Dr. San probiotic lozenges contain the probiotic strain Lactobacillus rhamnosus SD11, which can optimize the oral microbiome and significantly reduce tooth decay. The lozenges are an innovative oral health product meant to improve dental health in a non-invasive way. Clinical trials showed L. rhamnosus SD11 reduces levels of cavity-causing bacteria in subjects' mouths after consumption. The company believes these probiotic lozenges can significantly impact oral health and the dental industry.

6. DR. SAN
: Probiotic lozenges for better oral health
Mr. Sarn Dootsaengthong
Cheif Executive Officer (CEO), Dental Sweet Co., Ltd., Thailand
dentalsweets@gmail.com
Dental caries (ECC) is still considered as a serious public-health problem in worldwide, due to its impact
on individuals and communities in terms of pain and suffering, impairment of function and reduced quality of
life. This crucial cause of dental caries affects not only individual health but also the socio-economy as a whole.
The global monetary spending for oral treatment grows at a very significant rate every year. Recently, probiotics
have been suggested for preventing of oral diseases including dental caries.
Dr. SAN is an innovative oral health product that is created based on the objective of improving oral
health in a non-invasive way. The key ingredient of this product contain a novel probiotic strain Lactobacillus
rhamnosus SD11 that has the ability to optimize the balance in oral cavity that can significantly reduce the chance
of having teeth caries. The product comes in the form of lozenges with mint flavor which people are already
familiar with.
Lactobacillus rhamnosus SD11 exhibits several properties to be a good probiotic for promoting oral
health. It could inhibit the growth of cariogenic bacteria by producing a bacteriocin against oral pathogens. It could
adhere well to oral mucosa leading to a prolong existing in oral cavity. And it was a strong antioxidants producer,
which could release the stress condition under oral diseases. Lactobacillus rhamnosus SD11 has also been proven
in clinical trials for having an ability to reduce the level of cariogenic bacteria in oral cavity of subjects after
probiotic consumption.
We believe that our creative innovation will significantly change the perspective of oral prevention. DR.
SAN will give a benefit by improving oral health not only individual but also in general population. Furthermore,
its mass production can affect the dental industry through significant socio-economic benefits.

7. Probiotics: From Selection to Application for Human and Animal Health
Professor Dr. Rawee Teanpaisan
Faculty of Dentistry, Prince of Songkla University, Thailand
rawee.t@psu.ac.th
Probiotics has become highly recognized as supplements for humans and animals because of their
beneficial effects on promoting health and well-being. We have proposed the novel probiotic Lactobacillus strains
derived from human including Lactobacillus paracasei SD1, Lactobacillus rhamnosus SD4, Lactobacillus
rhamnosus SD11 and Lactobacillus fermentum SD7.After strains identifying, the strains have been characterized,
based on the main selection criteria for any potential probiotics. It has shown that Lactobacillus paracasei SD1
and Lactobacillus rhamnosus SD11 exhibit antimicrobial proteins against human and animal pathogens such as
cariogenic mutans streptococci, Streptococcus suis, enteropathogenic Escherichia coli etc. Lactobacillus
fermentum SD7 has high ability for aggregation and Lactobacillus rhamnosus SD4 could adhere well to host cells.
In addition, the selected strains are strong antioxidants producers.
To evaluate the effect of a single probiotic strain in prevention of dental caries, randomized, double-blind,
placebo-controlled trials have been set. It has shown that milk powder contained Lactobacillus paracasei SD1 and
fermented milk contained Lactobacillus rhamnosus SD11 could reduce salivary cariogenic bacteria among volunteers who
received the probiotic products resulting in less caries progression.
Lactobacillus paracasei SD1, Lactobacillus rhamnosus SD4, Lactobacillus rhamnosus SD11 and Lactobacillus
fermentum SD7 in combination were given to piglets from birth. It has revealed that Streptococcus suis and
enteropathogenic Escherichia coli were found to be decreased among piglets those received the probiotic product.
Therefore, Lactobacillus paracasei SD1, Lactobacillus rhamnosus SD4, Lactobacillus rhamnosus SD11 and
Lactobacillus fermentum SD7 exhibit their potential to be useful probiotics for promoting health to human and animal.

