, who originate from the area.
Special guests include Small Town Pistols, Sleddogs, The Abrams Brothers, Sam and
Emma McNichols, and comedians…Nick Foley & Friends.
— Profits from this event will be presented to The James Fund
¡
The James Fund raises funds and awareness towards a cure for the aggressive
childhood cancer, neuroblastoma.
— Several levels of Executive and Private Sponsorship packages are
currently available in support of this event.
These charts provide background on
The James Fund and
sponsorship packages for The Event.
3. Neuroblastoma
— Cancer is the #1 cause of death by disease in children.
— Neuroblastoma is one of the three major childhood cancers.
— Progress lagging the other 2 due to lack of research funding.
— One child dies every 14 hours in North America from
neuroblastoma; it is also the most common cancer in infancy.
— Nearly half of neuroblastoma cases occur in children less than
two years of age.
— Survival rates for high risk neuroblastoma is approximately
15%. The majority of survivors from all classes of
neuroblastoma have long-term effects from treatments.
— Comprises 6 to 10% of all childhood cancers and 15% of cancer
deaths in children.
4. The James Fund
— Mission: Our mission is “to inspire change by sharing the unfolding story of our
search to find a cure for neuroblastoma by raising funds while supporting
families.”
— Started by one family desperate to save their child but since turned into a movement
and funding model emulated and celebrated around the world.
— The James Fund has grown into the largest neuroblastoma funding group by far in
Canada, and one of the largest dedicated to neuroblastoma in the world.
— Brought in over $12,000,000, having taken the top prize for research in the field,
and having established a blueprint that is now copied by countless family funds all
over the planet.
— http://www.jamesfund.com
5. Harvest Moon Presents
— Objective
¡ First of planned annual benefit concerts
¡ Goal is to raise $50,000 for The James Fund
— Details
¡ May 3rd, 2014, Empire Theatre Belleville, Ontario
¡ Theme: Country, Country Rock, Retro, and Comedy
¡ Significant event: The Wilkinsons reunion (Juno winners,
Billboard hits, international acclaim for this local band)
¡ Special Guests: Small Town Pistols, The Abrams Brothers,
Sleddogs, Sam and Emma McNichols and comedians Nick
Foley and Friends
6. Background on the Acts
— The Wilkinsons: Founded in 1997 the band has received 13 Canadian Country
Music Awards, one Juno Award and two Grammy nominations with hit singles “26
Cents” (#1 on Canadian country music charts, #1 on the R&R charts, and #3 on
Billboard’s Hot Country Singles) and “Fly (the Angel Song)” which hit #1 in Canada.
— Small Town Pistols: Self-titled debut album released in February 2013
with its second single “Living on the Outside” debuting on the Canadian Hot 100. Other
hits include “Blame It On the Radio” and “Anthem of a Runaway.”
— The Abrams Brothers: Named Emerging Artist of the Year in 2005 at the
Canadian Bluegrass Music awards, The Abrams Brothers have produced five albums
including “Northern Redemption.”
— Sleddog: Numerous hits in the Canadian Top 100,
including “Bye Bye Life,”
“Perfect Place,” “Take Me Away,” “Tragic,” “Lack of Control” and “Sweet Lorraine.”
— Emma and Sam McNichols: An up and coming, young local group
from Kingston, Ontario, they are currently recording songs at the Tragically Hip studio.
7. Coming Home with The Wilkinsons
— Venue: The Empire Theatre
¡ Built in 1938 - extraordinary atmosphere, intimate with
pristine sound, well recognized by the music industry
¡ 708 seats, upper and lower hospitality areas
¡ www.theempiretheatre.com
¡ www.facebook.com/pages/The-Empire-Theatre/12282523209
— Ticket Structure
¡ Four Levels of VIP Sponsorships: Platinum, Gold, Silver and Bronze
¡ Orchestra pricing
¡ Balcony pricing
Please join us for this important evening of awareness and fun!
We would be PROUD to have your organization
sponsor our Coming Home with The Wilkinsons event!
