The major maternal health problems include unwanted pregnancy and unsafe abortion, problems related to pregnancy and childbirth, harmful traditional practices, violence against women, HIV/AIDS and STIs, cancers of the reproductive organs, and malnutrition. These problems persist due to factors operating at multiple levels, including households and communities, the health system, and public policies. Overcoming these problems requires a lifecycle approach to women's health, empowering women, improving access to reproductive healthcare and contraception, preventing violence and harmful practices, and ensuring good nutrition.