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1. The document is a letter from Kevin W. Sharer, Chairman and CEO of Amgen Inc., informing stockholders about the upcoming Annual Meeting of Stockholders on May 11, 2005. 2. At the Annual Meeting, stockholders will vote on electing three directors, ratifying the selection of the independent accountants, and three stockholder proposals. 3. The Board recommends voting for the election of directors and ratification of the accountants, and against the three stockholder proposals. Stockholders are urged to vote by proxy, mail, internet or telephone in advance of the meeting.











































