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a de novo mutation in the CACNAID gene cause autism spectrum disorder and epilepsy.
this gene codes for a Ca2+ channel that function as a monomer. at the molecular level,
the mutation is a missense mutation in the channel protein that causes increased Ca2+
entry into the cell compared to the wild type channels.

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a de novo mutation in the CACNAID gene cause autism spectrum disorder.docx

  • 1. a de novo mutation in the CACNAID gene cause autism spectrum disorder and epilepsy. this gene codes for a Ca2+ channel that function as a monomer. at the molecular level, the mutation is a missense mutation in the channel protein that causes increased Ca2+ entry into the cell compared to the wild type channels.