Discussion about different types of Aneurysm, details about Abdominal aorta aneurysm and brief discussion about some important peripheral aneurysms.
Includes approach to different forms of Abdominal aortic aneurysm, its management and complications related to the surgery.
2. INTRODUCTION
• The term ANEURYSM is derived from the Greek word ANEURYSMA
meaning “ a widening”.
• Normal arterial diameter is dependent on age , gender, body size
and other factors.
• An Aneurysm is defined as a localized dilation at least 50 % larger
than an adjacent normal portion of the same artery.
• ECTASIA- Arterial dilation less than 50% above normal
• ARTERIOMEGALY– Diffuse arterial enlargement involving several
arterial segments with an increase in diameter greater than 50%
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5. PSEUDOANEURYSM
Injury to wall of vessel allows blood to escape from vessel into
adjacent tissue.
Extravasated blood coagulates and becomes a mass along side the
vessel.
This mass of blood (hematoma) gives the impression that there is
an aneurysm
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9. BASED ON MORPHOLOGY
FUSIFORM:
SYMMETRICAL CIRCUMFERENTIAL ENLARGEMENT INVOLVING
ALL LAYERS OF THE ARTERY WALL.
SACCULAR:
ANEURYSMAL DEGENERATION AFFECTING ONLY PART OF THE
ARTERIAL CIRCUMFERENCE.
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11. ABDOMINAL AORTIC ANEURYSM
INCIDENCE: 2% TO 5% OF ALL MEN OVER 60 YRS
COMMON IN MEN ABOVE 60YRS
PEAK OF 5% AT 80 YRS IN MEN
PEAK OF 4.5% AT 90 YRS IN WOMEN
GREATER - FIRST DEGREE RELATIVES
TALLER INDIVIDUAL
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12. Risk Factors
Atherosclerosis (90%)
-Smoking
-Hyperlipidemia
- Diabetes
Gender
- Males > Females
Age
Familial History
- 20% of patients with AA have 1st Degree relative
Connective tissue disease
- Marfan Syndrome- defect in Fibrillin structure
- Ehlers-Danlos - defect in pro-collagen type 3
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15. AAA Sequelae
Natural history :
- gradual and/or sporadic expansion
- accumulation of mural thrombus
Complications
- rupture
- thromboembolic events
- compression of adjacent structures
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16. Progression of AAA
Pathological changes cause the aorta wall to
- become thinner
- bulge
- rupture
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17. AAA ANNUAL RUPTURE RISK 17
American Association for Vascular Surgery and Society for
Vascular Surgery
18. Risk of rupture of an abdominal aortic aneurysm
(AAA) over time according to the first measurement
of aneurysm diameter in 1792 men and 465 women.
The risk of rupture increased markedly in aneurysms
larger than 5.5 cm in diameter
18
Powell, JT, Greenhalgh, RM, N Engl J Med 2003; 348:1895
19. CLINICAL PRESENTATION
AAA are asymptomatic before rupture in 75%
Abdominal palpation may show a pulsatile abdominal mass.
Vague abdominal and back discomfort.
Large aneurysms – GI symptoms– early satiety and vomiting.
Inflammatory aneurysms- pain /fever /ureteral obstruction
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23. USG
most useful and least expensive mode of diagnosis.
Measuring transverse aneurysmal diameter.
Screening /Surveillance/ follow up after endovascular repair.
- Best used to assess progression of AAA size
- Average expansion of 0.4cm/year
Can’t detect Rupture.
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24. CT Imaging
Precise test – provides good images of aorta , aortic lumen branch
vessels and adjacent retroperitoneal structures.
Shows size and extent of aneurysm and relation to renal and iliac
arteries.
SPIRAL CT – 3 dimensional image.
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26. MRI/ MR ANGIOGRAPHY
Useful for planning and follow up of endovascular repair.
Less sensitive than CT scan in identifying accessory renal
arteries.
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27. 27
Chaikof EL, Dalman RL, Eskandari MK, et al. The Society for Vascular Surgery practice guidelines on the care of patients with an abdominal aortic aneurysm. J Vasc
Surg 2018; 67:2.
