This poster presents guidelines for researchers to improve reproducibility in scientific research by better documenting the key entities of research: data, software, workflow, and research output. It recommends documenting data sources and processing steps, writing descriptive code with examples, and using tools like Docker, Jupyter notebooks, LaTeX, and data repositories to capture the experimental environment and research process. Following these guidelines helps researchers communicate and verify their work, allowing others to build on their research findings.
Are you interesting in offering data management services at your library but aren’t sure where to start? Then this class is for you! During this session, we will
• Outline the data management topics that are commonly offered in libraries
• Present strategies for how to determine what services might be most useful on your campus and create synergistic partnerships with other university entities
• Dive into how to offer support with data management plans
• Present a case study for using an institutional repository to archive and share research data
• Identify additional training opportunities and open educational resources you can use to develop robust DM services
The class will consist of a mix of presentations, hands on activities, and discussion. So come ready to participate!
Datat and donuts: how to write a data management planC. Tobin Magle
Good data management practices are becoming increasingly important in the digital age. Because we now have the technology to freely share research data and also because funding agencies want to do more with decreasing research funds, many funding agencies and journals require authors and grantees to share their research data. To provide training in this area, Tobin Magle, the Morgan Library's Cyberinfrastructure Facilitator, is putting on a series of data management workshops called "Data and Donuts". The first session of Data and Donuts will discuss the importance of data management and how to write a data management plan.
This session covers topics related to data archiving and sharing. This includes data formats, metadata, controlled vocabularies, preservation, archiving and repositories.
Are you interesting in offering data management services at your library but aren’t sure where to start? Then this class is for you! During this session, we will
• Outline the data management topics that are commonly offered in libraries
• Present strategies for how to determine what services might be most useful on your campus and create synergistic partnerships with other university entities
• Dive into how to offer support with data management plans
• Present a case study for using an institutional repository to archive and share research data
• Identify additional training opportunities and open educational resources you can use to develop robust DM services
The class will consist of a mix of presentations, hands on activities, and discussion. So come ready to participate!
Datat and donuts: how to write a data management planC. Tobin Magle
Good data management practices are becoming increasingly important in the digital age. Because we now have the technology to freely share research data and also because funding agencies want to do more with decreasing research funds, many funding agencies and journals require authors and grantees to share their research data. To provide training in this area, Tobin Magle, the Morgan Library's Cyberinfrastructure Facilitator, is putting on a series of data management workshops called "Data and Donuts". The first session of Data and Donuts will discuss the importance of data management and how to write a data management plan.
This session covers topics related to data archiving and sharing. This includes data formats, metadata, controlled vocabularies, preservation, archiving and repositories.
The metadata about scientific experiments are crucial for finding, reproducing, and reusing the data that the metadata describe. We present a study of the quality of the metadata stored in BioSample—a repository of metadata about samples used in biomedical experiments managed by the U.S. National Center for Biomedical Technology Information (NCBI). We tested whether 6.6 million BioSample metadata records are populated with values that fulfill the stated requirements for such values. Our study revealed multiple anomalies in the analyzed metadata. The BioSample metadata field names and their values are not standardized or controlled—15% of the metadata fields use field names not specified in the BioSample data dictionary. Only 9 out of 452 BioSample-specified fields ordinarily require ontology terms as values, and the quality of these controlled fields is better than that of uncontrolled ones, as even simple binary or numeric fields are often populated with inadequate values of different data types (e.g., only 27% of Boolean values are valid). Overall, the metadata in BioSample reveal that there is a lack of principled mechanisms to enforce and validate metadata requirements. The aberrancies in the metadata are likely to impede search and secondary use of the associated datasets.
Research Data Management for Qualitative ResearchersCelia Emmelhainz
This presentation reviews concerns with research data management (RDM) specific to qualitative researchers such as sociologists and anthropologists. Presented to the qualitative methods working group in the D-Lab at UC Berkeley.
Profiling systems have achieved notable adoption by research institutions.1 Multi-site search of research profiling systems has substantially evolved since the first deployment of systems such as DIRECT2Experts.2 CTSAsearch is a federated search engine using VIVO-compliant Linked Open Data (LOD) published by members of the NIH-funded Clinical and Translational Science (CTSA) consortium and other interested parties. Sixty-four institutions are currently included, spanning six distinct platforms and three continents (North America, Europe and Australia). In aggregate, CTSAsearch has data on 150-300 thousand unique researchers and their 10 million publications. The public interface is available at http://research.icts.uiowa.edu/polyglot.
The Center for Expanded Data Annotation and Retrieval (CEDAR) has developed a suite of tools and services that allow scientists to create and publish metadata describing scientific experiments. Using these tools and services—referred to collectively as the CEDAR Workbench—scientists can collaboratively author metadata and submit them to public repositories. A key focus of our software is semantically enriching metadata with ontology terms. The system combines emerging technologies, such as JSON-LD and graph databases, with modern software development technologies, such as microservices and container platforms. The result is a suite of user-friendly, Web-based tools and REST APIs that provide a versatile end-to-end solution to the problems of metadata authoring and management. This talk presents the architecture of the CEDAR Workbench and focuses on the technology choices made to construct an easily usable, open system that allows users to create and publish semantically enriched metadata in standard Web formats.
The availability of high-quality metadata is key to facilitating discovery in the large variety of scientific datasets that are increasingly becoming publicly available. However, despite the recent focus on metadata, the diversity of metadata representation formats and the poor support for semantic markup typically result in metadata that are of poor quality. There is a pressing need for a metadata representation format that provides strong interoperation capabilities together with robust semantic underpinnings. In this talk, we describe such a format, together with open-source Web-based tools that support the acquisition, search, and management of metadata. We outline an initial evaluation using metadata from a variety of biomedical repositories.
What is reproducible research? Why should I use it? what tools should I use? This session will show you how to use scripts, version control and markdown to do better research.
Presentation on the use of the Eureka Research Workbench to store data and scientific workflow information. Presented online as part of the Dial-a-molecule 'Liberating Laboratory Data' event (http://www.dial-a-molecule.org/wp/events-listing/liberating-laboratory-data/)
The metadata about scientific experiments are crucial for finding, reproducing, and reusing the data that the metadata describe. We present a study of the quality of the metadata stored in BioSample—a repository of metadata about samples used in biomedical experiments managed by the U.S. National Center for Biomedical Technology Information (NCBI). We tested whether 6.6 million BioSample metadata records are populated with values that fulfill the stated requirements for such values. Our study revealed multiple anomalies in the analyzed metadata. The BioSample metadata field names and their values are not standardized or controlled—15% of the metadata fields use field names not specified in the BioSample data dictionary. Only 9 out of 452 BioSample-specified fields ordinarily require ontology terms as values, and the quality of these controlled fields is better than that of uncontrolled ones, as even simple binary or numeric fields are often populated with inadequate values of different data types (e.g., only 27% of Boolean values are valid). Overall, the metadata in BioSample reveal that there is a lack of principled mechanisms to enforce and validate metadata requirements. The aberrancies in the metadata are likely to impede search and secondary use of the associated datasets.
Research Data Management for Qualitative ResearchersCelia Emmelhainz
This presentation reviews concerns with research data management (RDM) specific to qualitative researchers such as sociologists and anthropologists. Presented to the qualitative methods working group in the D-Lab at UC Berkeley.
Profiling systems have achieved notable adoption by research institutions.1 Multi-site search of research profiling systems has substantially evolved since the first deployment of systems such as DIRECT2Experts.2 CTSAsearch is a federated search engine using VIVO-compliant Linked Open Data (LOD) published by members of the NIH-funded Clinical and Translational Science (CTSA) consortium and other interested parties. Sixty-four institutions are currently included, spanning six distinct platforms and three continents (North America, Europe and Australia). In aggregate, CTSAsearch has data on 150-300 thousand unique researchers and their 10 million publications. The public interface is available at http://research.icts.uiowa.edu/polyglot.
The Center for Expanded Data Annotation and Retrieval (CEDAR) has developed a suite of tools and services that allow scientists to create and publish metadata describing scientific experiments. Using these tools and services—referred to collectively as the CEDAR Workbench—scientists can collaboratively author metadata and submit them to public repositories. A key focus of our software is semantically enriching metadata with ontology terms. The system combines emerging technologies, such as JSON-LD and graph databases, with modern software development technologies, such as microservices and container platforms. The result is a suite of user-friendly, Web-based tools and REST APIs that provide a versatile end-to-end solution to the problems of metadata authoring and management. This talk presents the architecture of the CEDAR Workbench and focuses on the technology choices made to construct an easily usable, open system that allows users to create and publish semantically enriched metadata in standard Web formats.
