The Schwann cells of myelinated axon in PNS form myelin sheath around the axon
In the unmyelinated axon a Schwann cell supports several axons without forming myelin sheath
Schwann cells have a basal lamina
5. The Neuron Cell Body
Large basophilic cell body
Abundant RER called Nissl bodies in cell
body & dendrites but absent in axon
Large nucleus with euchromatin &
prominent nucleolus
Neurons do not divide
6.
7.
8. Types of Neurons
According to the number of processes arising from
the cell body:-
1. Bipolar:-
Two processes (olfactory epithelium)
2. Multipolar:-
More than two processes (e.g. sympathetic ganglia)
3. Pseudounipolar:-
One process dividing into two (e.g. spinal ganglia)
9.
10. Types of Axons
1. Myelinated axon (with myelin sheath)
may be sensory or motor
2. Unmyelinated axon (without myelin
sheath) may be sensory or motor
All types of axons in PNS are supported by
cells called Schwann cells
11. Schwann Cells
The Schwann cells of myelinated axon in
PNS form myelin sheath around the axon
In the unmyelinated axon a Schwann cell
supports several axons without forming
myelin sheath
Schwann cells have a basal lamina
12. 1. Myelinated Axon
1.Each Schwann cell forms one segment of
myelin sheath around the axon called
internode
2.Each internode is about 200-1000 μm long
3.Between internodes is a gap called node of
Ranvier where there is no myelin sheath
13. What Is Myelin Sheath
Myelin sheath is concentric layers of the
Schwann cell membrane around the axon
It contains the lipids & proteins of the cell
membrane of the Schwann cell
17. 2. Umyelinated Axons
Successive Schwann cells surround the
axon without forming myelin sheath
Many axons are found in deep grooves on
the surface of a single Schwann cell
They are smaller than myelinated axons
18.
19. Structure of Peripheral Nerve
Contains parallel bundles of axons
Each bundle contains myelinated &
umyleinated axons
Contains motor & sensory axons
Mo nerve cell bodies
20. Connective Tissue of the Nerve
Epineurium:- external layer of dense
irregular CT covering the nerve
Perineurium:- layers of flat cells with tight
junctions & basal lamina around each
bundle of axons
Endoneurium:- innermost layer of reticular
CT around each Schwann cell covering the
axon
21.
22.
23.
24. Ganglia
Ganglia are groups of neuron cell bodies
outside the CNS
Types of ganglia:-
1. Dorsal root (spinal) ganglia
2. Autonomic ganglia (e.g. Sympathetic
ganglia)
25.
26. 1. Dorsal Root Ganglion
(Spinal Ganglion)
Contains pseudounipolar neurons in groups
Each neuron is surrounded by a capsule of
supporting cells called satellite cells
Contains myelinated axons
Sensory ganglion
27.
28. Sympathetic Ganglion
Contains multipolar neurons separated by
spaces containing unmyelinated axons
Capsule of satellite cells is not prominent
It is a motor ganglion
Contains synapses