8. (Dietary Supplement Product)
Product information
Albupro®
is a high protein nutrition supplement prepared mainly from egg white concentrate.
Ultimately, Albupro®
aims to provide an alternative to conventional sources of protein. The drink
contains balanced nutritional values (mainly proteins) in order to promote the health of the consumer
and can provide benefits such as muscle and bone restoration, digestive tract maintenance and

9. enhancement of the immune system. Not only is Albupro®
designed for normal individuals who want to
add more nutrition to their diet, but it can also be consumed by elders, patients in hospitals and in
recuperation. Moreover, Albupro®
is made entirely of natural ingredients, ensuring quality and safety.
The product is made in powder form and available in three different flavors, including vanilla,
chocolate and strawberry.
Key ingredient
The fundamental ingredient in Albupro®
is egg white or albumen, which has the vital function of
supporting the egg yolk in order to optimize embryo development. It acts as a shock absorber
suspends the yolk in place, constitutes an antimicrobial barrier, and most importantly provides water,
protein and other nutrients to the developing embryo. Thus, it is evident that egg white is an excellent
source of nutrition.
90% of an egg white consists primarily of water, which is effectively used to dissolve the egg
white’s remaining 10% of proteins, including albumins, mucoproteins, and globulins. Albumin is a
major constituent, as it accounts for 54% of an egg white’s total protein content. Unlike the yolk, egg
whites contain almost no fat, and its carbohydrate content is less than 1%. Therefore, it is considered
a high effective and viable source of protein in regards of nutritional purposes.

10. Origin of ingredients
The eggs used in Albupro®
are supplied from farms that have, most of the time, over produced
eggs and therefore causing price reduction. For example, at one particular farm network, some
hundred thousand of eggs are discarded on a daily basis in order to stabilize market prices.
Standard
Rewards
Platinum medal win from Economic and Scientific Innovation INTARG 2016

11. at Poland
Honor of Invention Award from Economic and Scientific Innovation INTARG 2016 at Poland

12. Bioborne Co., Ltd.
Health and beauty are synonymous attributes that sustain and promote one another.
Bioborne’s visions are to research, design and create products that naturally enhance the health and
beauty of our customers. Committed to producing unique products based on natural raw materials
and innovative methods, we aim to promote long-lived beauty, sustainable and healthier lifestyles, as
well as preserve our environment.
Bioborne was incorporated in 1995 and is situated in the heart of Thailand, a country
overflowing with natural resources and organic remedies. Such a plentiful environment has provided
Bioborne with numerous, creative and healthy raw materials to construct our products. Today, we still
have explored innovative ingredients, new technology and novel processes to create products that
will yield optimal, and environmentally friendly results, according to our customers’ needs.
Address
25 Soi Charoen Nakorn 14, Charoen Nakorn Road,
Klongtonsai, Klongsan, Bangkok, Thailand.

13. Contact us
Mr. Noppadol Pongtiwattanakul
Commercial Manager
Tel: +66 (0) 2 861-0660
Mob: +66 (0) 9 2935-6649
Fax: +66 (0) 2 439-4522
Email: sale@bioborne.com
Website: www.bioborne.com

14. “Natural Plant Vaccine for crop protection by physical and biosynthetic barriers with a
unique delivery mechanism”
Mr. Karsidete Teeranitayatarn
Chief Innovation Officer & Co-Founder, Green Innovative Biotechnology Co., Ltd., Thailand
karsidete@gib.co.th
Natural Plant Vaccineis an agricultural innovative-product for increasing the plant innate immune activity
which protects plants from the diseases and various insects as well as enables plant to grow in unfavorable
climates.
The process of plant defense consists of two mechanism including 1. Biosynthetic protection; plants
produce the secondary metabolites such as phenolics and terpenoids that either kill or retard the development of
pathogens and enable plant to grow in unfavorable climates.2.Physical barriers; plants can change their structures
through the formation of a waxy cuticle, thickened cell wall, toughened or hardened leaves as well as increase
trichome density, hardened and length. Both mechanisms can defense against pathogens, insects and enable plant
to grow in unfavorable climates. Natural Plant Vaccine is the functional activated nano vacc-fertiliceutical which
consists of two component groups including stimulant or elicitor and precursor.Natural Plant Vaccine can activate
and induce defense mechanism of plants to decrease the risk of damage of plant production. In addition, Natural
Plant Vaccine can substitute or decrease the use of chemicals, insecticides, and antibiotics and increase both
quantity and quality of the cultivated plants. Importantly, Natural Plant Vaccine can raise the quality of local
produced-plants to meet the export standards.
Our technology is beneficial to human life because it is non-toxic and non-chemical pesticide. Importantly,
the income can be boosted through growing marketing channels and increasing value-added productivity from
better quality and more valuable nutrition products for consumers. It results in improving the quality of life via
food safety, food security and food sustainability which impact on the global economy.