The availability of high-quality metadata is key to facilitating discovery in the large variety of scientific datasets that are increasingly becoming publicly available. However, despite the recent focus on metadata, the diversity of metadata representation formats and the poor support for semantic markup typically result in metadata that are of poor quality. There is a pressing need for a metadata representation format that provides strong interoperation capabilities together with robust semantic underpinnings. In this talk, we describe such a format, together with open-source Web-based tools that support the acquisition, search, and management of metadata. We outline an initial evaluation using metadata from a variety of biomedical repositories.
What is reproducible research? Why should I use it? what tools should I use? This session will show you how to use scripts, version control and markdown to do better research.
Presentation on the use of the Eureka Research Workbench to store data and scientific workflow information. Presented online as part of the Dial-a-molecule 'Liberating Laboratory Data' event (http://www.dial-a-molecule.org/wp/events-listing/liberating-laboratory-data/)
Research Data (and Software) Management at Imperial: (Everything you need to ...Sarah Anna Stewart
A presentation on research data management tools, workflows and best practices at Imperial College London with a focus on software management. Presented at the 2017 session of the HPC Summer School (Dept. of Computing).
It is about:
Introduction: What Is “Research Data”? and Data Lifecycle
Part 1:
Why Manage Your Data?
Formatting and organizing the data
Storage and Security of Data
Data documentation and meta data
Quality Control
Version controlling
Working with sensitive data
Controlled Vocabulary
Centralized Data Management
Part 2:
Data sharing
What are publishers & funders saying about data sharing?
Researchers’ Attitudes
Benefits of data sharing
Considerations before data sharing
Methods of Data Sharing
Shared Data Uses and Its’ Limitations
Data management plans
Brief summary
Acknowledgment , References
For a Bioinformatics Discussion for Students and Post-Docs (BioDSP) meeting: Expands on Sandve's "Ten Simple Rules for Reproducible Computational Research"
Presentation slides on Open Science and research reproducibility. Presented by Gareth Knight (LSHTM Research Data Manager) on 18th September 2018, as part of an Open Science event for LSHTM Week 2018.
A Maturing Role of Workflows in the Presence of Heterogenous Computing Archit...Ilkay Altintas, Ph.D.
cientific workflows are used by many scientific communities to capture, automate and standardize computational and data practices in science. Workflow-based automation is often achieved through a craft that combines people, process, computational and Big Data platforms, application-specific purpose and programmability, leading to provenance-aware archival and publications of the results. This talk summarizes varying and changing requirements for distributed workflows influenced by Big Data and heterogeneous computing architectures and present a methodology for workflow-driven science based on these maturing requirements.
Keynote: SemSci 2017: Enabling Open Semantic Science
1st International Workshop co-located with ISWC 2017, October 2017, Vienna, Austria,
https://semsci.github.io/semSci2017/
Abstract
We have all grown up with the research article and article collections (let’s call them libraries) as the prime means of scientific discourse. But research output is more than just the rhetorical narrative. The experimental methods, computational codes, data, algorithms, workflows, Standard Operating Procedures, samples and so on are the objects of research that enable reuse and reproduction of scientific experiments, and they too need to be examined and exchanged as research knowledge.
We can think of “Research Objects” as different types and as packages all the components of an investigation. If we stop thinking of publishing papers and start thinking of releasing Research Objects (software), then scholar exchange is a new game: ROs and their content evolve; they are multi-authored and their authorship evolves; they are a mix of virtual and embedded, and so on.
But first, some baby steps before we get carried away with a new vision of scholarly communication. Many journals (e.g. eLife, F1000, Elsevier) are just figuring out how to package together the supplementary materials of a paper. Data catalogues are figuring out how to virtually package multiple datasets scattered across many repositories to keep the integrated experimental context.
Research Objects [1] (http://researchobject.org/) is a framework by which the many, nested and contributed components of research can be packaged together in a systematic way, and their context, provenance and relationships richly described. The brave new world of containerisation provides the containers and Linked Data provides the metadata framework for the container manifest construction and profiles. It’s not just theory, but also in practice with examples in Systems Biology modelling, Bioinformatics computational workflows, and Health Informatics data exchange. I’ll talk about why and how we got here, the framework and examples, and what we need to do.