30. Indications
The AAA diameter is greater than 5.5 cm in diameter in men. In
women, it might be considered from a smaller diameter (5.0 cm)
The patient with AAA is symptomatic
The AAA is rapidly expanding (more than 1 cm/year) irrespective of
the absolute diameter
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33. ENDOVASCULAR REPAIR
TRANSLUMINAL PLACEMENT OF A GRAFT WITHIN THE
ANEURYSM THAT COMPLETELY EXCLUDES THE SAC
FROM GENERAL CIRCULATION
INTRODUCTED BY PARODI IN 1990
SUCCESS RATE 98 %
CONVERTION RATE 12 %
OVERALL HOSPITAL MORTALITY < 2.5 %
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34. Benefits
Theoretical
- Reduced complications and mortality
- Decreased hospitalization
-Decreased cost
Realized
- Same number of complications but different types
- Less systemic complications, same mortality
- Shorter respiratory support
- Decreased ICU and hospital stay
-Decreased blood loss
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35. DISADVANTAGES
CUSTOMISED FOR EACH PATIENT
FOLLOW UP IS CRUCIAL
LONG TERM IMPLICATIONS AWAITED
ENDOLEAK 14 – 20 %
CONTRAST INDUCED NEPHROPATHY
HIGH COST
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38. Complications of EAAA repair
Injuries to arteries of access – Iliac/ Supra Renal
Embolization - micro – Renal Failure
- distal – Ischemia
Procedure related: Groin hematoma, wound infection, Post-
implantation syndrome
Device related : Migration, detachment, rupture, stenosis, kinking,
endoleak
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39. Endoleaks
Leak around proximal or distal attachment sites
Persistent flow in aneurysm sac
Risks :
- Expansion
-Rupture
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40. 40
Chaikof EL, Blankensteijn JD, Harris PL, et al. Reporting standards for endovascular aortic aneurysm repair. J
Vasc Surg 2002; 35:1048
41. RUPTURED AAA
anteriorly into the peritoneal cavity (20%) or postero-laterally into
the retroperitoneal space (80%) causing Retroperitoneal hematoma
Less than 50% of patients with rupture survive to reach hospital.
C/F:
“Classic triad:”
-Severe abdominal pain -Hypotension -Pulsatile mass
Less common symptoms:
-Groin/flank pain, hematuria, groin hernia all secondary to
increased intra-abdominal pressure
- Congestive Heart Failure with JVD and abdominal bruit if patient
has ruptured into the Vena Cava
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42. Rupture outcomes
Operative mortality: 50%
Combined Mortality(Community + Hospital) : 80-90 %
More than one third of rupture cases die outside the hospital
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43. AAA - RUPTURE
• Treatment
A) EMERGENCY SURGERY : First successful repair of a ruptured AAA
was by Cooley and DeBakey in 1954
• More than 98% of ruptures occur below the renal arteries.
• Exploration -- through MIDLINE incision
IF aorta approached at infra renal level– it should be clamped
PROXIMAL CONTROL– At the level of diaphragm
• OTHER METHODS : Compression at diaphragm
Placement of aortic balloon catheters
Foley catheters via puncture of the aneurysm
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44. THORACO ABDOMINAL AORTIC
Aneurysms that involve the thoracic and abdominal aorta or those
aneurysms including the visceral aortic segments
Etiology: - degenerative– 80%
- sequelae of chronic dissection– 20%
C/f-- sudden development of severe pain– back /epigastric/flank
pain
others– hoarseness/cough hemoptysis /dysphagia lusoria
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45. Crawford classification
Type I – involves Descending thoracic aorta and abdominal aorta
proximal to renal arteries.
Type II – Most of DTA + AA distal to renal arteries
Type III – Involves aorta distal to renal arteries.
Type IV – Involves all or most of the abdominal aorta including the
Para visceral segment.
