This document summarizes an editorial that discusses a study finding glycophorin-rich cores in pulmonary artery plaques from patients with chronic thromboembolic pulmonary hypertension. Glycophorins are proteins in erythrocyte membranes. The study suggests that thromboembolic material (erythrocyte membranes) may play a role in atheromatous core formation. While this is a novel hypothesis, extrapolating the findings to coronary atherosclerosis is challenging given differences in disease etiology and the lack of evidence examining glycophorin staining in coronary arteries. In conclusion, the editorial discusses that red blood cell membranes contain lipid-rich components that could contribute to atheroma formation, but more evidence is needed to substantiate this
This document celebrates women of all ages and nationalities who persevere in creating a better world. It discusses how women manage difficulties with cheerfulness and joy, battle injustice with rebellion, and deny themselves to support their families. Women are described as loving unconditionally, finding happiness in others' good news and suffering from the loss of friends. They are portrayed as strong even when lacking energy and able to heal with hugs and kisses. The only defect of women mentioned is that they sometimes forget their own worth.
The document discusses several different vehicles:
- The Ford Model T, the first affordable automobile produced from 1908-1927 and helped popularize car ownership.
- The Corvette sports car known for its performance upgrades like wider tires and suspension tuning.
- The Toyota Prius hybrid, which has a four cylinder engine and electric motor producing 134 hp together. It has different driving modes and contemporary interior.
Alicia worked on a cross functional team to improve document processes and templates for the D-series. She contributed her expertise while keeping the customer experience as the top priority. The team directly addressed issues to enhance the customer experience.
El documento discute qué bienes y servicios deben producirse y en qué cantidades para satisfacer las necesidades de la población. Explica que los bienes y servicios son producidos por empresas privadas y el estado para el consumo y la producción. También describe los factores de producción como la tierra, el trabajo, el capital y la tecnología que las empresas utilizan. Finalmente, concluye que se necesita mayor producción y empleo para abastecer a toda la población.
170 insulin signaling & vldl overproductionSHAPE Society
1) The document discusses insulin signaling and VLDL overproduction in insulin resistance. It examines how fructose feeding impairs tyrosine phosphorylation of the insulin receptor, IRS-1, and IRS-2 in hepatocytes, reducing PI3-kinase activity and Akt phosphorylation while enhancing PTP-1B mass and activity.
2) It also finds that inhibition of cellular phosphatase activity with vanadate enhances insulin signaling and reduces ApoB secretion from hepatocytes by increasing insulin receptor phosphorylation, stabilizing cellular ApoB levels, and decreasing ApoB secretion.
3) The findings provide evidence that impaired insulin signaling and reduced PI3-kinase activity contribute to overproduction of VLDL in
This document discusses the use of coronary CT angiography (CTA) to detect and characterize coronary atherosclerosis beyond just detecting coronary stenoses. CTA can identify calcified plaques, non-calcified plaques, and mixed plaques. It can detect atheromas and characterize plaque density. CTA can also identify intracoronary thrombi and myocardial infarction scars. The document outlines the CTA scanning parameters and techniques used to minimize motion artifacts and optimize image quality for plaque detection and characterization.
This document summarizes an editorial that discusses a study finding glycophorin-rich cores in pulmonary artery plaques from patients with chronic thromboembolic pulmonary hypertension. Glycophorins are proteins in erythrocyte membranes. The study suggests that thromboembolic material (erythrocyte membranes) may play a role in atheromatous core formation. While this is a novel hypothesis, extrapolating the findings to coronary atherosclerosis is challenging given differences in disease etiology and the lack of evidence examining glycophorin staining in coronary arteries. In conclusion, the editorial discusses that red blood cell membranes contain lipid-rich components that could contribute to atheroma formation, but more evidence is needed to substantiate this
This document celebrates women of all ages and nationalities who persevere in creating a better world. It discusses how women manage difficulties with cheerfulness and joy, battle injustice with rebellion, and deny themselves to support their families. Women are described as loving unconditionally, finding happiness in others' good news and suffering from the loss of friends. They are portrayed as strong even when lacking energy and able to heal with hugs and kisses. The only defect of women mentioned is that they sometimes forget their own worth.
The document discusses several different vehicles:
- The Ford Model T, the first affordable automobile produced from 1908-1927 and helped popularize car ownership.
- The Corvette sports car known for its performance upgrades like wider tires and suspension tuning.
- The Toyota Prius hybrid, which has a four cylinder engine and electric motor producing 134 hp together. It has different driving modes and contemporary interior.
Alicia worked on a cross functional team to improve document processes and templates for the D-series. She contributed her expertise while keeping the customer experience as the top priority. The team directly addressed issues to enhance the customer experience.
El documento discute qué bienes y servicios deben producirse y en qué cantidades para satisfacer las necesidades de la población. Explica que los bienes y servicios son producidos por empresas privadas y el estado para el consumo y la producción. También describe los factores de producción como la tierra, el trabajo, el capital y la tecnología que las empresas utilizan. Finalmente, concluye que se necesita mayor producción y empleo para abastecer a toda la población.
170 insulin signaling & vldl overproductionSHAPE Society
1) The document discusses insulin signaling and VLDL overproduction in insulin resistance. It examines how fructose feeding impairs tyrosine phosphorylation of the insulin receptor, IRS-1, and IRS-2 in hepatocytes, reducing PI3-kinase activity and Akt phosphorylation while enhancing PTP-1B mass and activity.
2) It also finds that inhibition of cellular phosphatase activity with vanadate enhances insulin signaling and reduces ApoB secretion from hepatocytes by increasing insulin receptor phosphorylation, stabilizing cellular ApoB levels, and decreasing ApoB secretion.
3) The findings provide evidence that impaired insulin signaling and reduced PI3-kinase activity contribute to overproduction of VLDL in
This document discusses the use of coronary CT angiography (CTA) to detect and characterize coronary atherosclerosis beyond just detecting coronary stenoses. CTA can identify calcified plaques, non-calcified plaques, and mixed plaques. It can detect atheromas and characterize plaque density. CTA can also identify intracoronary thrombi and myocardial infarction scars. The document outlines the CTA scanning parameters and techniques used to minimize motion artifacts and optimize image quality for plaque detection and characterization.