Civica will manufacture and distribute biosimilar insulins at an affordable price to help the millions of Americans who struggle to afford life-saving insulin medications. They plan to produce glargine, lispro and aspart insulin and sell them for no more than $30 per vial or $55 for a box of pen cartridges. This would represent up to a 90% discount compared to current market prices and ensure no one has to ration insulin due to cost. JDRF and other organizations are partnering with Civica to help reduce healthcare disparities and make insulin universally accessible.
On March 3, 2022, the nonprofit drug company Civica Rx announced its intention to introduce 3 insulin biosimilars at list prices which promise to be below copays and cost-sharing on insulin for many insured patients, as well as much less costly for uninsured patients.
This document provides background information on Scott Strumello and his assessment of why insulin prices are so high in the US. It discusses how Strumello investigated the issue and found that while drug companies share some blame, the primary culprits are health insurance companies. Insurance companies collect large rebates on insulin but fail to pass these savings to patients, instead using the money to offer premium discounts to employers. This forces many patients to pay the full list price of insulin out of pocket due to high deductible plans. While drug companies, pharmacy benefit managers, and legislators all play a role, Strumello argues that insurance companies deserve most of the blame for the rising out-of-pocket costs that patients face.
The document contains a transcript of an online discussion between Larry Soler, Vice President of Government Relations at the Juvenile Diabetes Research Foundation (JDRF), and several participants. Soler discusses JDRF's advocacy efforts and priorities, which include expanding stem cell research policies, increasing funding for juvenile diabetes research, and increasing the availability of pancreases for islet cell transplants. He explains how JDRF utilizes volunteers and grassroots organizing to effectively lobby Congress and influence policy on issues related to diabetes research.
Spinach and Artichoke Dip (Associated Press)sstrumello
This recipe provides instructions for making a spinach and artichoke dip appetizer. It calls for Greek yogurt, cream cheese, spinach, artichoke hearts, onions, herbs, and crushed whole-grain crackers. The ingredients are combined and baked for 10-15 minutes until hot. The dip serves 8 people and each serving contains 32 calories, 2g fat, 1g protein, and 3g carbohydrates.
The document outlines the agenda for Roche's 2011 Social Media Summit, including presentations and discussions on emerging diabetes social media trends, Roche products like insulin pumps and meters, and workshops on developing ideas for engaging the diabetes community online. The summit brings together Roche representatives and guests from diabetes organizations to share insights and strategize ways to enhance digital outreach efforts.
Civica will manufacture and distribute biosimilar insulins at an affordable price to help the millions of Americans who struggle to afford life-saving insulin medications. They plan to produce glargine, lispro and aspart insulin and sell them for no more than $30 per vial or $55 for a box of pen cartridges. This would represent up to a 90% discount compared to current market prices and ensure no one has to ration insulin due to cost. JDRF and other organizations are partnering with Civica to help reduce healthcare disparities and make insulin universally accessible.
On March 3, 2022, the nonprofit drug company Civica Rx announced its intention to introduce 3 insulin biosimilars at list prices which promise to be below copays and cost-sharing on insulin for many insured patients, as well as much less costly for uninsured patients.
This document provides background information on Scott Strumello and his assessment of why insulin prices are so high in the US. It discusses how Strumello investigated the issue and found that while drug companies share some blame, the primary culprits are health insurance companies. Insurance companies collect large rebates on insulin but fail to pass these savings to patients, instead using the money to offer premium discounts to employers. This forces many patients to pay the full list price of insulin out of pocket due to high deductible plans. While drug companies, pharmacy benefit managers, and legislators all play a role, Strumello argues that insurance companies deserve most of the blame for the rising out-of-pocket costs that patients face.
The document contains a transcript of an online discussion between Larry Soler, Vice President of Government Relations at the Juvenile Diabetes Research Foundation (JDRF), and several participants. Soler discusses JDRF's advocacy efforts and priorities, which include expanding stem cell research policies, increasing funding for juvenile diabetes research, and increasing the availability of pancreases for islet cell transplants. He explains how JDRF utilizes volunteers and grassroots organizing to effectively lobby Congress and influence policy on issues related to diabetes research.
Spinach and Artichoke Dip (Associated Press)sstrumello
This recipe provides instructions for making a spinach and artichoke dip appetizer. It calls for Greek yogurt, cream cheese, spinach, artichoke hearts, onions, herbs, and crushed whole-grain crackers. The ingredients are combined and baked for 10-15 minutes until hot. The dip serves 8 people and each serving contains 32 calories, 2g fat, 1g protein, and 3g carbohydrates.
