M.P. Ramachandran is the promoter, chairman and managing director of Jyothy Laboratories, India's fifth largest FMCG business. He started the company in 1983 with Rs. 40,000 and it now has a market capitalization of over USD 350 million. Ramachandran acquired Henkel India, gaining its brands like Pril, Margo and Henko, in a deal that drew some criticism but which he believes was right for the companies. The acquisition makes Jyothy a larger player but it also takes on Rs. 400 crore in debt and a new major competitor in Hindustan Unilever. Ramachandran remains committed to the brands he helped build and says Jyothy
Este guión de docente describe una lección de 90 minutos sobre los pueblos originarios de Chile para estudiantes de segundo básico. Los estudiantes aprenderán sobre los modos de vida y expresiones culturales actuales de los pueblos mapuche, aimara y rapa nui mediante la creación de un power point. Primero introducirán el tema y luego investigarán en internet para desarrollar un power point sobre el pueblo designado (mapuche, aimara o rapa nui) enfocándose en su modo de vida actual, tradiciones y costumbres. Final
El documento describe un plan de dos clases para enseñar sobre los pueblos originarios del norte de Chile. En la primera clase, los estudiantes trabajarán en parejas para crear una presentación en PowerPoint sobre la ubicación geográfica, organización social, económica, vivienda, religión y lenguaje de un pueblo originario designado. En la segunda clase, las parejas presentarán sus presentaciones al curso y completarán una evaluación individual.
Troponinas estratificación de riesgo síndromes coronarios agudos (SCA)Julián Vega Adauy
Este documento discute la estratificación de riesgo en síndromes coronarios agudos utilizando marcadores de daño miocárdico, en particular las troponinas. Explica que las troponinas son un marcador independiente de riesgo de mortalidad y eventos, y que niveles elevados se asocian con mayor riesgo independientemente del score de riesgo utilizado. Finalmente, enfatiza la importancia de realizar una estratificación de riesgo temprana y objetiva en los pacientes, basada en scores validados e integración clínica
Transgenderism and Gender Pluralism in Southeast Asian Historymrace89
This document summarizes an article about the historical presence and changing status of transgender communities in Southeast Asia. It describes how gender pluralism and ritual transgender roles were traditionally accepted but have faced increasing stigma and discrimination with the rise of state power, westernization, and an emphasis on "Asian values" promoting heteronormativity. Key transgender roles like the Bissu in Indonesia have been stripped of status and legitimacy over time. The conclusion questions whether religious transgender communities should have to change their beliefs to conform to modern norms.
IKSL provides low-cost mobile services to empower rural farmers in India with relevant information. It uses push technologies like voice messages and pull technologies like helplines to deliver agricultural information from sources like IFFCO and universities to farmers. It partners with organizations like Commonwealth of Learning to develop content. Success stories show how individual farmers and women's groups have improved incomes and living standards by implementing the information received from IKSL. Surveys found over 70% of farmers find the messages useful and more than half depend on IKSL as their sole information source. In 2010-11, IKSL reached over 4 million customers across 18 states and 10 languages.
M.P. Ramachandran is the promoter, chairman and managing director of Jyothy Laboratories, India's fifth largest FMCG business. He started the company in 1983 with Rs. 40,000 and it now has a market capitalization of over USD 350 million. Ramachandran acquired Henkel India, gaining its brands like Pril, Margo and Henko, in a deal that drew some criticism but which he believes was right for the companies. The acquisition makes Jyothy a larger player but it also takes on Rs. 400 crore in debt and a new major competitor in Hindustan Unilever. Ramachandran remains committed to the brands he helped build and says Jyothy
Este guión de docente describe una lección de 90 minutos sobre los pueblos originarios de Chile para estudiantes de segundo básico. Los estudiantes aprenderán sobre los modos de vida y expresiones culturales actuales de los pueblos mapuche, aimara y rapa nui mediante la creación de un power point. Primero introducirán el tema y luego investigarán en internet para desarrollar un power point sobre el pueblo designado (mapuche, aimara o rapa nui) enfocándose en su modo de vida actual, tradiciones y costumbres. Final
El documento describe un plan de dos clases para enseñar sobre los pueblos originarios del norte de Chile. En la primera clase, los estudiantes trabajarán en parejas para crear una presentación en PowerPoint sobre la ubicación geográfica, organización social, económica, vivienda, religión y lenguaje de un pueblo originario designado. En la segunda clase, las parejas presentarán sus presentaciones al curso y completarán una evaluación individual.
