Anneli Seppälä-Lindroos is a clinical cardiologist specializing in valve diseases and rheumatic heart disease. She has over 25 years of experience in clinical cardiology and research. Currently, she works as a consulting cardiologist at Jilin Heart Hospital in China, focusing on preoperative patients with severe rheumatic heart disease. She is fluent in English, Finnish, and Swedish with experience working in Finland, Norway, China, and research positions in Helsinki.

1. MD ANNELI SEPPÄLÄ-LINDROOS
c/o Lindroos, Otsonkallio 3 F 38, Espoo, Finland 02100
Home: +358408644937 - seppalalindroos@gmail.com
PROFESSIONAL SUMMARY
Clinical Cardiologist with special interest in valve diseases and rheumatic heart
disease (RHD)
a diverse experience in clinical medicine including clinical work at all levels of
medical care
wide experience of clinical cardiology, cardio-metabolic syndrome and pre and post
operative cardiac care
2 years experience of preclinical research in a high level research group
oral presentations in European society for the study of diabetes (EASD) in Brussels
1999 and Jerusalem 2000
oral presentation (accepted) in The 4th International Conference on Prehypertension,
Hypertension and Cardio metabolic Syndrome, Italy 03-06 March 2016 ("Risk
Evaluation and Management of 100 Consecutive Rheumatic Patients Undergoing
Mitral Surgery in Rural China", Anneli Seppälä-Lindroos, MD; Berit Bode Med
Student and Roland Fasol, MD, PhD; Dept of Cardiology and Cardiac Surgery, The
Jilin Heart Hospital, Changchun, China)
Publications:
CO-WRITER in the article "Women's Heart" in the finnish textbook of Cardiology
(Kardiologia, Duodecim, 2007)
1. Epicardial fat, cardiac dimensions, and low-grade inflammation in young adult
monozygotic twins discordant for obesity. Granér M, Seppälä-Lindroos A, Rissanen
A, Hakkarainen A, Lundbom N, Kaprio J, Nieminen MS, Pietiläinen KH. Am J
Cardiol. 2012 May 1;109(9):1295-302. doi: 10.1016/j.amjcard.2011.12.023. Epub
2012 Feb 10. PMID: 22325087 Related citations Select item 19602132
2. Liver fat and lipid oxidation in humans. Kotronen A, Seppälä-Lindroos A,
Vehkavaara S, Bergholm R, Frayn KN, Fielding BA, Yki-Järvinen H. Liver Int. 2009
Oct;29(9):1439-46. doi: 10.1111/j.1478-3231.2009.02076.x. Epub 2009 Jul 7.
PMID: 19602132 Related citations Select item 18765433
3. Intensive lipid lowering with simvastatin and ezetimibe in aortic stenosis.
Rossebø AB, Pedersen TR, Boman K, Brudi P, Chambers JB, Egstrup K, Gerdts E,
Gohlke-Bärwolf C, Holme I, Kesäniemi YA, Malbecq W, Nienaber CA, Ray S,
Skjaerpe T, Wachtell K, Willenheimer R; SEAS Investigators. N Engl J Med. 2008
Sep 25;359(13):1343-56. doi: 10.1056/NEJMoa0804602. Epub 2008 Sep 2. PMID:
18765433 Free Article Related citations Select item 18008059
4. Tissue specificity of insulin resistance in humans: fat in the liver rather than muscle
is associated with features of the metabolic syndrome. Kotronen A, Seppälä-Lindroos
A, Bergholm R, Yki-Järvinen H. Diabetologia. 2008 Jan;51(1):130-8. Epub 2007
Nov 16. PMID: 18008059 Related citations Select item 17895288
5. Effect of liver fat on insulin clearance. Kotronen A, Vehkavaara S, Seppälä-
Lindroos A, Bergholm R, Yki-Järvinen H. Am J Physiol Endocrinol Metab. 2007
Dec;293(6):E1709-15. Epub 2007 Sep 25. PMID: 17895288 Free Article Related
citations Select item 12924536
6. Rosiglitazone in the treatment of HAART-associated lipodystrophy--a randomized
double-blind placebo-controlled study. Sutinen J, Häkkinen AM, Westerbacka J,
Seppälä-Lindroos A, Vehkavaara S, Halavaara J, Järvinen A, Ristola M, Yki-Järvinen
H. Antivir Ther. 2003 Jun;8(3):199-207. PMID: 12924536 Related citations Select
item 12409740
7. Increased fat accumulation in the liver in HIV-infected patients with antiretroviral
therapy-associated lipodystrophy. Sutinen J, Häkkinen AM, Westerbacka J, Seppälä-