The document outlines the agenda for Roche's 2011 Social Media Summit, including presentations and discussions on emerging diabetes social media trends, Roche products like insulin pumps and meters, and workshops on developing ideas for engaging the diabetes community online. The summit brings together Roche representatives and guests from diabetes organizations to share insights and strategize ways to enhance digital outreach efforts.
IDF Presentation to 2011 Roche Social Media Summitsstrumello
The International Diabetes Federation (IDF) is a global organization focused on diabetes care, prevention, and treatment. It has over 220 member associations in over 160 countries. The IDF aims to stem the growing global diabetes epidemic by advocating for policies and programs, raising awareness through events like World Diabetes Day, publishing research on diabetes prevalence and costs, and convening the global diabetes community. In the lead up to the 2011 UN Summit on non-communicable diseases, the IDF is lobbying governments to commit to national diabetes plans and increased resources to fight diabetes worldwide.
This document discusses how new diabetes technologies promise easier management but many people still struggle to maintain control or avoid burnout. While technology helps, people need breaks from the constant demands of diabetes care. The document contrasts unsafe breaks like ignoring treatment with safe breaks like occasional relaxed monitoring that don't compromise long-term health but provide needed relief. It encourages planning occasional breaks to sustain motivation and enjoying life with diabetes.
Biodel, Inc. Investor Presentation January 14, 2010sstrumello
This document summarizes a presentation given at the 28th Annual Healthcare Conference in San Francisco on January 14, 2010. The presentation was given by Biodel Inc., a company focused on developing enhanced insulin therapies for diabetes. Biodel discussed their lead product candidate VIAject, an ultra rapid-acting prandial insulin, which completed two successful Phase 3 trials and is awaiting FDA approval. The presentation provided an overview of Biodel's pipeline of diabetes programs, the insulin market opportunity, and preclinical and clinical data demonstrating VIAject's superior pharmacokinetic and pharmacodynamic profile compared to existing rapid-acting insulins.
Lola, a 2-year-old Yorkshire terrier, won first place in the "Smartest Pet in Queens" contest. She knows tricks like sit, paw down, and up, and likes to pretend fly. Princess, a mixed breed dog, came in second place. She can hold a ball in her mouth with her paws and prays without a ball. Phyllis, a half Siamese cat, took third place. She alerts her owner Scott of his juvenile diabetes episodes and ensures he is okay at night.
One of the latest success stories in diabetes research has been the development of anti-CD3 monoclonal antibodies to slow the progression of type 1 diabetes, which has been in development for over a decade. Two biotechnology companies, MacroGenics and Tolerx, are currently conducting phase III clinical trials testing different anti-CD3 drugs, with the goal of preserving insulin-producing beta cell function and reducing insulin needs. If successful, the results of these trials could provide evidence for FDA approval of anti-CD3 therapy as a treatment for newly diagnosed type 1 diabetes patients.
Most commercial insulin assays fail to detect recombinant insulin analoguessstrumello
Most commercial insulin assays are unable to accurately detect recombinant insulin analogues. A study published in 2006 found that many insulin tests on the market fail to measure modern insulin formulations that are genetically engineered versions of human insulin. This can lead to incorrect results when monitoring insulin levels in patients taking analogues.
Statement of Inger Mollerup, VP Novo Nordisk A/S for Congressional Hearings o...sstrumello
Inger Mollerup, Vice President of Novo Nordisk A/S, testified before the Government Oversight and Reform Committee about establishing a pathway for approval of follow-on biologics. She argued that any pathway must require clinical trials to demonstrate safety because even minor differences in biologics can have major health consequences, as shown through Novo Nordisk's experience. She also stated that traceability and unique names are important for pharmacovigilance, and that interchangeability is not supported by current science given potential immunogenicity differences between products.
Stanford University Case Study: Novo Nordisksstrumello
Novo Nordisk was historically the second largest producer of insulin in the world in 1981, supplying 25% of global demand. While it dominated the European market, it held less than 5% share in the large and lucrative US market, which was dominated by Eli Lilly at 83% share. By 1995, the insulin industry had consolidated significantly due to changes in technology, regulation, and competition. Novo broadened its product portfolio and global presence but continued to trail Eli Lilly in the important US market. Managing this competitive challenge would be a focus for Novo Nordisk's leadership going forward.
