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3 types
1. Exocrine glands
2. Endocrine glands
3. Hetrocrine glands
Hormone
How hormones work?
Positive feedback mechanism
Endocrine glands
• 1 Pineal gland
• 2 Pituitary gland
• 3 Thyroid gland
• 4 Thymus
• 5 Adrenal gland
• 6 Pancreas
• 7 Ovary (female)
• 8 Testis (male)
Hypophysis cerebri – Pituitary gland
• Master gland: Control other endocrine glands
Facts
• Pear shaped gland
• Measures 1 – 1.5cm in diameter
• 6mm height & 9mm breath
• Wt: 500 to 900 mg (pregnancy : 1g)
• Larger in women
• Attaches with hypothalamus by stalk – infundibulum and
both acts as a single unit
Location: Small depression of sphenoid
bone, known as sella turcica –
hypophyseal fossa
Anatomical relations:
• Anteriorly – Anterior inter cavernous sinus
• Posteriorly – posterior inter cavernous sinus and posterior
wall of the sella turcica
• Superiorly – fold of dura mater that covers the pituitary
gland, optic chiasm and hypothalamus
• Inferiorly – sphenoid sinus
• Laterally – cavernous sinuses.
PI = pituitary gland,
AICS, PICS = Anterior and
posterior intercavernous
sinuses,
SPH = sphenoid sinus.
Anterior Lobe - 3 parts:
• Pars Anterior / distalis – largest part, secretes
hormones under the control of the hypothalamus,
via neurotransmitters
• Pars tuberalis – upwards extension of pars anterior
• Pars intermedia – thin layer that separates the
pars anterior from the posterior lobe of pituitary.
Anterior lobe – Adeno hypophysis
(75%)
5 types of glandular tissue
1. Somatotrophs
2. Thyrotrophs
3. Gonadotrophs
4. Lactotrophs
5. Corticotrophs
Posterior pituitary – neurohypophysis
( 25% )
• It is an extension of hypothalamus
• Contains neural tissue
• It does not produce hormones, but the hormones
produced by the hypothalamus travel to the posterior
pituitary stored and released when needed
• Oxytocin and ADH.
Posterior Lobe / neurohypophysis:
.
• Neurons have their cell bodies in the supra optic para
ventricular nuclei of hypothalamus and their axon
forms a bundle known as hypothalamo hypophyseal
tract
• Posterior piyuitary hormones are produced in the
nerve cell bodies transported through theses axons
and stored in vesicles in axon terminals in the posterior
Pituitary.
• Release by exocytocis is trigerred by nerve impulse
from hypothalamus
Melanocyte Stimulating Hormone
• Secreted by the intermediate lobe of the pituitary
gland and function primarily on skin darkening by
stimulating the production and release of melanin
• Also produced by hypothalamus and skin cells.
• Protecting the skin from UV rays
Blood supply: Anterior Pituitary
• Superior hypophyseal artery first forms a capillary network
around the hypothalamus – blood from this network is then
transported the anterior pituitary that allows the communication
via the release of neurotransmitters into the bloodstream.
Posterior Pituitary
• Superior hypophyseal artery, infundibular artery and inferior
hypophyseal artery.
• Venous drainage - Anterior and posterior hypophyseal veins
endocrine system.pptx
endocrine system.pptx

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endocrine system.pptx

  • 1.
  • 2.
  • 3.
  • 4. 3 types 1. Exocrine glands 2. Endocrine glands 3. Hetrocrine glands
  • 5.
  • 6.
  • 7.
  • 8.
  • 9.
  • 11.
  • 13.
  • 15.
  • 16. Endocrine glands • 1 Pineal gland • 2 Pituitary gland • 3 Thyroid gland • 4 Thymus • 5 Adrenal gland • 6 Pancreas • 7 Ovary (female) • 8 Testis (male)
  • 17. Hypophysis cerebri – Pituitary gland
  • 18. • Master gland: Control other endocrine glands
  • 19. Facts • Pear shaped gland • Measures 1 – 1.5cm in diameter • 6mm height & 9mm breath • Wt: 500 to 900 mg (pregnancy : 1g) • Larger in women • Attaches with hypothalamus by stalk – infundibulum and both acts as a single unit
  • 20. Location: Small depression of sphenoid bone, known as sella turcica – hypophyseal fossa
  • 21. Anatomical relations: • Anteriorly – Anterior inter cavernous sinus • Posteriorly – posterior inter cavernous sinus and posterior wall of the sella turcica • Superiorly – fold of dura mater that covers the pituitary gland, optic chiasm and hypothalamus • Inferiorly – sphenoid sinus • Laterally – cavernous sinuses.
  • 22. PI = pituitary gland, AICS, PICS = Anterior and posterior intercavernous sinuses, SPH = sphenoid sinus.
  • 23.
  • 24.
  • 25.
  • 26.
  • 27. Anterior Lobe - 3 parts: • Pars Anterior / distalis – largest part, secretes hormones under the control of the hypothalamus, via neurotransmitters • Pars tuberalis – upwards extension of pars anterior • Pars intermedia – thin layer that separates the pars anterior from the posterior lobe of pituitary.
  • 28.
  • 29.
  • 30. Anterior lobe – Adeno hypophysis (75%) 5 types of glandular tissue 1. Somatotrophs 2. Thyrotrophs 3. Gonadotrophs 4. Lactotrophs 5. Corticotrophs
  • 31.
  • 32.
  • 33. Posterior pituitary – neurohypophysis ( 25% ) • It is an extension of hypothalamus • Contains neural tissue • It does not produce hormones, but the hormones produced by the hypothalamus travel to the posterior pituitary stored and released when needed • Oxytocin and ADH.
  • 34. Posterior Lobe / neurohypophysis: .
  • 35.
  • 36. • Neurons have their cell bodies in the supra optic para ventricular nuclei of hypothalamus and their axon forms a bundle known as hypothalamo hypophyseal tract • Posterior piyuitary hormones are produced in the nerve cell bodies transported through theses axons and stored in vesicles in axon terminals in the posterior Pituitary. • Release by exocytocis is trigerred by nerve impulse from hypothalamus
  • 37.
  • 38.
  • 39. Melanocyte Stimulating Hormone • Secreted by the intermediate lobe of the pituitary gland and function primarily on skin darkening by stimulating the production and release of melanin • Also produced by hypothalamus and skin cells. • Protecting the skin from UV rays
  • 40.
  • 41.
  • 42. Blood supply: Anterior Pituitary • Superior hypophyseal artery first forms a capillary network around the hypothalamus – blood from this network is then transported the anterior pituitary that allows the communication via the release of neurotransmitters into the bloodstream. Posterior Pituitary • Superior hypophyseal artery, infundibular artery and inferior hypophyseal artery. • Venous drainage - Anterior and posterior hypophyseal veins