2. Lindroos A, Vehkavaara S, Halavaara J, Järvinen A, Ristola M, Yki-Järvinen H. AIDS.
2002 Nov 8;16(16):2183-93. PMID: 12409740 Related citations Select item
12112939
8. Elevated fasting insulin concentrations associate with impaired insulin signaling
in skeletal muscle of healthy subjects independent of obesity. Korsheninnikova E,
Seppälä-Lindroos A, Vehkavaara S, Goto T, Virkamäki A. Diabetes Metab Res Rev.
2002 May-Jun;18(3):209-16. PMID: 12112939 Related citations Select item
12107194
9. Fat accumulation in the liver is associated with defects in insulin suppression of
glucose production and serum free fatty acids independent of obesity in normal men.
Seppälä-Lindroos A, Vehkavaara S, Häkkinen AM, Goto T, Westerbacka J, Sovijärvi
A, Halavaara J, Yki-Järvinen H. J Clin Endocrinol Metab. 2002 Jul;87(7):3023-8.
PMID: 12107194 Related citations Select item 11701689
10. Resistance to acute insulin induced decreases in large artery stiffness
accompanies the insulin resistance syndrome. Westerbacka J, Seppälä-Lindroos A,
Yki-Järvinen H. J Clin Endocrinol Metab. 2001 Nov;86(11):5262-8. PMID:
11701689 Related citations Select item 11574417
11. Intramyocellular lipid is associated with resistance to in vivo insulin actions on
glucose uptake, antilipolysis, and early insulin signaling pathways in human
skeletal muscle. Virkamäki A, Korsheninnikova E, Seppälä-Lindroos A, Vehkavaara
S, Goto T, Halavaara J, Häkkinen AM, Yki-Järvinen H. Diabetes. 2001
Oct;50(10):2337-43. PMID: 11574417 Free Article Related citations Select item
11238539
12. Insulin sensitivity regulates autonomic control of heart rate variation
independent of body weight in normal subjects. Bergholm R, Westerbacka J,
Vehkavaara S, Seppälä-Lindroos A, Goto T, Yki-Järvinen H. J Clin Endocrinol Metab.
2001 Mar;86(3):1403-9. PMID: 11238539 Related citations Select item 10942737
13. Endothelial dysfunction in men with small LDL particles. Vakkilainen J,
Mäkimattila S, Seppälä-Lindroos A, Vehkavaara S, Lahdenperä S, Groop PH,
Taskinen MR, Yki-Järvinen H. Circulation. 2000 Aug 15;102(7):716-21. PMID:
10942737 Free Article Related citations Select item 10587842
14. In vivo endothelial dysfunction characterizes patients with impaired fasting
glucose. Vehkavaara S, Seppälä-Lindroos A, Westerbacka J, Groop PH, Yki-Järvinen
H. Diabetes Care. 1999 Dec;22(12):2055-60. PMID: 10587842 Free Article
SKILLS
Fluent in english
Fluent in finnish
Fluent in swedish
Basic german and norwegian
Humane and respectful
Culturally sensitive
Conflict resolution ability
Strong interpersonal skills
Compassionate professional
Calm under pressure
Dedicated to excellence
Good clinical judgment
Practiced in cardiovascular disease
Good skills in echocardiography (TTE)
Good skills in clinical cardiology
Good understanding of type 2 diabetes
2015 7 months experience on severe
(preoperative) rheumatic heart disease
(RHD)
WORK HISTORY
06/2015 to Current Consulting Cardiologist
Jilin Heart Hospital – Changchun China
Ordered and executed diagnostic tests and analyzed diagnostic images to further
investigate patient conditions.