Could Generic Insulin Soon Hit the U.S. Market?sstrumello
Diabetes blogger Scott Strumello (sstrumello.blogspot.com) investigates whether follow-on (generic) insulin formulation will soon emerge in accordance with U.S. patent law.
Publish Date: January 1, 2007
Different Potencies of Biosynthetic Human and Purified Porcine Insulinsstrumello
The document summarizes research comparing the biological activity of purified porcine insulin and Biosynthetic Human Insulin (BHI) using the glucose clamp technique. The study found that:
1) BHI required significantly more glucose infusion than purified porcine insulin to maintain euglycemia, indicating BHI had higher biological activity.
2) Purified porcine insulin, but not BHI, induced significant increases in serum growth hormone and Cortisol concentrations.
3) There were no significant differences in serum insulin, glucose, or C-peptide levels between the two insulins.
Mental Health and well-being Presentation. Exploring innovative approaches and strategies for enhancing mental well-being. Discover cutting-edge research, effective strategies, and practical methods for fostering mental well-being.
The Importance of Black Women Understanding the Chemicals in Their Personal C...bkling
Certain chemicals, such as phthalates and parabens, can disrupt the body's hormones and have significant effects on health. According to data, hormone-related health issues such as uterine fibroids, infertility, early puberty and more aggressive forms of breast and endometrial cancers disproportionately affect Black women. Our guest speaker, Jasmine A. McDonald, PhD, an Assistant Professor in the Department of Epidemiology at Columbia University in New York City, discusses the scientific reasons why Black women should pay attention to specific chemicals in their personal care products, like hair care, and ways to minimize their exposure.
English Drug and Alcohol Commissioners June 2024.pptxMatSouthwell1
Presentation made by Mat Southwell to the Harm Reduction Working Group of the English Drug and Alcohol Commissioners. Discuss stimulants, OAMT, NSP coverage and community-led approach to DCRs. Focussing on active drug user perspectives and interests
CHAPTER 1 SEMESTER V COMMUNICATION TECHNIQUES FOR CHILDREN.pdfSachin Sharma
Here are some key objectives of communication with children:
Build Trust and Security:
Establish a safe and supportive environment where children feel comfortable expressing themselves.
Encourage Expression:
Enable children to articulate their thoughts, feelings, and experiences.
Promote Emotional Understanding:
Help children identify and understand their own emotions and the emotions of others.
Enhance Listening Skills:
Develop children’s ability to listen attentively and respond appropriately.
Foster Positive Relationships:
Strengthen the bond between children and caregivers, peers, and other adults.
Support Learning and Development:
Aid cognitive and language development through engaging and meaningful conversations.
Teach Social Skills:
Encourage polite, respectful, and empathetic interactions with others.
Resolve Conflicts:
Provide tools and guidance for children to handle disagreements constructively.
Encourage Independence:
Support children in making decisions and solving problems on their own.
Provide Reassurance and Comfort:
Offer comfort and understanding during times of distress or uncertainty.
Reinforce Positive Behavior:
Acknowledge and encourage positive actions and behaviors.
Guide and Educate:
Offer clear instructions and explanations to help children understand expectations and learn new concepts.
By focusing on these objectives, communication with children can be both effective and nurturing, supporting their overall growth and well-being.
IDF Presentation to 2011 Roche Social Media Summitsstrumello
The International Diabetes Federation (IDF) is a global organization focused on diabetes care, prevention, and treatment. It has over 220 member associations in over 160 countries. The IDF aims to stem the growing global diabetes epidemic by advocating for policies and programs, raising awareness through events like World Diabetes Day, publishing research on diabetes prevalence and costs, and convening the global diabetes community. In the lead up to the 2011 UN Summit on non-communicable diseases, the IDF is lobbying governments to commit to national diabetes plans and increased resources to fight diabetes worldwide.
This document discusses how new diabetes technologies promise easier management but many people still struggle to maintain control or avoid burnout. While technology helps, people need breaks from the constant demands of diabetes care. The document contrasts unsafe breaks like ignoring treatment with safe breaks like occasional relaxed monitoring that don't compromise long-term health but provide needed relief. It encourages planning occasional breaks to sustain motivation and enjoying life with diabetes.
Biodel, Inc. Investor Presentation January 14, 2010sstrumello
This document summarizes a presentation given at the 28th Annual Healthcare Conference in San Francisco on January 14, 2010. The presentation was given by Biodel Inc., a company focused on developing enhanced insulin therapies for diabetes. Biodel discussed their lead product candidate VIAject, an ultra rapid-acting prandial insulin, which completed two successful Phase 3 trials and is awaiting FDA approval. The presentation provided an overview of Biodel's pipeline of diabetes programs, the insulin market opportunity, and preclinical and clinical data demonstrating VIAject's superior pharmacokinetic and pharmacodynamic profile compared to existing rapid-acting insulins.
