5. Dosage Form
• A dosage form is the physical form in
which a drug is produced and dispensed.
• Example:
– Tablet,
– Capsule,
– PFS (Powder for Suspension)
– Injection
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6. Strength
Amount of the active ingredient is present in
each dosage.
Example:
500mg Tablet
200mg/5ml PFS
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7. Brand Name
Strength
Generic Name
Dosage
Form
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8. COGS
• Cost of Goods sold
• Raw material + Packaging Material + Utility cost
+ Per head cost
TP
•Trade Price
•COGS + Profit
Invoice Price
TP+ VAT
MRP
Maximum Retail Price
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TP+ VAT+ Chemist Profit
10. Bioavailability
• Amount of drug that present in blood after
administration.
• INTRAVENOUS Route- Bioavaiability 100%
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11. Peak Plasma concentration, Cmax
The maximum plasma concentration of the drug
achieved in blood after a dose
Tmax
The time when the
maximum plasma
concentration (Cmax) is
reached.
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12. Plasma half life/
Elimination Half Life, T1/2
Time necessary for the drug to be reduced to
half of its plasma concentration
11
10
9
8
7
6
5
4
3
2
1
0
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17
T1/2
13. Area Under the Curve (AUC)
The area under the plot of plasma concentration of
drug against time after drug administration.
14. MEC
• Minimum Effective Concentration
• The smallest concentration of a drug that will
induce the desired pharmacological effect
MIC
• Minimum inhibitory concentration
• MIC is defined as the minimum
concentration of antibiotic which will inhibit
the growth of the microorganism
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16. First pass effect/ First pass metabolism
The removal of a drug by the liver, before the
drug has become available for use, is called
the first pass effect.
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17. Efficacy
Power or capacity to produce a desired effect
Potency
Amount of drug required to produce a particular
response
Affinity:
Tendency of a drug to combine with receptor
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18. Therapeutic dose
The dose that may be required to produce a
desired effect.
Sub Therapeutic dose
Indicating a dosage of a drug, less than the amount
required for a therapeutic effect.
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