Troponinas estratificación de riesgo síndromes coronarios agudos (SCA)Julián Vega Adauy
Este documento discute la estratificación de riesgo en síndromes coronarios agudos utilizando marcadores de daño miocárdico, en particular las troponinas. Explica que las troponinas son un marcador independiente de riesgo de mortalidad y eventos, y que niveles elevados se asocian con mayor riesgo independientemente del score de riesgo utilizado. Finalmente, enfatiza la importancia de realizar una estratificación de riesgo temprana y objetiva en los pacientes, basada en scores validados e integración clínica
Transgenderism and Gender Pluralism in Southeast Asian Historymrace89
This document summarizes an article about the historical presence and changing status of transgender communities in Southeast Asia. It describes how gender pluralism and ritual transgender roles were traditionally accepted but have faced increasing stigma and discrimination with the rise of state power, westernization, and an emphasis on "Asian values" promoting heteronormativity. Key transgender roles like the Bissu in Indonesia have been stripped of status and legitimacy over time. The conclusion questions whether religious transgender communities should have to change their beliefs to conform to modern norms.
IKSL provides low-cost mobile services to empower rural farmers in India with relevant information. It uses push technologies like voice messages and pull technologies like helplines to deliver agricultural information from sources like IFFCO and universities to farmers. It partners with organizations like Commonwealth of Learning to develop content. Success stories show how individual farmers and women's groups have improved incomes and living standards by implementing the information received from IKSL. Surveys found over 70% of farmers find the messages useful and more than half depend on IKSL as their sole information source. In 2010-11, IKSL reached over 4 million customers across 18 states and 10 languages.
Dokumen tersebut membahas tentang akuntabilitas pengadaan barang dan jasa teknologi informasi di Badan Pengawasan Keuangan dan Pembangunan (BPKP). Dokumen tersebut menjelaskan definisi akuntabilitas dan pengadaan, analisis lingkungan birokrasi pengadaan, titik kritis pengadaan TI, struktur pengadaan, dan kesalahan persepsi terkait pengadaan TI.
This 1 page document lists years from 1902 to 1961 in different formats, with some years grouped together or separated by dashes. It does not provide any other context or details about the meaning or purpose of the listed years.
El documento describe los criterios de evaluación de una asignatura. Se dividirá la calificación de la siguiente manera: 10% de evaluación continua a través de interrogatorios, simposios y presentaciones; 5% de un examen de prácticas; 85% de cinco exámenes de conocimientos sobre diferentes capítulos, más un examen final sobre todos los capítulos que representa el 40% de la calificación.
Este documento describe los criterios y tipos de vegetación en Ecuador según las características climáticas, edáficas, topográficas y florísticas. Explica las diferentes formaciones vegetales como bosques, matorrales, páramos y sabanas que se presentan en las regiones naturales de la Costa, Sierra y Amazonía del país. Además, identifica los pisos florísticos y formaciones vegetales específicas que se encuentran en cada una de las subregiones del Ecuador.
Decreto comite cultura arte transmilenioAndrés Borges
Este decreto crea el Comité Cultura y Arte Transmilenio en Bogotá con el objetivo de mejorar la cultura ciudadana y el comportamiento social en el sistema de transporte masivo. El comité se reunirá mensualmente y estará compuesto por funcionarios del distrito y autoridades locales. Entre sus funciones están establecer estrategias para promover la cultura, evaluar el comportamiento social, y presentar informes al consejo local de seguridad.
Grupos musicales favoritos incluyen Bob Marley, Beyoncé y Rihana. Los programas de televisión preferidos son MTV, Fox Sports y Telehit. La película favorita es Rápido y Furioso 4 y los principales actores son Vin Diesel, Paul Walker, Jordana Brewsler y Michelle Rodríguez.
Este documento presenta una unidad didáctica de 180 minutos dividida en dos clases sobre los pueblos originarios del sur de Chile. Los estudiantes trabajarán en parejas para crear un powerpoint con información sobre la ubicación, organización social, economía, vivienda, religión y lenguaje de un pueblo asignado, el cual presentarán al final de la segunda clase.
Nirupama Menon Rao is the current Indian Ambassador to the United States. She had a distinguished career in the Indian Foreign Service, becoming the first female ambassador to China. She received her education in languages and literature, graduating with honors from Mount Carmel College. She then topped the civil service exam and joined the Indian Foreign Service. Over her career, she held several important diplomatic positions and helped evacuate Indians from Libya during the crisis. She has received honors for her contributions and continues to write on India's international relations.
La ingeniería de software trata de sistematizar el proceso de desarrollo de software mediante técnicas que han demostrado reducir el riesgo de fracaso. Cubre todas las fases del ciclo de vida de sistemas de información y es aplicable a muchas áreas como negocios, ciencia, medicina y más. Aunque no existe una definición precisa, se describe generalmente como la aplicación de principios y métodos de ingeniería para desarrollar software de manera rentable y fiable.