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46. SYPHILITIC ANEURYSM
Seen in tertiary stage of syphilis with obliterative endarteritis of
vasa vasorum and aortitis
Roughening of intima : “Tree barking”
Involves the thoracic aorta
Complications include rupture, aortic insufficiency, and narrowing
of coronary ostia
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48. FEMORAL ANEURYSM
Common peripheral aneurysm
Incidence- 7.39 / 1OOOOO Population
TRUE aneurysm- Non specific etiology
FALSE aneurysm - anastomotic/traumatic catheter-
induced/infected
TYPE 1 – Limited to Common Femoral Artery
TYPE 2 – Involving orifice of Profunda Femoris artery
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49. Femoral aneurysm
Asymptomatic with pulsatile mass
Local pain – pressure on adjacent nerve
Limb edema/venous distention- venous compression
Lower extremity ischemia with intermittent claudication /rest
pain/gangrene
COMPLICATIONS -THROMBOSIS
- RUPTURE
- EMBOLIZATION
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50. OPERATIVE MANAGEMENT
TYPE 1 ANEURYSM:
- INTERPOSITION GRAFT OF DACRON
- e PTFE
TYPE 2 ANEURYSM:
-INTERPOSITION GRAFT TO SFA/ PFA with re-implantation
of the other artery.
- SYNDACTYLIZATION- Suturing of Superficial and Profunda
femoris arteries together to form a common lumen
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51. POPLITEAL ANEURYSM
commonest ( 70% )
65% bilateral with 25% associated with AAA
Etiology related to chronic flexion/extension
Associated aneurysms – other leg, femoral, aortic
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52. Clinical features-
-Swelling in popliteal region which is smooth, soft ,
pulsatile , well localized, warm compressible , often with thrill and
bruit.
- thrombosis and emboli can cause distal gangrene
- rupture : torrential hemorrhage
Treatment- ANEURYSMORRHAPHY- Repair with arterial graft using
PTFE, dacron
- ENDOLUMINAL STENTING
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53. National Institute for Health and Care Excellence (NICE) in the UK
published guidelines in 2020 recommending open surgical repair
unless contraindicated, reserving EVAR for high-risk patients or
those with a hostile abdomen.
This compares to the European Society for Vascular Surgery 2019
guidelines, which recommend EVAR as the first-line treatment
option with open surgical repair to be considered for patients with
long life expectancy.
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* Typically identified by abdominal ultrasound obtained to evaluate palpable abdominal mass, for screening purposes, or follow-up evaluation of another identified aneurysm (eg, thoracic aortic aneurysm, popliteal artery aneurysm). AAA has also been identified incidentally on plain abdominal radiography, spine imaging studies, and others.
* Permissive hypotension targets systolic BP 80 to 100 mmHg.¶ Intravenous contrast is not absolutely required to diagnose rupture but is highly desired if endovascular repair is an option.Δ Ultrasound can be performed at the bedside or in the operating room. In a patient with an appropriate history and clinical findings, ultrasound may not be necessary.◊ In the absence of overt rupture, no radiologic signs have been proven to predict AAA rupture for certain, but signs associated with impending AAA rupture have included: crescent sign, layering hematoma, aortic blebs, aortic draping over a vertebral body, irregular aortic wall, breaks in calcification of the aortic wall, and localized areas of higher attenuation within mural thrombus. In combination with an AAA of >5 cm, these signs may indicate a rapidly changing aneurysm and urgency for repair.§ The aneurysm is managed as with other asymptomatic AAA.¥ For patients with symptomatic (ruptured, nonruptured) AAA, an endovascular first approach is generally preferred if anatomically suitable and institutional resources, endovascular devices, and expertise are available. Otherwise, open surgical repair can be performed.‡ Initial wire access and aortic occlusion balloon placement can precede repair as a temporizing measure to limit bleeding.† Obtain CT angiography, if contrast study not previously performed.
Post-implantation syndrome (PIS) was initially registered as a fever and leucocytosis syndrome following the implantation of a stent graft in the aorta. The etiology of PIS is due to the attribution of endovascular reconstruction to the systemic inflammatory reaction.
The types of endoleaks after an endovascular repair of an abdominal aortic aneurysm are as follows:Type I is due to an incompetent seal at the proximal (Ia) or distal (Ib) attachment site.
Type II results from flow into and out of the aneurysm sac from one or more patent branch vessels (lumbar or inferior mesenteric artery).
Type III results from dissociation of modular components.
Type IV is due to leaks through the porous graft material.
Endoleak of undefined origin (type V) is continued aneurysm sac expansion without a demonstrable endoleak on any imaging modality. It is also referred to as endotension
Dysphagia lusoria :
aberrant right subclavian artery
(ARSA) that compresses the esophagus.