Bed bugs can be difficult to detect due to their small size and tendency to hide. This document provides guidance on inspecting for bed bugs in various locations like hotels, homes, and transportation. It outlines signs of infestation to look for, including rust-colored spots, fecal stains, shed skins, and a sweet odor. High-risk hiding places that should be thoroughly inspected include mattress and box spring seams, headboards, furniture, curtains, and any clutter around beds or sleeping areas. A complete inspection can take 1-2 hours.