Advised and educated patients regarding diet, hygiene and effective disease
prevention methods.

3. Managed, directed and coordinated activities of nurses, assistants, specialists,
residents and other medical staff.
Performed daily echocardiography examinations (TTE) for preoperative valve patients
(>50 severe rheumatic heart disease patients)
Consulting cardiologist at Jilin Heart Hospital Cardial surgery ward (2) 1 Jun
2015-31 Dec 2015
Consulting cardiologist at Jilin Heart Hospital Imaging Department and OR
(echocardiographies TTE, TEE)
04/2004 to Current Consulting Cardiologist
Plus Heath LTD (Plusterveys Oy) – Malmin asematie 6, 00750 Helsinki, Finland
Consulting cardiologist in out patient clinics in public hospitals in the City of
Helsinki and Kouvola
Consulting cardiologist in Kotka Medical Center (Private Medical Service
Company) (Shareholder) (CEO Dr juha Tasa, tel +35852111555)
Consulting cardiologist Mehiläinen (Ambea)
Plus health: tel +3589351040
09/2003 to 10/2004Registrar in cardiology
Helsinki University Hospital (HUCH) – Helsinki Finland
specialist training in cardiology including TTE, permanent pacemaker implantation
(independently, >70 patients), Holter analysis etc.
http://www.med.helsinki.fi/ammatillinen_jatkokoulutus/docs/erikoistumiskoulutus
/erikoislaakari/lokikirjat/lokikirja%202012%20kardiologia.pdf (LOG BOOK IN
CARDIOLOGY TRAINING IN FINLAND)
01/2003 to 09/2003Specialist in internal medicine (cardiology)
Kotka Central Hospital – Kotka Finland
Specialist in Internal medicine
Consultant in Cardiology Ward and CCU for acute cardiac patients in local district
(covering 200 000 inhabitants)
Out patient work (echocardiography, holter, clinical exercise tests)
TTE's
Permanent pacemaker implantation (independent), both single and dual lead devices
08/2001 to 12/2001Consulting Internist
Helsinki University Hospital – Dept. of Internal medicine, Helsinki Finland
Consulting internist in the department of Eating disorders
Cardiac and other clinical problems of anorectic, bulimic, binge eating patients
01/2001 to 06/2001Consulting internist
Helsinki University Hospital (HUCH) – Womens Hospital, Helsinki
Consulting internist in OPD and wards of womens hospital
Treatment of gestational diabetes and hypertension
Treatment of gestation thyroid problems
07/2001 to 07/2001Consulting Internist
Lofoten sykehus – Lofoten Island, Norway
consulting internist in OPD and ICU
01/1999 to 12/2000Clinical Investigator
Helsinki University Hospital (HUCH) – Helsinki Finland
Preclinical reasearch in the Department of Endocrinology (Professor Hannele
Yki-Järvinen's group)
See puplications
08/1996 to 08/1998Registrar in internal medicine
Helsinki University Hospital (HUCH) – Helsinki Finland
p
06/1992 to 07/1996Registrar in internal medicine

4. Kotka Central Hospital – Kotka Finland
Internal medicine department 4.5 yrs
Imaging department 0.5 yrs
01/1991 to 05/1992 General practitioner
The City of Hamina (Fredrikshamn) – Hamina Finland
03/1990 to 05/1990Senior medical assistant
The City of Kotka – Kotka Finland
06/1988 to 06/1988Junior medical assistant
Kuopio University Hospital (KUH) – Kuopio Finland
Department of ORL (oto-rhino-laryngology)
06/1987 to 06/1987Junior medical assistant
Helsinki University Hospital (HUCH) – Helsinki Finland
Jr medical assistant in cardio-thoracic surgery ward and OR
EDUCATION
1982 High School Diploma:
Karjalan Yhteiskoulu (Co-educational School) - Helsinki Finland
1990 M.D.:
Kuopio University - Kuopio Finland
1992 M.D.:
Registered Medical Doctor -
1998 Specialist in Internal Medicine:
Helsinki University - Helsinki Finland
2004 Specialist in Cardiology:
Helsinki University - Helsinki Finland