Civica will manufacture and distribute biosimilar insulins at an affordable price to help the millions of Americans who struggle to afford life-saving insulin medications. They plan to produce glargine, lispro and aspart insulin and sell them for no more than $30 per vial or $55 for a box of pen cartridges. This would represent up to a 90% discount compared to current market prices and ensure no one has to ration insulin due to cost. JDRF and other organizations are partnering with Civica to help reduce healthcare disparities and make insulin universally accessible.
On March 3, 2022, the nonprofit drug company Civica Rx announced its intention to introduce 3 insulin biosimilars at list prices which promise to be below copays and cost-sharing on insulin for many insured patients, as well as much less costly for uninsured patients.
This document provides background information on Scott Strumello and his assessment of why insulin prices are so high in the US. It discusses how Strumello investigated the issue and found that while drug companies share some blame, the primary culprits are health insurance companies. Insurance companies collect large rebates on insulin but fail to pass these savings to patients, instead using the money to offer premium discounts to employers. This forces many patients to pay the full list price of insulin out of pocket due to high deductible plans. While drug companies, pharmacy benefit managers, and legislators all play a role, Strumello argues that insurance companies deserve most of the blame for the rising out-of-pocket costs that patients face.
The document contains a transcript of an online discussion between Larry Soler, Vice President of Government Relations at the Juvenile Diabetes Research Foundation (JDRF), and several participants. Soler discusses JDRF's advocacy efforts and priorities, which include expanding stem cell research policies, increasing funding for juvenile diabetes research, and increasing the availability of pancreases for islet cell transplants. He explains how JDRF utilizes volunteers and grassroots organizing to effectively lobby Congress and influence policy on issues related to diabetes research.
Spinach and Artichoke Dip (Associated Press)sstrumello
This recipe provides instructions for making a spinach and artichoke dip appetizer. It calls for Greek yogurt, cream cheese, spinach, artichoke hearts, onions, herbs, and crushed whole-grain crackers. The ingredients are combined and baked for 10-15 minutes until hot. The dip serves 8 people and each serving contains 32 calories, 2g fat, 1g protein, and 3g carbohydrates.
The document outlines the agenda for Roche's 2011 Social Media Summit, including presentations and discussions on emerging diabetes social media trends, Roche products like insulin pumps and meters, and workshops on developing ideas for engaging the diabetes community online. The summit brings together Roche representatives and guests from diabetes organizations to share insights and strategize ways to enhance digital outreach efforts.
Civica will manufacture and distribute biosimilar insulins at an affordable price to help the millions of Americans who struggle to afford life-saving insulin medications. They plan to produce glargine, lispro and aspart insulin and sell them for no more than $30 per vial or $55 for a box of pen cartridges. This would represent up to a 90% discount compared to current market prices and ensure no one has to ration insulin due to cost. JDRF and other organizations are partnering with Civica to help reduce healthcare disparities and make insulin universally accessible.
On March 3, 2022, the nonprofit drug company Civica Rx announced its intention to introduce 3 insulin biosimilars at list prices which promise to be below copays and cost-sharing on insulin for many insured patients, as well as much less costly for uninsured patients.
This document provides background information on Scott Strumello and his assessment of why insulin prices are so high in the US. It discusses how Strumello investigated the issue and found that while drug companies share some blame, the primary culprits are health insurance companies. Insurance companies collect large rebates on insulin but fail to pass these savings to patients, instead using the money to offer premium discounts to employers. This forces many patients to pay the full list price of insulin out of pocket due to high deductible plans. While drug companies, pharmacy benefit managers, and legislators all play a role, Strumello argues that insurance companies deserve most of the blame for the rising out-of-pocket costs that patients face.
The document contains a transcript of an online discussion between Larry Soler, Vice President of Government Relations at the Juvenile Diabetes Research Foundation (JDRF), and several participants. Soler discusses JDRF's advocacy efforts and priorities, which include expanding stem cell research policies, increasing funding for juvenile diabetes research, and increasing the availability of pancreases for islet cell transplants. He explains how JDRF utilizes volunteers and grassroots organizing to effectively lobby Congress and influence policy on issues related to diabetes research.
Spinach and Artichoke Dip (Associated Press)sstrumello
This recipe provides instructions for making a spinach and artichoke dip appetizer. It calls for Greek yogurt, cream cheese, spinach, artichoke hearts, onions, herbs, and crushed whole-grain crackers. The ingredients are combined and baked for 10-15 minutes until hot. The dip serves 8 people and each serving contains 32 calories, 2g fat, 1g protein, and 3g carbohydrates.
