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Botulinum toxin in cerebral palsy
1. Botulinum toxin in cerebral palsy
โข Available in powder form
โข Acts on motor end plates
โข Stop the release of acetylcholine
โข So, decreases the muscle activity of spastic
muscle .
โข This injection is more effective in younger
children .. Recommended age is 2-6 years
โข Recommended dose in one go is 300 IU
2. โข Given in hamstrings , rectus femoris ,
gastronemius , iliopsoas , tibialis posterior
โข Also given in pronator teres , flexor carpi
ulnaris and adductor pollicis
โข Posture and gait pattern improves within a
week.
โข Its not a permanent form of treatment
โข After 6 months to 1 year , effect started
weaning off.