Abstract Summary: ASRA Fifth
Edition Guidelines
• • Hemorrhagic complications from regional
anesthesia are extremely rare.
• • The 5th edition of ASRA’s Evidence-Based
Guidelines (2025) reviews data since 2018.
• • Maintains an 'antihemorrhagic' (patient-
safety first) approach due to limited RCT
evidence.
• • Shifts terminology: 'low dose' and 'high
dose' replace 'prophylactic' and 'therapeutic'

ASRA_5th_Edition_Abstract_Summary copy.pptx

  • 1.
    Abstract Summary: ASRAFifth Edition Guidelines • • Hemorrhagic complications from regional anesthesia are extremely rare. • • The 5th edition of ASRA’s Evidence-Based Guidelines (2025) reviews data since 2018. • • Maintains an 'antihemorrhagic' (patient- safety first) approach due to limited RCT evidence. • • Shifts terminology: 'low dose' and 'high dose' replace 'prophylactic' and 'therapeutic'

Editor's Notes

  • #1  Speaker Notes: - Emphasize the rarity of hemorrhagic complications in regional anesthesia. - Highlight ASRA’s ongoing commitment to patient safety through conservative, evidence-informed approaches. - Explain why randomized trials are impractical for such rare events. - Discuss terminology update from “prophylactic/therapeutic” to “low/high dose” for better clinical accuracy. - Mention the inclusion of drug-specific assays as a new practice tool. - Conclude by noting that each recommendation now specifies its evolution from earlier versions.