Bisphenol A (BPA) is used to manufacture polycarbonate plastics and epoxy resins. It can leach from dental resins and materials used in orthodontic treatments. While not toxic at current exposure levels, BPA is estrogenic and has been linked to various health issues like cancer. Reducing exposure by cleaning surfaces after placement can help lower BPA absorption from dental materials.

1. Bisphenol A
-Define
-Structure
-Side effect
-Treatment
By :
khalid jasser falah
Supervision:
Dr. sulafa khair al- deen
Stage :
Third stage – college of dentistry
Tikrit university

2. Bisphenol A
What is the Bisphenol A
Bisphenol A (BPA), a colourless crystalline solid belonging to the family of organic
compounds; its molecular formula is C15H16O2. BPA is best known for its use in the
manufacture of polycarbonateplastics and epoxy resins,
In the early 21st century, global BPA production amounted to more than 6 billion
pounds (2.7 billion kilograms) annually, roughly one-third of which was made in
the United States. Human exposure in that country particularly was deemed to be
widespread; a study published in 2008 estimated that more than 90 percent of
Americans aged six and older had detectable levels of BPA in their urine.(1)
Bisphenol A(2)
Use of BisphenolA in dentistry
BPA has been reported to leach from someresin based dental restorative
materials and materials used for orthodontic treatment. To confirm and
update previous findings, especially in light of the new temporary lower
threshold value for tolerable daily BPA intake, we have investigated the
leaching of BPA from 4 composite filling materials, 3 sealants and 2
orthodontic bonding materials. (3)
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Toxicity of Bisphenol A

3. Bisphenols are chemical components found in dental composites and sealants.
Similar compounds also can be found in baby bottles, food can liners, and even
drinking water. Bisphenols have gained attention recently because they, like other
natural and synthetic compounds, including hormone-based drugs and soybean
products, have the capacity to mimic the actions of the hormone estrogen in living
cells and animals. Such estrogenic activity has been linked to a variety of health
problems, including breast and prostate cancer, metabolic disorders, and
reproductive dysfunction. In early 2010, the FDA issued a report stating that there are
some concerns about the safety of bisphenols in food products and called for more
research on bisphenols toxicity. At present, no regulatory or professional organization
has expressed concern about health effects of bisphenols in dental materials. (4)
BPA is released from dental resins through salivary enzymatic hydrolysis of BPA
derivatives, and BPA is detectable in saliva for up to 3 hours after resin placement.
The quantity and duration of systemic BPAabsorption is not clear from the available
data. (5)
To reduce it toxicity
BPA exposure can be reduced by cleaning and rinsing surfaces of sealants and
composites immediately after placement.(5)
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4. (1) Bisphenol A
CHEMICAL COMPOUND
WRITTEN BY:
 Kara Rogers
LAST UPDATED: Mar 12, 2020 See Article History
(2) wikipedia
(3) Presence and leaching of bisphenol a (BPA) from dental
materials
Rune Becher, Hanne Wellendorf, [...], and Hilde Molvig Kopperud
(4) Current status of potential bisphenol toxicity in
dentistry.
Daniel E Myers, Reinhold J Hutz
General dentistry 59 (4), 262-265, 2011
(5) Bisphenol A and related compounds in dental
materials
Abby F Fleisch, Perry E Sheffield, Courtney Chinn, Burton
L Edelstein, Philip J Landrigan
Pediatrics 126 (4), 760-768, 2010
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