The LABVANTAGE architecture provides a scalable and high-performance environment for laboratory information management. It uses a zero-footprint design that allows users to access the system from any device with a web browser. The system's layers include web servers, application servers, database servers, and optional reporting servers. It leverages standard technologies like Java, HTML, and SQL for flexibility and integration. The architecture is designed for reliability, security, and to easily scale for increased user loads through clustering of servers.

1. LABVANTAGE® ARCHITECTURE
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2. DOCUMENT PURPOSE AND SCOPE seamlessly to create a scalable, high-performance
This document provides an overview of the environment. This environment allows multiple
LABVANTAGE architecture, and describes the application servers to perform in a cluster, with the
approach to enabling Internet/Intranet access. It is load balanced across each server. LABVANTAGE also
written for the audience who is familiar with basic leverages standard corporate infrastructures by enabling
Internet and architecture concepts and is intended to the open flow of information between internal and
provide the reader with a general understanding of the external systems, and by enabling the integration of 3rd
LABVANTAGE architecture. party applications.
LABVANTAGE ARCHITECTURE OVERVIEW End User Client(s)
LABVANTAGE has as its foundation a zero footprint LABVANTAGE supports access from any Internet/
architecture that has been developed by LABVANTAGE Intranet devices running Microsoft® Internet Explorer
for almost a decade. This scalable architecture provides 7.0+ on a PC-based operating system. This zero
LABVANTAGE users, both internal and external to installation browser/server architecture greatly simplifies
the laboratory, with the ability to access all authorized enterprise application deployment and administration
functionality within LABVANTAGE from virtually any with no plug-ins, downloads or applets required on the
Internet or Intranet access device. end-user client.
Figure 1 illustrates the components of LABVANTAGE’s Application Server
architecture -- end user client(s), application server(s), The application server hosts the business layer of the
web server(s), database server(s), and reporting LABVANTAGE architecture. Business layer objects are
server(s). The various layers interact and connect written as standard Java EE (formerly J2EE) Enterprise
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3. FIGURE 1: LABVANTAGE Internet Architecture
APPLICATION SERVER APPLICATION SERVER WEB SERVER
▪▪ Clusterable ▪▪ Sybase® EA Server 5.5 ▪▪ Clusterable
▪▪ Java EE Compliant Application Server ▪▪ BEA WebLogic® 10.2 MP2 ▪▪ Request Management
▪▪ Load Balancing ▪▪ IBM WebSphere® 6.1.0.25 ▪▪ Business Link Integration
▪▪ Fault Tolerant ▪▪ Redhat JBoss™ ▪▪ Java EE Compliant
▪▪ Fail Over Application Server
▪▪ Transaction Management 4.3.0.GA CP06 REPORT SERVER
▪▪ Workflow Management Business Objects™ XI R2
▪▪ User Interface Processor
▪▪ Process Scheduling
▪▪ Business Rules Engine
▪▪ Security Management
▪▪ Data Definition Management
▪▪ JDBC Manager
WEB BROWSER
Microsoft® Internet Explorer 7.0+
DATABASE SERVER
BROWSER CLIENTS Oracle® 10g R2/11g R1
▪▪ HTML/JavaScript Microsoft® SQL Server 2005
▪▪ Thin Client PC
▪▪ External System-
XML
▪▪ PDA/Tablets
Java Beans (EJB) and manage all requests for data and the appropriate service. Services may be authentication
services. Using industry standard Java EE development requests, web pages, attachment downloads, reports
techniques, LABVANTAGE can be operated on the or other atomic operations, such as Asynchronous
Sybase® EA Server 5.5, IBM WebSphere® 10.2, the JavaScript and XML (AJAX) requests.
BEA WebLogic® 6.1.0.25, and the Redhat JBoss™
Application Server 4.3.0.GA CP06. Pure HTML LABVANTAGE web pages are generated
using Java Server Pages (JSPs). LABVANTAGE custom
Web Server tags and Java APIs facilitate the generation process
End-user clients communicate with the web server using by communicating directly with the LABVANTAGE
standard HTTP requests via a request controller servlet, application server.
which manages all requests by redirecting control to
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4. FIGURE 2: Meta Data Driven Internet Architecture
INTERPRETS META DATA &
DEFINES META DATA EXECUTES BUSINESS RULES
APPLICATION DESIGNER BROWSER APPLICATION
visualization. Powered by JasperReports, a 100% Java
Database Server solution and shipped with the iReport Designer™ tool,
The LABVANTAGE database is the repository for all LABVANTAGE enables fast design and deployment
LABVANTAGE information, including application data, of both operational and management reports such as:
web-page metadata, and end user data. LABVANTAGE Certificates of Analysis, Stability Study Reports, Sample
can be operated on Oracle® 10g R2 & 11g R1 and Pick Lists, Work Lists, and more. With LABVANTAGE,
Microsoft® SQL Server 2005 databases. no additional report server is required.
The LABVANTAGE Evergreen Solution Designer LABVANTAGE also interfaces with Business Objects™
(Evergreen™) configuration tool provides an XI R2 for the analysis and reporting of data. In this
environment to rapidly create lab- and user-specific option, the BO Report Server hosts the BO software,
configurations without custom software application as well as associated data and programs. For more
programming. The Evergreen metadata is used to drive information about how LABVANTAGE enables decision
the generation of LABVANTAGE web pages at runtime. support, please download the Reporting & Analytics
When Evergreen saves an application object, it saves Brochure.
this definition to the Evergreen metadata repository
within the Database server (see figure 2). Extensibility and Integration
Although LABVANTAGE is a robust, pre-configured
Report Server(s) (Optional) solution out-of-the-box, as configurable-off-the-shelf
LABVANTAGE provides on-demand reporting and data (COTS) software, it is extensible and may be both
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5. Figure 3: LABVANTAGE Clustering Technology
configured and customized via extensions to the data Scalability & Redundancy
model, user interfaces, authentications, and business LABVANTAGE’s scalability can be enhanced through
rules. LABVANTAGE’s extensibility may be achieved clustering of the application servers (see Figure 3).
through: A cluster is a group of application servers that work
together as a single logical server to manage client
▪▪ Configuring the user interface through Evergreen, requests. With clustering, more and more users can be
which also permits tailored presentations to meet a supported without any fall off in performance.
laboratory’s or end user’s unique needs;
▪▪ Extending the LABVANTAGE data model via the Clustering utilizes load balancing, a process that routes
Data Definition Toolkit incorporated into Evergreen, client requests to the “best” (“best” is determined by the
permitting configurable database objects to meet application server’s specific load balancing algorithms)
specific requirements; server within the cluster. With load balancing, overall
▪▪ Authenticating users and securing access to both throughput is scaled out by multiplying the number of
the application and repository data, by integrating users typically supported by a single server by the total
with Lightweight Directory Access Protocol (LDAP1) number of nodes in the cluster. LABVANTAGE achieves
systems; HTTP load balancing by running a cluster of servers,
▪▪ Integrate to other systems or applications (e.g. whether for small clusters (up to 8 nodes) utilizing
authentication and business rules) or write custom Microsoft’s Network Load Balancing (NLB) technology
add-on (i.e., actions) by leveraging LABVANTAGE’s or larger clusters utilizing hardware alternatives for load
rich Java APIs accessible via Web Services. balancing.
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6. Figure 4: Benchmark of LABVANTAGE’s Clustering Performance
Clustering also maximizes LABVANTAGE’s reliability or thick-clients for international users. Put simply,
by eliminating a single point of failure. If one or more LABVANTAGE’s M18N functionality enables it to be end-
servers fail, the cluster automatically, routes future client user specific, rather than server or client specific. This
request to other servers within the cluster, providing greatly increases the speed and reduces the cost of a
virtually no break in service. global LIMS deployment.
For more information regarding LABVANTAGE’s For more information regarding LABVANTAGE’s M18N
scalability and performance, please download the capability, please download the M18N White Paper.
LABVANTAGE Performance White Paper.
Summary
Multinationalization LABVANTAGE’s architecture provides a powerful, low-
LABVANTAGE is the only zero footprint LIMS cost, low-maintenance framework for today’s competitive
that incorporates complete multinationalization laboratory environment, particularly when compared to
(M18N) capabilities. This capability, coupled with web-enabled or web-based implementations, which carry
LABVANTAGE’s zero-footprint architecture, enables a higher cost of deploying applications to a large end-
an organization to deploy a central application server user base. By leveraging standard Internet technologies,
(or cluster) to support languages, time zones, number if provides easy access to disparate data using common
formats, and date conventions across multiple locales, Web browser software. The architecture is scalable,
eliminating the need to provide multiple servers highly reliable and secure.
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or mechanical, including photocopying and recording, for any purpose, without the express written permission of LabVantage Solutions, Inc.
This document is subject to change without notice, and LabVantage does not warrant that the material contained in this document is error-free. If you find any problems with this document, please report
them to LabVantage in writing. LabVantage®, Evergreen Studio™, Evergreen™, LabVantage Solutions Matrix™ and the LabVantage solution icon are trademarks of LabVantage Solutions, Inc. All other
trademarks are property of their respective owners.
This document may contain statements concerning possible functionality for LabVantage software products and technology. LabVantage disclaims any express or implied commitment to deliver
functionality or software unless or until generally commercially available. Any statements of possible future direction are for information purposes only, and LabVantage makes no express or implied
commitments or representations concerning the timing and content of any future functionality or releases.
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