The document outlines the agenda for Roche's 2011 Social Media Summit, including presentations and discussions on emerging diabetes social media trends, Roche products like insulin pumps and meters, and workshops on developing ideas for engaging the diabetes community online. The summit brings together Roche representatives and guests from diabetes organizations to share insights and strategize ways to enhance digital outreach efforts.
IDF Presentation to 2011 Roche Social Media Summitsstrumello
The International Diabetes Federation (IDF) is a global organization focused on diabetes care, prevention, and treatment. It has over 220 member associations in over 160 countries. The IDF aims to stem the growing global diabetes epidemic by advocating for policies and programs, raising awareness through events like World Diabetes Day, publishing research on diabetes prevalence and costs, and convening the global diabetes community. In the lead up to the 2011 UN Summit on non-communicable diseases, the IDF is lobbying governments to commit to national diabetes plans and increased resources to fight diabetes worldwide.
This document discusses how new diabetes technologies promise easier management but many people still struggle to maintain control or avoid burnout. While technology helps, people need breaks from the constant demands of diabetes care. The document contrasts unsafe breaks like ignoring treatment with safe breaks like occasional relaxed monitoring that don't compromise long-term health but provide needed relief. It encourages planning occasional breaks to sustain motivation and enjoying life with diabetes.
Biodel, Inc. Investor Presentation January 14, 2010sstrumello
This document summarizes a presentation given at the 28th Annual Healthcare Conference in San Francisco on January 14, 2010. The presentation was given by Biodel Inc., a company focused on developing enhanced insulin therapies for diabetes. Biodel discussed their lead product candidate VIAject, an ultra rapid-acting prandial insulin, which completed two successful Phase 3 trials and is awaiting FDA approval. The presentation provided an overview of Biodel's pipeline of diabetes programs, the insulin market opportunity, and preclinical and clinical data demonstrating VIAject's superior pharmacokinetic and pharmacodynamic profile compared to existing rapid-acting insulins.
Lola, a 2-year-old Yorkshire terrier, won first place in the "Smartest Pet in Queens" contest. She knows tricks like sit, paw down, and up, and likes to pretend fly. Princess, a mixed breed dog, came in second place. She can hold a ball in her mouth with her paws and prays without a ball. Phyllis, a half Siamese cat, took third place. She alerts her owner Scott of his juvenile diabetes episodes and ensures he is okay at night.
One of the latest success stories in diabetes research has been the development of anti-CD3 monoclonal antibodies to slow the progression of type 1 diabetes, which has been in development for over a decade. Two biotechnology companies, MacroGenics and Tolerx, are currently conducting phase III clinical trials testing different anti-CD3 drugs, with the goal of preserving insulin-producing beta cell function and reducing insulin needs. If successful, the results of these trials could provide evidence for FDA approval of anti-CD3 therapy as a treatment for newly diagnosed type 1 diabetes patients.
Most commercial insulin assays fail to detect recombinant insulin analoguessstrumello
Most commercial insulin assays are unable to accurately detect recombinant insulin analogues. A study published in 2006 found that many insulin tests on the market fail to measure modern insulin formulations that are genetically engineered versions of human insulin. This can lead to incorrect results when monitoring insulin levels in patients taking analogues.
Statement of Inger Mollerup, VP Novo Nordisk A/S for Congressional Hearings o...sstrumello
Inger Mollerup, Vice President of Novo Nordisk A/S, testified before the Government Oversight and Reform Committee about establishing a pathway for approval of follow-on biologics. She argued that any pathway must require clinical trials to demonstrate safety because even minor differences in biologics can have major health consequences, as shown through Novo Nordisk's experience. She also stated that traceability and unique names are important for pharmacovigilance, and that interchangeability is not supported by current science given potential immunogenicity differences between products.
Stanford University Case Study: Novo Nordisksstrumello
Novo Nordisk was historically the second largest producer of insulin in the world in 1981, supplying 25% of global demand. While it dominated the European market, it held less than 5% share in the large and lucrative US market, which was dominated by Eli Lilly at 83% share. By 1995, the insulin industry had consolidated significantly due to changes in technology, regulation, and competition. Novo broadened its product portfolio and global presence but continued to trail Eli Lilly in the important US market. Managing this competitive challenge would be a focus for Novo Nordisk's leadership going forward.
Could Generic Insulin Soon Hit the U.S. Market?sstrumello
Diabetes blogger Scott Strumello (sstrumello.blogspot.com) investigates whether follow-on (generic) insulin formulation will soon emerge in accordance with U.S. patent law.
Publish Date: January 1, 2007
Different Potencies of Biosynthetic Human and Purified Porcine Insulinsstrumello
The document summarizes research comparing the biological activity of purified porcine insulin and Biosynthetic Human Insulin (BHI) using the glucose clamp technique. The study found that:
1) BHI required significantly more glucose infusion than purified porcine insulin to maintain euglycemia, indicating BHI had higher biological activity.
2) Purified porcine insulin, but not BHI, induced significant increases in serum growth hormone and Cortisol concentrations.
3) There were no significant differences in serum insulin, glucose, or C-peptide levels between the two insulins.
Michigan HealthTech Market Map 2024. Includes 7 categories: Policy Makers, Academic Innovation Centers, Digital Health Providers, Healthcare Providers, Payers / Insurance, Device Companies, Life Science Companies, Innovation Accelerators. Developed by the Michigan-Israel Business Accelerator
At Apollo Hospital, Lucknow, U.P., we provide specialized care for children experiencing dehydration and other symptoms. We also offer NICU & PICU Ambulance Facility Services. Consult our expert today for the best pediatric emergency care.
For More Details:
Map: https://cutt.ly/BwCeflYo
Name: Apollo Hospital
Address: Singar Nagar, LDA Colony, Lucknow, Uttar Pradesh 226012
Phone: 08429021957
Opening Hours: 24X7
Can Allopathy and Homeopathy Be Used Together in India.pdfDharma Homoeopathy
This article explores the potential for combining allopathy and homeopathy in India, examining the benefits, challenges, and the emerging field of integrative medicine.
LGBTQ+ Adults: Unique Opportunities and Inclusive Approaches to CareVITASAuthor
This webinar helps clinicians understand the unique healthcare needs of the LGBTQ+ community, primarily in relation to end-of-life care. Topics include social and cultural background and challenges, healthcare disparities, advanced care planning, and strategies for reaching the community and improving quality of care.
The best massage spa Ajman is Chandrima Spa Ajman, which was founded in 2023 and is exclusively for men 24 hours a day. As of right now, our parent firm has been providing massage services to over 50,000+ clients in Ajman for the past 10 years. It has about 8+ branches. This demonstrates that Chandrima Spa Ajman is among the most reasonably priced spas in Ajman and the ideal place to unwind and rejuvenate. We provide a wide range of Spa massage treatments, including Indian, Pakistani, Kerala, Malayali, and body-to-body massages. Numerous massage techniques are available, including deep tissue, Swedish, Thai, Russian, and hot stone massages. Our massage therapists produce genuinely unique treatments that generate a revitalized sense of inner serenely by fusing modern techniques, the cleanest natural substances, and traditional holistic therapists.
IDF Presentation to 2011 Roche Social Media Summitsstrumello
The International Diabetes Federation (IDF) is a global organization focused on diabetes care, prevention, and treatment. It has over 220 member associations in over 160 countries. The IDF aims to stem the growing global diabetes epidemic by advocating for policies and programs, raising awareness through events like World Diabetes Day, publishing research on diabetes prevalence and costs, and convening the global diabetes community. In the lead up to the 2011 UN Summit on non-communicable diseases, the IDF is lobbying governments to commit to national diabetes plans and increased resources to fight diabetes worldwide.
This document discusses how new diabetes technologies promise easier management but many people still struggle to maintain control or avoid burnout. While technology helps, people need breaks from the constant demands of diabetes care. The document contrasts unsafe breaks like ignoring treatment with safe breaks like occasional relaxed monitoring that don't compromise long-term health but provide needed relief. It encourages planning occasional breaks to sustain motivation and enjoying life with diabetes.
Biodel, Inc. Investor Presentation January 14, 2010sstrumello
This document summarizes a presentation given at the 28th Annual Healthcare Conference in San Francisco on January 14, 2010. The presentation was given by Biodel Inc., a company focused on developing enhanced insulin therapies for diabetes. Biodel discussed their lead product candidate VIAject, an ultra rapid-acting prandial insulin, which completed two successful Phase 3 trials and is awaiting FDA approval. The presentation provided an overview of Biodel's pipeline of diabetes programs, the insulin market opportunity, and preclinical and clinical data demonstrating VIAject's superior pharmacokinetic and pharmacodynamic profile compared to existing rapid-acting insulins.
Lola, a 2-year-old Yorkshire terrier, won first place in the "Smartest Pet in Queens" contest. She knows tricks like sit, paw down, and up, and likes to pretend fly. Princess, a mixed breed dog, came in second place. She can hold a ball in her mouth with her paws and prays without a ball. Phyllis, a half Siamese cat, took third place. She alerts her owner Scott of his juvenile diabetes episodes and ensures he is okay at night.
One of the latest success stories in diabetes research has been the development of anti-CD3 monoclonal antibodies to slow the progression of type 1 diabetes, which has been in development for over a decade. Two biotechnology companies, MacroGenics and Tolerx, are currently conducting phase III clinical trials testing different anti-CD3 drugs, with the goal of preserving insulin-producing beta cell function and reducing insulin needs. If successful, the results of these trials could provide evidence for FDA approval of anti-CD3 therapy as a treatment for newly diagnosed type 1 diabetes patients.
Most commercial insulin assays fail to detect recombinant insulin analoguessstrumello
Most commercial insulin assays are unable to accurately detect recombinant insulin analogues. A study published in 2006 found that many insulin tests on the market fail to measure modern insulin formulations that are genetically engineered versions of human insulin. This can lead to incorrect results when monitoring insulin levels in patients taking analogues.
Statement of Inger Mollerup, VP Novo Nordisk A/S for Congressional Hearings o...sstrumello
Inger Mollerup, Vice President of Novo Nordisk A/S, testified before the Government Oversight and Reform Committee about establishing a pathway for approval of follow-on biologics. She argued that any pathway must require clinical trials to demonstrate safety because even minor differences in biologics can have major health consequences, as shown through Novo Nordisk's experience. She also stated that traceability and unique names are important for pharmacovigilance, and that interchangeability is not supported by current science given potential immunogenicity differences between products.
Stanford University Case Study: Novo Nordisksstrumello
Novo Nordisk was historically the second largest producer of insulin in the world in 1981, supplying 25% of global demand. While it dominated the European market, it held less than 5% share in the large and lucrative US market, which was dominated by Eli Lilly at 83% share. By 1995, the insulin industry had consolidated significantly due to changes in technology, regulation, and competition. Novo broadened its product portfolio and global presence but continued to trail Eli Lilly in the important US market. Managing this competitive challenge would be a focus for Novo Nordisk's leadership going forward.
Could Generic Insulin Soon Hit the U.S. Market?sstrumello
Diabetes blogger Scott Strumello (sstrumello.blogspot.com) investigates whether follow-on (generic) insulin formulation will soon emerge in accordance with U.S. patent law.
Publish Date: January 1, 2007
Different Potencies of Biosynthetic Human and Purified Porcine Insulinsstrumello
The document summarizes research comparing the biological activity of purified porcine insulin and Biosynthetic Human Insulin (BHI) using the glucose clamp technique. The study found that:
1) BHI required significantly more glucose infusion than purified porcine insulin to maintain euglycemia, indicating BHI had higher biological activity.
2) Purified porcine insulin, but not BHI, induced significant increases in serum growth hormone and Cortisol concentrations.
3) There were no significant differences in serum insulin, glucose, or C-peptide levels between the two insulins.
Michigan HealthTech Market Map 2024. Includes 7 categories: Policy Makers, Academic Innovation Centers, Digital Health Providers, Healthcare Providers, Payers / Insurance, Device Companies, Life Science Companies, Innovation Accelerators. Developed by the Michigan-Israel Business Accelerator
At Apollo Hospital, Lucknow, U.P., we provide specialized care for children experiencing dehydration and other symptoms. We also offer NICU & PICU Ambulance Facility Services. Consult our expert today for the best pediatric emergency care.
For More Details:
Map: https://cutt.ly/BwCeflYo
Name: Apollo Hospital
Address: Singar Nagar, LDA Colony, Lucknow, Uttar Pradesh 226012
Phone: 08429021957
Opening Hours: 24X7
Can Allopathy and Homeopathy Be Used Together in India.pdfDharma Homoeopathy
This article explores the potential for combining allopathy and homeopathy in India, examining the benefits, challenges, and the emerging field of integrative medicine.
LGBTQ+ Adults: Unique Opportunities and Inclusive Approaches to CareVITASAuthor
This webinar helps clinicians understand the unique healthcare needs of the LGBTQ+ community, primarily in relation to end-of-life care. Topics include social and cultural background and challenges, healthcare disparities, advanced care planning, and strategies for reaching the community and improving quality of care.
The best massage spa Ajman is Chandrima Spa Ajman, which was founded in 2023 and is exclusively for men 24 hours a day. As of right now, our parent firm has been providing massage services to over 50,000+ clients in Ajman for the past 10 years. It has about 8+ branches. This demonstrates that Chandrima Spa Ajman is among the most reasonably priced spas in Ajman and the ideal place to unwind and rejuvenate. We provide a wide range of Spa massage treatments, including Indian, Pakistani, Kerala, Malayali, and body-to-body massages. Numerous massage techniques are available, including deep tissue, Swedish, Thai, Russian, and hot stone massages. Our massage therapists produce genuinely unique treatments that generate a revitalized sense of inner serenely by fusing modern techniques, the cleanest natural substances, and traditional holistic therapists.
Can coffee help me lose weight? Yes, 25,422 users in the USA use it for that ...nirahealhty
The South Beach Coffee Java Diet is a variation of the popular South Beach Diet, which was developed by cardiologist Dr. Arthur Agatston. The original South Beach Diet focuses on consuming lean proteins, healthy fats, and low-glycemic index carbohydrates. The South Beach Coffee Java Diet adds the element of coffee, specifically caffeine, to enhance weight loss and improve energy levels.
Unlocking the Secrets to Safe Patient Handling.pdfLift Ability
Furthermore, the time constraints and workload in healthcare settings can make it challenging for caregivers to prioritise safe patient handling Australia practices, leading to shortcuts and increased risks.
Hypertension and it's role of physiotherapy in it.Vishal kr Thakur
This particular slides consist of- what is hypertension,what are it's causes and it's effect on body, risk factors, symptoms,complications, diagnosis and role of physiotherapy in it.
This slide is very helpful for physiotherapy students and also for other medical and healthcare students.
Here is summary of hypertension -
Hypertension, also known as high blood pressure, is a serious medical condition that occurs when blood pressure in the body's arteries is consistently too high. Blood pressure is the force of blood pushing against the walls of blood vessels as the heart pumps it. Hypertension can increase the risk of heart disease, brain disease, kidney disease, and premature death.
Joker Wigs has been a one-stop-shop for hair products for over 26 years. We provide high-quality hair wigs, hair extensions, hair toppers, hair patch, and more for both men and women.
Chandrima Spa Ajman is one of the leading Massage Center in Ajman, which is open 24 hours exclusively for men. Being one of the most affordable Spa in Ajman, we offer Body to Body massage, Kerala Massage, Malayali Massage, Indian Massage, Pakistani Massage Russian massage, Thai massage, Swedish massage, Hot Stone Massage, Deep Tissue Massage, and many more. Indulge in the ultimate massage experience and book your appointment today. We are confident that you will leave our Massage spa feeling refreshed, rejuvenated, and ready to take on the world.
Visit : https://massagespaajman.com/
Call : 052 987 1315
DECODING THE RISKS - ALCOHOL, TOBACCO & DRUGS.pdfDr Rachana Gujar
Introduction: Substance use education is crucial due to its prevalence and societal impact.
Alcohol Use: Immediate and long-term risks include impaired judgment, health issues, and social consequences.
Tobacco Use: Immediate effects include increased heart rate, while long-term risks encompass cancer and heart disease.
Drug Use: Risks vary depending on the drug type, including health and psychological implications.
Prevention Strategies: Education, healthy coping mechanisms, community support, and policies are vital in preventing substance use.
Harm Reduction Strategies: Safe use practices, medication-assisted treatment, and naloxone availability aim to reduce harm.
Seeking Help for Addiction: Recognizing signs, available treatments, support systems, and resources are essential for recovery.
Personal Stories: Real stories of recovery emphasize hope and resilience.
Interactive Q&A: Engage the audience and encourage discussion.
Conclusion: Recap key points and emphasize the importance of awareness, prevention, and seeking help.
Resources: Provide contact information and links for further support.
Exploring the Benefits of Binaural Hearing: Why Two Hearing Aids Are Better T...Ear Solutions (ESPL)
Binaural hearing using two hearing aids instead of one offers numerous advantages, including improved sound localization, enhanced sound quality, better speech understanding in noise, reduced listening effort, and greater overall satisfaction. By leveraging the brain’s natural ability to process sound from both ears, binaural hearing aids provide a more balanced, clear, and comfortable hearing experience. If you or a loved one is considering hearing aids, consult with a hearing care professional at Ear Solutions hearing aid clinic in Mumbai to explore the benefits of binaural hearing and determine the best solution for your hearing needs. Embracing binaural hearing can lead to a richer, more engaging auditory experience and significantly improve your quality of life.
The facial nerve, also known as cranial nerve VII, is one of the 12 cranial nerves originating from the brain. It's a mixed nerve, meaning it contains both sensory and motor fibres, and it plays a crucial role in controlling various facial muscles, as well as conveying sensory information from the taste buds on the anterior two-thirds of the tongue.