1) Several NFL players have played through significant injuries, including Portis playing with a broken fibula and Emmitt Smith rushing for 170 yards and 10 receptions after separating his shoulder. 2) In college, Byron Leftwich refused to leave a game for Akron despite breaking his tibia and helped lead a comeback. Clay Matthews had 14 sacks one season playing through a stress fracture in his shin. 3) Brett Favre played through many injuries maintaining his streak of 297 straight starts, including leading a comeback in the NFC Championship game with the Vikings while playing through a foot injury and hamstring issues.