Lola, a 2-year-old Yorkshire terrier, won first place in the "Smartest Pet in Queens" contest. She knows tricks like sit, paw down, and up, and likes to pretend fly. Princess, a mixed breed dog, came in second place. She can hold a ball in her mouth with her paws and prays without a ball. Phyllis, a half Siamese cat, took third place. She alerts her owner Scott of his juvenile diabetes episodes and ensures he is okay at night.
One of the latest success stories in diabetes research has been the development of anti-CD3 monoclonal antibodies to slow the progression of type 1 diabetes, which has been in development for over a decade. Two biotechnology companies, MacroGenics and Tolerx, are currently conducting phase III clinical trials testing different anti-CD3 drugs, with the goal of preserving insulin-producing beta cell function and reducing insulin needs. If successful, the results of these trials could provide evidence for FDA approval of anti-CD3 therapy as a treatment for newly diagnosed type 1 diabetes patients.
Most commercial insulin assays fail to detect recombinant insulin analoguessstrumello
Most commercial insulin assays are unable to accurately detect recombinant insulin analogues. A study published in 2006 found that many insulin tests on the market fail to measure modern insulin formulations that are genetically engineered versions of human insulin. This can lead to incorrect results when monitoring insulin levels in patients taking analogues.
Statement of Inger Mollerup, VP Novo Nordisk A/S for Congressional Hearings o...sstrumello
Inger Mollerup, Vice President of Novo Nordisk A/S, testified before the Government Oversight and Reform Committee about establishing a pathway for approval of follow-on biologics. She argued that any pathway must require clinical trials to demonstrate safety because even minor differences in biologics can have major health consequences, as shown through Novo Nordisk's experience. She also stated that traceability and unique names are important for pharmacovigilance, and that interchangeability is not supported by current science given potential immunogenicity differences between products.
Stanford University Case Study: Novo Nordisksstrumello
Novo Nordisk was historically the second largest producer of insulin in the world in 1981, supplying 25% of global demand. While it dominated the European market, it held less than 5% share in the large and lucrative US market, which was dominated by Eli Lilly at 83% share. By 1995, the insulin industry had consolidated significantly due to changes in technology, regulation, and competition. Novo broadened its product portfolio and global presence but continued to trail Eli Lilly in the important US market. Managing this competitive challenge would be a focus for Novo Nordisk's leadership going forward.
Could Generic Insulin Soon Hit the U.S. Market?sstrumello
Diabetes blogger Scott Strumello (sstrumello.blogspot.com) investigates whether follow-on (generic) insulin formulation will soon emerge in accordance with U.S. patent law.
Publish Date: January 1, 2007
Different Potencies of Biosynthetic Human and Purified Porcine Insulinsstrumello
The document summarizes research comparing the biological activity of purified porcine insulin and Biosynthetic Human Insulin (BHI) using the glucose clamp technique. The study found that:
1) BHI required significantly more glucose infusion than purified porcine insulin to maintain euglycemia, indicating BHI had higher biological activity.
2) Purified porcine insulin, but not BHI, induced significant increases in serum growth hormone and Cortisol concentrations.
3) There were no significant differences in serum insulin, glucose, or C-peptide levels between the two insulins.
Mental Health and well-being Presentation. Exploring innovative approaches and strategies for enhancing mental well-being. Discover cutting-edge research, effective strategies, and practical methods for fostering mental well-being.
The Importance of Black Women Understanding the Chemicals in Their Personal C...bkling
Certain chemicals, such as phthalates and parabens, can disrupt the body's hormones and have significant effects on health. According to data, hormone-related health issues such as uterine fibroids, infertility, early puberty and more aggressive forms of breast and endometrial cancers disproportionately affect Black women. Our guest speaker, Jasmine A. McDonald, PhD, an Assistant Professor in the Department of Epidemiology at Columbia University in New York City, discusses the scientific reasons why Black women should pay attention to specific chemicals in their personal care products, like hair care, and ways to minimize their exposure.
