The study by Meybohm et al. (2013) involving 198 patients with platelet counts below 80,000/mcl found that none of the assays or point-of-care tests reliably predict bleeding risk. It suggests that clinical prediction rules serve as guides rather than definitive predictors. Additionally, big data analysis may offer insights into predicting bleeding risks and other complications.

1. Can we predict who will
bleed?

14. Meybohm et al. Critical Care 2013, 17:218

21. N = 198, patients with platelet count <
80,000/mcl

31. To Conclude…
• None of the assays or POCCs predict risk of bleeding with acceptable
reliability.
• Clinical prediction rules are guides only, not predictors..
• Big data analysis might predict risk of bleeding amongst a host of
other potential complications