[1] Sean Bechhofer, Iain Buchan, David De Roure, Paolo Missier, John Ainsworth, Jiten Bhagat, Philip Couch, Don Cruickshank, Mark Delderfield, Ian Dunlop, Matthew Gamble, Danius Michaelides, Stuart Owen, David Newman, Shoaib Sufi, Carole Goble, Why linked data is not enough for scientists, In Future Generation Computer Systems, Volume 29, Issue 2, 2013, Pages 599-611, ISSN 0167-739X, https://doi.org/10.1016/j.future.2011.08.004
Short overview responding to the following 4 questions, as suggested by the RDA Long Tail Data IG:
1. Name and location of institution/service
2. What type of data do you collect and how do you acquire the data?
3. What services do you provide?
4. How do you intend to interoperate with a global ecosystem of research data?
Amit Sheth with TK Prasad, "Semantic Technologies for Big Science and Astrophysics", Invited Plenary Presentation, at Earthcube Solar-Terrestrial End-User Workshop, NJIT, Newark, NJ, August 13, 2014.
Like many other fields of Big Science, Astrophysics and Solar Physics deal with the challenges of Big Data, including Volume, Variety, Velocity, and Veracity. There is already significant work on handling volume related challenges, including the use of high performance computing. In this talk, we will mainly focus on other challenges from the perspective of collaborative sharing and reuse of broad variety of data created by multiple stakeholders, large and small, along with tools that offer semantic variants of search, browsing, integration and discovery capabilities. We will borrow examples of tools and capabilities from state of the art work in supporting physicists (including astrophysicists) [1], life sciences [2], material sciences [3], and describe the role of semantics and semantic technologies that make these capabilities possible or easier to realize. This applied and practice oriented talk will complement more vision oriented counterparts [4].
[1] Science Web-based Interactive Semantic Environment: http://sciencewise.info/
[2] NCBO Bioportal: http://bioportal.bioontology.org/ , Kno.e.sis’s work on Semantic Web for Healthcare and Life Sciences: http://knoesis.org/amit/hcls
[3] MaterialWays (a Materials Genome Initiative related project): http://wiki.knoesis.org/index.php/MaterialWays
[4] From Big Data to Smart Data: http://wiki.knoesis.org/index.php/Smart_Data
This was presented in Internet Archive Jan 22, 2016. It demonstrates the possible types of stories and how to manually create them from Archive-It collections.
This pdf is about the Schizophrenia.
For more details visit on YouTube; @SELF-EXPLANATORY;
https://www.youtube.com/channel/UCAiarMZDNhe1A3Rnpr_WkzA/videos
Thanks...!
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
Seminar of U.V. Spectroscopy by SAMIR PANDASAMIR PANDA
Spectroscopy is a branch of science dealing the study of interaction of electromagnetic radiation with matter.
Ultraviolet-visible spectroscopy refers to absorption spectroscopy or reflect spectroscopy in the UV-VIS spectral region.
Ultraviolet-visible spectroscopy is an analytical method that can measure the amount of light received by the analyte.
Earliest Galaxies in the JADES Origins Field: Luminosity Function and Cosmic ...Sérgio Sacani
We characterize the earliest galaxy population in the JADES Origins Field (JOF), the deepest
imaging field observed with JWST. We make use of the ancillary Hubble optical images (5 filters
spanning 0.4−0.9µm) and novel JWST images with 14 filters spanning 0.8−5µm, including 7 mediumband filters, and reaching total exposure times of up to 46 hours per filter. We combine all our data
at > 2.3µm to construct an ultradeep image, reaching as deep as ≈ 31.4 AB mag in the stack and
30.3-31.0 AB mag (5σ, r = 0.1” circular aperture) in individual filters. We measure photometric
redshifts and use robust selection criteria to identify a sample of eight galaxy candidates at redshifts
z = 11.5 − 15. These objects show compact half-light radii of R1/2 ∼ 50 − 200pc, stellar masses of
M⋆ ∼ 107−108M⊙, and star-formation rates of SFR ∼ 0.1−1 M⊙ yr−1
. Our search finds no candidates
at 15 < z < 20, placing upper limits at these redshifts. We develop a forward modeling approach to
infer the properties of the evolving luminosity function without binning in redshift or luminosity that
marginalizes over the photometric redshift uncertainty of our candidate galaxies and incorporates the
impact of non-detections. We find a z = 12 luminosity function in good agreement with prior results,
and that the luminosity function normalization and UV luminosity density decline by a factor of ∼ 2.5
from z = 12 to z = 14. We discuss the possible implications of our results in the context of theoretical
models for evolution of the dark matter halo mass function.
