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STEPS IN PRECLINICAL
RESEARCH
Disease-related
genomics
Target
Identification
Lead
discovery
Potential Drug
Candidate
Preclinical Study
Models and Phases
Investigational New
Drug Application
6
6
in vitro
in vivo
ex vivo
in silico model
2
3 4
5
6
Toxicity, Safety,
Dosing, Treatment
Response Assessment
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6 Steps in Preclinical Research