The document discusses LASIK eye surgery and answers common questions about the procedure. It explains that LASIK is a refractive surgery used to correct vision problems and there are different types, with bladeless LASIK having the best results. It outlines eligibility, the standard pre-and post-surgery process, possible side effects and complications, and discusses undercorrection or overcorrection and how they would be addressed. It also notes that results are generally permanent but vision can deteriorate with age or disease. Contact information and pricing for LASIK packages are provided at the end.
Dokumen tersebut membahas tentang akuntabilitas pengadaan barang dan jasa teknologi informasi di Badan Pengawasan Keuangan dan Pembangunan (BPKP). Dokumen tersebut menjelaskan definisi akuntabilitas dan pengadaan, analisis lingkungan birokrasi pengadaan, titik kritis pengadaan TI, struktur pengadaan, dan kesalahan persepsi terkait pengadaan TI.
This 1 page document lists years from 1902 to 1961 in different formats, with some years grouped together or separated by dashes. It does not provide any other context or details about the meaning or purpose of the listed years.
El documento describe los criterios de evaluación de una asignatura. Se dividirá la calificación de la siguiente manera: 10% de evaluación continua a través de interrogatorios, simposios y presentaciones; 5% de un examen de prácticas; 85% de cinco exámenes de conocimientos sobre diferentes capítulos, más un examen final sobre todos los capítulos que representa el 40% de la calificación.
Este documento describe los criterios y tipos de vegetación en Ecuador según las características climáticas, edáficas, topográficas y florísticas. Explica las diferentes formaciones vegetales como bosques, matorrales, páramos y sabanas que se presentan en las regiones naturales de la Costa, Sierra y Amazonía del país. Además, identifica los pisos florísticos y formaciones vegetales específicas que se encuentran en cada una de las subregiones del Ecuador.
Decreto comite cultura arte transmilenioAndrés Borges
Este decreto crea el Comité Cultura y Arte Transmilenio en Bogotá con el objetivo de mejorar la cultura ciudadana y el comportamiento social en el sistema de transporte masivo. El comité se reunirá mensualmente y estará compuesto por funcionarios del distrito y autoridades locales. Entre sus funciones están establecer estrategias para promover la cultura, evaluar el comportamiento social, y presentar informes al consejo local de seguridad.
Grupos musicales favoritos incluyen Bob Marley, Beyoncé y Rihana. Los programas de televisión preferidos son MTV, Fox Sports y Telehit. La película favorita es Rápido y Furioso 4 y los principales actores son Vin Diesel, Paul Walker, Jordana Brewsler y Michelle Rodríguez.
Este documento presenta una unidad didáctica de 180 minutos dividida en dos clases sobre los pueblos originarios del sur de Chile. Los estudiantes trabajarán en parejas para crear un powerpoint con información sobre la ubicación, organización social, economía, vivienda, religión y lenguaje de un pueblo asignado, el cual presentarán al final de la segunda clase.
Nirupama Menon Rao is the current Indian Ambassador to the United States. She had a distinguished career in the Indian Foreign Service, becoming the first female ambassador to China. She received her education in languages and literature, graduating with honors from Mount Carmel College. She then topped the civil service exam and joined the Indian Foreign Service. Over her career, she held several important diplomatic positions and helped evacuate Indians from Libya during the crisis. She has received honors for her contributions and continues to write on India's international relations.
La ingeniería de software trata de sistematizar el proceso de desarrollo de software mediante técnicas que han demostrado reducir el riesgo de fracaso. Cubre todas las fases del ciclo de vida de sistemas de información y es aplicable a muchas áreas como negocios, ciencia, medicina y más. Aunque no existe una definición precisa, se describe generalmente como la aplicación de principios y métodos de ingeniería para desarrollar software de manera rentable y fiable.
The document discusses LASIK eye surgery and answers common questions about the procedure. It explains that LASIK is a refractive surgery used to correct vision problems and there are different types, with bladeless LASIK having the best results. It outlines eligibility, the standard pre-and post-surgery process, possible side effects and complications, and discusses undercorrection or overcorrection and how they would be addressed. It also notes that results are generally permanent but vision can deteriorate with age or disease. Contact information and pricing for LASIK packages are provided at the end.
Pictorial and detailed description of patellar instability with sign and symptoms and how to diagnose , what investigations you should go with and how to approach with treatment options . I have presented this slide in my 2nd year junior residency in orthopedics at LLRM medical college Meerut and got good reviews for it
After getting it read you will definitely understand the topic.
Osvaldo Bernardo Muchanga-GASTROINTESTINAL INFECTIONS AND GASTRITIS-2024.pdfOsvaldo Bernardo Muchanga
GASTROINTESTINAL INFECTIONS AND GASTRITIS
Osvaldo Bernardo Muchanga
Gastrointestinal Infections
GASTROINTESTINAL INFECTIONS result from the ingestion of pathogens that cause infections at the level of this tract, generally being transmitted by food, water and hands contaminated by microorganisms such as E. coli, Salmonella, Shigella, Vibrio cholerae, Campylobacter, Staphylococcus, Rotavirus among others that are generally contained in feces, thus configuring a FECAL-ORAL type of transmission.