Cancer cell metabolism: special Reference to Lactate PathwayAADYARAJPANDEY1
Normal Cell Metabolism:
Cellular respiration describes the series of steps that cells use to break down sugar and other chemicals to get the energy we need to function.
Energy is stored in the bonds of glucose and when glucose is broken down, much of that energy is released.
Cell utilize energy in the form of ATP.
The first step of respiration is called glycolysis. In a series of steps, glycolysis breaks glucose into two smaller molecules - a chemical called pyruvate. A small amount of ATP is formed during this process.
Most healthy cells continue the breakdown in a second process, called the Kreb's cycle. The Kreb's cycle allows cells to “burn” the pyruvates made in glycolysis to get more ATP.
The last step in the breakdown of glucose is called oxidative phosphorylation (Ox-Phos).
It takes place in specialized cell structures called mitochondria. This process produces a large amount of ATP. Importantly, cells need oxygen to complete oxidative phosphorylation.
If a cell completes only glycolysis, only 2 molecules of ATP are made per glucose. However, if the cell completes the entire respiration process (glycolysis - Kreb's - oxidative phosphorylation), about 36 molecules of ATP are created, giving it much more energy to use.
IN CANCER CELL:
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
Unlike healthy cells that "burn" the entire molecule of sugar to capture a large amount of energy as ATP, cancer cells are wasteful.
Cancer cells only partially break down sugar molecules. They overuse the first step of respiration, glycolysis. They frequently do not complete the second step, oxidative phosphorylation.
This results in only 2 molecules of ATP per each glucose molecule instead of the 36 or so ATPs healthy cells gain. As a result, cancer cells need to use a lot more sugar molecules to get enough energy to survive.
introduction to WARBERG PHENOMENA:
WARBURG EFFECT Usually, cancer cells are highly glycolytic (glucose addiction) and take up more glucose than do normal cells from outside.
Otto Heinrich Warburg (; 8 October 1883 – 1 August 1970) In 1931 was awarded the Nobel Prize in Physiology for his "discovery of the nature and mode of action of the respiratory enzyme.
WARNBURG EFFECT : cancer cells under aerobic (well-oxygenated) conditions to metabolize glucose to lactate (aerobic glycolysis) is known as the Warburg effect. Warburg made the observation that tumor slices consume glucose and secrete lactate at a higher rate than normal tissues.
Richard's aventures in two entangled wonderlandsRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Richard's entangled aventures in wonderlandRichard Gill
Since the loophole-free Bell experiments of 2020 and the Nobel prizes in physics of 2022, critics of Bell's work have retreated to the fortress of super-determinism. Now, super-determinism is a derogatory word - it just means "determinism". Palmer, Hance and Hossenfelder argue that quantum mechanics and determinism are not incompatible, using a sophisticated mathematical construction based on a subtle thinning of allowed states and measurements in quantum mechanics, such that what is left appears to make Bell's argument fail, without altering the empirical predictions of quantum mechanics. I think however that it is a smoke screen, and the slogan "lost in math" comes to my mind. I will discuss some other recent disproofs of Bell's theorem using the language of causality based on causal graphs. Causal thinking is also central to law and justice. I will mention surprising connections to my work on serial killer nurse cases, in particular the Dutch case of Lucia de Berk and the current UK case of Lucy Letby.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
1. www.postersession.com
Reproducibility in research is the ability to replicate the ultimate product of academic
research to reproduce the results and build on the research. The main entities of academic
research are data, scripts/software for processing and analysis, workflow of the research
process, and research output (Figure 1). Documenting workflow, data, and code during the
active phase of the scientific research is important for communication of the scholarship and
replication of the results. When researchers submit scientific papers or build on their work,
they face the challenge of having to remember all the details of their own work if they
haven't included well documentation for this work. In order to sustain and ensure the
integrity of reproducibility in the scientific research and advance the scientific research
process, this poster presents guidelines for researchers that help them to manage the
research entities during the active phase of the research process.