English Drug and Alcohol Commissioners June 2024.pptxMatSouthwell1
Presentation made by Mat Southwell to the Harm Reduction Working Group of the English Drug and Alcohol Commissioners. Discuss stimulants, OAMT, NSP coverage and community-led approach to DCRs. Focussing on active drug user perspectives and interests
CHAPTER 1 SEMESTER V COMMUNICATION TECHNIQUES FOR CHILDREN.pdfSachin Sharma
Here are some key objectives of communication with children:
Build Trust and Security:
Establish a safe and supportive environment where children feel comfortable expressing themselves.
Encourage Expression:
Enable children to articulate their thoughts, feelings, and experiences.
Promote Emotional Understanding:
Help children identify and understand their own emotions and the emotions of others.
Enhance Listening Skills:
Develop children’s ability to listen attentively and respond appropriately.
Foster Positive Relationships:
Strengthen the bond between children and caregivers, peers, and other adults.
Support Learning and Development:
Aid cognitive and language development through engaging and meaningful conversations.
Teach Social Skills:
Encourage polite, respectful, and empathetic interactions with others.
Resolve Conflicts:
Provide tools and guidance for children to handle disagreements constructively.
Encourage Independence:
Support children in making decisions and solving problems on their own.
Provide Reassurance and Comfort:
Offer comfort and understanding during times of distress or uncertainty.
Reinforce Positive Behavior:
Acknowledge and encourage positive actions and behaviors.
Guide and Educate:
Offer clear instructions and explanations to help children understand expectations and learn new concepts.
By focusing on these objectives, communication with children can be both effective and nurturing, supporting their overall growth and well-being.
Digital Health in India_Health Informatics Trained Manpower _DrDevTaneja_15.0...DrDevTaneja1
Digital India will need a big trained army of Health Informatics educated & trained manpower in India.
Presently, generalist IT manpower does most of the work in the healthcare industry in India. Academic Health Informatics education is not readily available at school & health university level or IT education institutions in India.
We look into the evolution of health informatics and its applications in the healthcare industry.
HIMMS TIGER resources are available to assist Health Informatics education.
Indian Health universities, IT Education institutions, and the healthcare industry must proactively collaborate to start health informatics courses on a big scale. An advocacy push from various stakeholders is also needed for this goal.
Health informatics has huge employment potential and provides a big business opportunity for the healthcare industry. A big pool of trained health informatics manpower can lead to product & service innovations on a global scale in India.
NURSING MANAGEMENT OF PATIENT WITH EMPHYSEMA .PPTblessyjannu21
Prepared by Prof. BLESSY THOMAS, VICE PRINCIPAL, FNCON, SPN.
Emphysema is a disease condition of respiratory system.
Emphysema is an abnormal permanent enlargement of the air spaces distal to terminal bronchioles, accompanied by destruction of their walls and without obvious fibrosis.
Emphysema of lung is defined as hyper inflation of the lung ais spaces due to obstruction of non respiratory bronchioles as due to loss of elasticity of alveoli.
It is a type of chronic obstructive
pulmonary disease.
It is a progressive disease of lungs.
The facial nerve, also known as cranial nerve VII, is one of the 12 cranial nerves originating from the brain. It's a mixed nerve, meaning it contains both sensory and motor fibres, and it plays a crucial role in controlling various facial muscles, as well as conveying sensory information from the taste buds on the anterior two-thirds of the tongue.
Get Covid Testing at Fit to Fly PCR TestNX Healthcare
A Fit-to-Fly PCR Test is a crucial service for travelers needing to meet the entry requirements of various countries or airlines. This test involves a polymerase chain reaction (PCR) test for COVID-19, which is considered the gold standard for detecting active infections. At our travel clinic in Leeds, we offer fast and reliable Fit to Fly PCR testing, providing you with an official certificate verifying your negative COVID-19 status. Our process is designed for convenience and accuracy, with quick turnaround times to ensure you receive your results and certificate in time for your departure. Trust our professional and experienced medical team to help you travel safely and compliantly, giving you peace of mind for your journey.www.nxhealthcare.co.uk
End-tidal carbon dioxide (ETCO2) is the level of carbon dioxide that is released at the end of an exhaled breath. ETCO2 levels reflect the adequacy with which carbon dioxide (CO2) is carried in the blood back to the lungs and exhaled.
Non-invasive methods for ETCO2 measurement include capnometry and capnography. Capnometry provides a numerical value for ETCO2. In contrast, capnography delivers a more comprehensive measurement that is displayed in both graphical (waveform) and numerical form.
Sidestream devices can monitor both intubated and non-intubated patients, while mainstream devices are most often limited to intubated patients.