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Approach to
Edema
In Paediatrics
Angel Govekar
Roll No. 25
MBBS IV
DPU, Pune
In Edema, we’ll discuss:
● Physiology
● Causes of Edema
● Approach to Localised Edema
● Approach to Generalized Edema
● Investigations
● Treatment
● Approach
● Summary
Arteriolar end:
Hydrostatic Pressure > Oncotic Pressure =
Fluid passes into the interstitium
Venule end:
Oncotic pressure> Hydrostatic Pressure =
Fluids returns to Capillary Bed
PHYSIOLOGY
PATHOPHYSIOLOGY
Causes of Edema (1)
PITTING EDEMA NON PITTING EDEMA
● Cardiac cause
○ CCF
○ Pericardial effusion
○ RVH
● Renal Cause
○ Nephrotic Syndrome
○ CKD
● Hepatic Cause
○ Liver cirrhosis
● Hypothyroidism
● Filariasis
● DVT
● Cellulitis
Causes of Edema (2)
LOCALISED EDEMA GENERALISED EDEMA (ANASARCA)
● Cellulitis
● Compartment Syndrome
● Lymphedema
● Acute causes
○ allergy
○ vaccine induced
○ drug induced
● Chronic causes
○ renal cause
○ hepatic cause
● Recurrent causes
○ ACE inhibitor induced
angioedema
○ relapse
Causes of
Edema
- According to Pathophysiology -
Approach to Localised Edema
COMMON CAUSES
Approach to Generalised Edema
HISTORY
GENERAL PHYSICAL EXAMINATION
SYSTEMIC EXAMINATION
1. CARDIAC DISEASE
○ Gallop
○ Tachycardia
○ Tachypnoea
○ Inspiratory crackles
○ Hepatomegaly
2. PERICARDIAL EFFUSION
○ Pericardial Rub
○ Muffled heart sounds
○ Jugular venous distension
3. HEPATIC CAUSE
○ Icterus
○ Hepatosplenomegaly
○ Ascites
4. MALNUTRITION
○ Hepatomegaly
INVESTIGATIONS
1. CBC
2. Urine dipstick
3. CXR
4. ECG
5. RFT
6. 24hr Urine Routine & Microscopy
7. LFT
TREATMENT
4. Diuretics like Furosemide
SUMMARY
● Localized edema is commoner than Generalized
● Commonest cause of edema in children:
a. Generalized: Idiopathic nephrotic syndrome
b. Localized: Allergic reaction
● Most children will have a benign diagnosis and self-limited
course.
● General measures for treatment include management of
primary disease, bed rest, Na+ restriction and Diuretic
administration.
● Most reliable index of progression of treatment of edema is
daily alteration of body weight.

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Approach to Edema in Paediatrics.

  • 1. Approach to Edema In Paediatrics Angel Govekar Roll No. 25 MBBS IV DPU, Pune
  • 2. In Edema, we’ll discuss: ● Physiology ● Causes of Edema ● Approach to Localised Edema ● Approach to Generalized Edema ● Investigations ● Treatment ● Approach ● Summary
  • 3. Arteriolar end: Hydrostatic Pressure > Oncotic Pressure = Fluid passes into the interstitium Venule end: Oncotic pressure> Hydrostatic Pressure = Fluids returns to Capillary Bed PHYSIOLOGY
  • 5. Causes of Edema (1) PITTING EDEMA NON PITTING EDEMA ● Cardiac cause ○ CCF ○ Pericardial effusion ○ RVH ● Renal Cause ○ Nephrotic Syndrome ○ CKD ● Hepatic Cause ○ Liver cirrhosis ● Hypothyroidism ● Filariasis ● DVT ● Cellulitis
  • 6. Causes of Edema (2) LOCALISED EDEMA GENERALISED EDEMA (ANASARCA) ● Cellulitis ● Compartment Syndrome ● Lymphedema ● Acute causes ○ allergy ○ vaccine induced ○ drug induced ● Chronic causes ○ renal cause ○ hepatic cause ● Recurrent causes ○ ACE inhibitor induced angioedema ○ relapse
  • 7. Causes of Edema - According to Pathophysiology -
  • 8. Approach to Localised Edema COMMON CAUSES
  • 9.
  • 10. Approach to Generalised Edema HISTORY
  • 11.
  • 13. SYSTEMIC EXAMINATION 1. CARDIAC DISEASE ○ Gallop ○ Tachycardia ○ Tachypnoea ○ Inspiratory crackles ○ Hepatomegaly 2. PERICARDIAL EFFUSION ○ Pericardial Rub ○ Muffled heart sounds ○ Jugular venous distension 3. HEPATIC CAUSE ○ Icterus ○ Hepatosplenomegaly ○ Ascites 4. MALNUTRITION ○ Hepatomegaly
  • 14. INVESTIGATIONS 1. CBC 2. Urine dipstick 3. CXR 4. ECG 5. RFT 6. 24hr Urine Routine & Microscopy 7. LFT
  • 16.
  • 17.
  • 18. SUMMARY ● Localized edema is commoner than Generalized ● Commonest cause of edema in children: a. Generalized: Idiopathic nephrotic syndrome b. Localized: Allergic reaction ● Most children will have a benign diagnosis and self-limited course. ● General measures for treatment include management of primary disease, bed rest, Na+ restriction and Diuretic administration. ● Most reliable index of progression of treatment of edema is daily alteration of body weight.