Among the factors that lead to the occurrence of gastrointestinal infections are the hygienic and sanitary deficiencies that characterize our markets and other places where raw or cooked food is sold, poor environmental sanitation in communities, deficiencies in water treatment (or in the process of its plumbing), risky hygienic-sanitary habits (not washing hands after major and/or minor needs), among others.
These are generally consequences (signs and symptoms) resulting from gastrointestinal infections: diarrhea, vomiting, fever and malaise, among others.
The treatment consists of replacing lost liquids and electrolytes (drinking drinking water and other recommended liquids, including consumption of juicy fruits such as papayas, apples, pears, among others that contain water in their composition).
To prevent this, it is necessary to promote health education, improve the hygienic-sanitary conditions of markets and communities in general as a way of promoting, preserving and prolonging PUBLIC HEALTH.
Gastritis and Gastric Health
Gastric Health is one of the most relevant concerns in human health, with gastrointestinal infections being among the main illnesses that affect humans.
Among gastric problems, we have GASTRITIS AND GASTRIC ULCERS as the main public health problems. Gastritis and gastric ulcers normally result from inflammation and corrosion of the walls of the stomach (gastric mucosa) and are generally associated (caused) by the bacterium Helicobacter pylor, which, according to the literature, this bacterium settles on these walls (of the stomach) and starts to release urease that ends up altering the normal pH of the stomach (acid), which leads to inflammation and corrosion of the mucous membranes and consequent gastritis or ulcers, respectively.
In addition to bacterial infections, gastritis and gastric ulcers are associated with several factors, with emphasis on prolonged fasting, chemical substances including drugs, alcohol, foods with strong seasonings including chilli, which ends up causing inflammation of the stomach walls and/or corrosion. of the same, resulting in the appearance of wounds and consequent gastritis or ulcers, respectively.
Among patients with gastritis and/or ulcers, one of the dilemmas is associated with the foods to consume in order to minimize the sensation of pain and discomfort.
The biomechanics of running involves the study of the mechanical principles underlying running movements. It includes the analysis of the running gait cycle, which consists of the stance phase (foot contact to push-off) and the swing phase (foot lift-off to next contact). Key aspects include kinematics (joint angles and movements, stride length and frequency) and kinetics (forces involved in running, including ground reaction and muscle forces). Understanding these factors helps in improving running performance, optimizing technique, and preventing injuries.
Breast cancer: Post menopausal endocrine therapyDr. Sumit KUMAR
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
Diagnosis and Staging
The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
NAVIGATING THE HORIZONS OF TIME LAPSE EMBRYO MONITORING.pdfRahul Sen
Time-lapse embryo monitoring is an advanced imaging technique used in IVF to continuously observe embryo development. It captures high-resolution images at regular intervals, allowing embryologists to select the most viable embryos for transfer based on detailed growth patterns. This technology enhances embryo selection, potentially increasing pregnancy success rates.
STUDIES IN SUPPORT OF SPECIAL POPULATIONS: GERIATRICS E7shruti jagirdar
Unit 4: MRA 103T Regulatory affairs
This guideline is directed principally toward new Molecular Entities that are
likely to have significant use in the elderly, either because the disease intended
to be treated is characteristically a disease of aging ( e.g., Alzheimer's disease) or
because the population to be treated is known to include substantial numbers of
geriatric patients (e.g., hypertension).
Summer is a time for fun in the sun, but the heat and humidity can also wreak havoc on your skin. From itchy rashes to unwanted pigmentation, several skin conditions become more prevalent during these warmer months.
Nano-gold for Cancer Therapy chemistry investigatory projectSIVAVINAYAKPK
chemistry investigatory project
The development of nanogold-based cancer therapy could revolutionize oncology by providing a more targeted, less invasive treatment option. This project contributes to the growing body of research aimed at harnessing nanotechnology for medical applications, paving the way for future clinical trials and potential commercial applications.
Cancer remains one of the leading causes of death worldwide, prompting the need for innovative treatment methods. Nanotechnology offers promising new approaches, including the use of gold nanoparticles (nanogold) for targeted cancer therapy. Nanogold particles possess unique physical and chemical properties that make them suitable for drug delivery, imaging, and photothermal therapy.
Travel vaccination in Manchester offers comprehensive immunization services for individuals planning international trips. Expert healthcare providers administer vaccines tailored to your destination, ensuring you stay protected against various diseases. Conveniently located clinics and flexible appointment options make it easy to get the necessary shots before your journey. Stay healthy and travel with confidence by getting vaccinated in Manchester. Visit us: www.nxhealthcare.co.uk