A Guide for Reproducible Research
Yasmin AlNoamany
University of California, Berkeley
yasminal@berkeley.edu
Introduction
The main entities of the scientific research
Research Software – source code or executables that researchers generate or integrate
into the workflow of the scientific research.
What to document:
Good practices in managing your software:
• Custom scripts to automate research analysis.
• Attach examples of how the code works.
• Generate a list of all scripts, how to run them, and in what order.
• Use tools that capture the experimental environment, such as Docker and ReproZIP.
• Use metadata standards for each generated module. Each module should have at least
the following:
Ø Name of the module
Ø Name of the project
Ø Name of Author
Ø Input and Output
Ø Purpose of the Module
Ø A brief Description
Naming files should be descriptive and consistent!
Tools
• Docker
• Apache Ivy
Research Software
• The experimental environment – e.g.,
hardware, operating system
• The computing platform and
prerequisites
• Scripts and libraries
• Input and output parameters
• The functionality of each script
• Dependencies of the software
indicating versions
• The structure of the code/software and
details about individual components
Scientific paper(s) along with graphs/tables – document(s) that contains the results of
the scientific research as well as all the assorted graphs and tables. This could be:
• Compiled files (e.g., pdf)
• Source files (e.g., .tex files, figures, .bib file)
• Packages/libraries/styles installed (e.g., graphics)
• Graphs and tables
Good practices in managing output files:
• Document the environment and the file structure.
• Track versions of produced papers, graphs, etc.
• Document any problem that faces you with the computing environment.
• Backup your files every while.
• Save your files on Dropbox or any other cloud storage to keep track of your
versions.
• For writing your manuscript, use Latex and Bibtex for these reasons:
Ø Latex is free and open source.
Ø A .tex file can be edited in any text editor.
Ø The content is separated from style.
Ø With a couple of line and style files, you can convert how your pdf looks.
Ø Latex allows preserving your files longer time.
Ø The output document looks better.
Naming files should be descriptive and consistent!
Tools
• Latex
• Bibtex
Research Output
Data
Data – files that were used or produced during the scientific research process. These files
can be raw data or different versions of processed data.
Good practices in managing data:
• Include a README file in the directory that has the data.
• Write a data management plan, which has become a requirement by funding agencies.
• Provide a detailed description of the data, data source(s), and how it will be used.
• Provide a description to the process of capturing the data.
• Describe all the steps of data preprocessing.
• Provide a description and information about each new version of the data.
• Provide details about the software/code that is used for preprocessing the data.
• Adapt metadata standards for describing the data.
• Backup your files every while.
Naming files should be descriptive and consistent!
Tools
• DMPTool
• DASH
• Figshare
• EZID
• Box and Drive
• Merritt repository
Source: http://data-archive.ac.uk/create-manage/life-cycle
References
1. AlNoamany, Yasmin. "How to make your research reproducible”, http://guides.lib.berkeley.edu/reproducibility-guide,
(2017).
2. Stodden, Victoria. "Enabling reproducible research: Open licensing for scientific innovation." (2009).
3. Bailey, David H., Jonathan M. Borwein, and Victoria Stodden. "Facilitating reproducibility in scientific computing:
Principles and practice." Reproducibility: Principles, Problems, Practices, and Prospects (2014): 205-232.
4. Stodden, Victoria, et al. "Enhancing reproducibility for computational methods." Science 354.6317 (2016): 1240-1241.
Workflow
Workflow documentation – detailed steps of the workflow
that capture the process of the scientific research.
• Weekly/daily notes on the project's stages
• Documentation for the steps of the workflow
For managing the research workflow, document:
• The steps of the research starting from the design till
fetching the data till producing graphs and tables in the
scientific output.
• All adopted libraries and integrated algorithms.
• All citations and information of code and data used.
• The input and the output of each step.
Electronic Notebooks, such as Jupyter help documenting the workflow!
Tools
• Jupyter
• knitr
• Overleaf
• ShareLatex
• GitHub
• Zenodo
Sponsored in part through grants from the Alfred P. Sloan Foundation #G-2014-13746 and from the National Science
Foundation NSF ACI #1349002