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7- The following is a generic monomer used in DNA synthesis- Label the.docx

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7. The following is a generic monomer used in DNA synthesis. Label the following parts of the monomer. a. The protecting group that is removed to create a nucleophilic alcohol (deprotection step). b. The leaving group that will be displaced (coupling step). c. The oxygen, that if unreacted will be capped (capping step). d. The phosphorus that will be oxidized (oxidation step). 3. What is the phosphorous oxidation state (III or V) in the above monomer? Does this make it more or less reactive than the form found naturally in DNA/RNA? .

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7. The following is a generic monomer used in DNA synthesis. Label the following parts of the monomer. a. The protecting group that is removed to create a nucleophilic alcohol (deprotection step). b. The leaving group that will be displaced (coupling step). c. The oxygen, that if unreacted will be capped (capping step). d. The phosphorus that will be oxidized (oxidation step). 3. What is the phosphorous oxidation state (III or V) in the above monomer? Does this make it more or less reactive than the form found naturally in DNA/RNA?

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