This document discusses techniques for optimizing Plone performance. It summarizes three customer cases and their different Plone implementations. The key areas discussed for optimization include database configuration, caching, load balancing, and web server configuration. Specific techniques recommended are using RelStorage with PostgreSQL instead of ZEO, blob storage, memcached, microcaching, and configuring Nginx for load balancing and direct blob delivery. The goal is to speed up the entire request-response cycle in Plone.