2. Below is a sequence alignment of the FUS-RRM domains from different species. Identical residues are colored in red and highly conserved residues are in green. The RNA-binding domains are called RNP1 and RNP2 (red boxes) and the consensus sequence is at the bottom. a. Provide the amino acid number of one amino acid that - if mutated - you would predict would disrupt RNA binding: b. Provide the amino acid number of one amino acid that - if mutated - you would predict would not disrupt RNA binding:
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2- Below is a sequence alignment of the FUS-RRM domains from different.docx
1. 2. Below is a sequence alignment of the FUS-RRM domains from different species. Identical
residues are colored in red and highly conserved residues are in green. The RNA-binding
domains are called RNP1 and RNP2 (red boxes) and the consensus sequence is at the bottom. a.
Provide the amino acid number of one amino acid that - if mutated - you would predict would
disrupt RNA binding: b. Provide the amino acid number of one amino acid that - if mutated - you
would predict would not disrupt RNA binding:
