This document provides a reasoned decision by the United States Anti-Doping Agency (USADA) imposing a lifetime ban and disqualification of competitive results on cyclist Lance Armstrong dating back to 1998. The decision is based on sworn statements from 24 witnesses including 15 cyclists and members of Armstrong's teams, as well as banking records, emails, and laboratory analysis. The evidence demonstrates Armstrong's involvement in doping throughout his career in violation of anti-doping rules.