8. Definition of Sponsorship Levels
Platinum -- $10,000
ONLY ONE PLATINUM Sponsor
Includes:
— Corporate Exposure
¡
¡
¡
¡
¡
Association with event: “Coming Home with The Wilkinsons, presented by: _______”
Radio mention with Event Publicity
Mention in all social media and printed literature
Corporate displays at The Event
Photo-op with Headliners & Your Company Logo
— 12 VIP Tickets – first choice of reserved block of premium seating
— Access to The Empire before the doors open
¡
Lower hospitality section
— VIP ticket invitation to exclusive After-Party
¡
¡
Meet & Greet the Acts in upper hospitality section
Auction
9. Definition of Sponsorship Levels
Gold -- $5,000
Includes:
— Corporate Exposure
¡
¡
¡
¡
Radio mention with Event Publicity
Mention in all social media and printed literature
Corporate displays at The Event
Photo-op with Headliners & Your Company Logo
— 4 VIP Tickets – second choice of reserved block of premium seating
— 4 Regular Orchestra Tickets – also selected with VIP tickets
— Access to The Empire before the doors open
¡
Lower hospitality section
— VIP ticket invitation to exclusive After-Party
¡
¡
Meet & Greet the Acts in upper hospitality section
Auction
10. Definition of Sponsorship Levels
Silver -- $1,000
Includes:
— Exposure
¡
¡
¡
Inclusion in Sponsorship List
Mention in social media
Corporate displays at The Event
— 2 VIP Tickets – third choice of reserved block of premium seating
— 2 Regular Orchestra Tickets– also selected with VIP tickets
— VIP ticket invitation to to exclusive After-Party
¡
¡
Meet & Greet the Acts in upper hospitality section
Auction
11. Definition of Sponsorship Levels
Bronze -- $500
Includes:
— Exposure
¡
¡
Inclusion in Sponsorship List
Mention in social media
— 2 VIP Tickets – fourth choice of reserved block of premium seating
— VIP ticket invitation to to exclusive After-Party
¡
¡
Meet & Greet the Acts in upper hospitality section
Auction
13. Contact Information
— Please contact any of the following individuals for
additional information or purchases and coordination
¡
¡
¡
¡
Glenn Lidstone
Barb Cheesebrough
Kelly Slawter
Kelly Sakamoto
613-962-5177 glenn.lidstone@gmail.com
905-355-4022
613-243-4122
613-967-0895
— Please note: Silent auction items will also be gratefully accepted for the
After Party event.
14. Amanda & Tyler
Grandma Ida would be proud.
Amanda Wilkinson was building on an already glittering music career when she released her slick and impressive solo debut in 2007. But the
diminutive singer-songwriter wasn’t satisfied, even if everybody else was. Having given seven of the 10 songs on her record to other composers, Amanda
was hungry for full-blown independence.
“I felt like it was my responsibility that the next project I would do, I’d be saying something as a grown person,” she says, explaining why she exiled
herself to Nashville in 2010 to bunker down and get back to her first love—songwriting.
Meanwhile, some 1300 kilometres away, Tyler Wilkinson was also busy forging his own identity when the fateful call came from his sister. “I had a
rock band in Ontario for six years that I was working with pretty much full time,” he says, “and Amanda was, like, ‘Come on down and write with me!’ I
was thinking I’d be going to help write for her future solo project.”
For all intents and purposes he probably was. Instead, 15 or 20 songs into their collaboration, something started to feel familiar and right. “I think
there was kind of an, ‘Ah ha!’ moment where we were both, like, ‘Holy shit!’” he chuckles. Enter Small Town Pistols, named after the small but powerful
family matriarch whose spirit Amanda seemed to inherit. “People would say, ‘You’re like Grandma Ida,’ she says. “‘She was a pistol!’”
While nobody is likely to forget that Amanda and Tyler enjoyed phenomenal success together years earlier with the Wilkinsons, one listen to Small
Town Pistols reveals an entirely different beast. Their debut self-titled album profits from a long connection as performers— something immediately
heard when they wrap their close harmonies around a winding vocal melody in “Easy as Breathing”—but there’s also a newfound sophistication and
scope at work here.
From the chiming, modern pop of “Blame the Radio”, to the galloping Fleetwood Mac redux of “Love is Gonna Find You”, the songwriting and
performances their first record are, as Tyler bluntly states, “just more mature.” Adds Amanda, “It’s a jump from being a 16 year-old, when we released
our first record as the Wilkinsons, to being a near 30 year-old with different things to say entirely. We’re saying things we’d say as adults.”
The timing obviously works. Amanda sounds amazed when she recalls the “fluency” of their writing sabbatical together. “It just kept spilling out,”
she says, while the duo’s interior journey—both were recovering from broken relationships at the time—was doubled in some ways as they pieced the
album together on an impulsive path that took them from Nashville, to Toronto, to Vancouver.
In the course of things, the Pistols also invited a varied bunch of friends to lend a hand. The effusive modern country of “Colour Blind” comes
courtesy of Chad Kroeger’s creative partner Joey Moi, while the slightly eccentric path taken in “Walk Tall” is the result of a hook up with Steve Bays of
Hot Hot Heat. Amanda says they approached this project “with no rules,” and the payload is an album that swings naturally from the affectionate
vintage country pastiche of “It’s You” to the grandeur of “Friends” or “Living on the Outside”.
With a majestic feel that recalls classic Jimmy Webb, “Living on the Outside” is a track where the duo’s attention to songcraft couldn’t be any
clearer, or more affecting. It’s significant therefore that it’s also one of three songs co-written by their father, Steve. While Amanda and Tyler cite
everything from Lefty Frizzell to Emmylou Harris, the Beatles, and Death Cab’s Ben Gibbard as inspiration, she’s happy to admit that “the biggest
influence of all is always our dad.” The only difference now is their autonomy. Meanwhile, somewhere, Grandma Ida is tapping a small foot in approval.