The document provides information on various factors that can contribute to toxicity and poor methylation, including where one lives, exposures to toxins, diet, medications, and genetic predispositions. It also includes quizzes to assess one's methylation status and risk level. Recommendations are given for improving methylation and detoxification, such as following the UltraMind Solution program, consuming a plant-based diet with detoxifying foods and supplements, and addressing stress and negative emotions.

1. Holli Oram, MS

2.  Living in Utah sets us up! (see blog post—at least
3 Hit categories during Winter inversions)
 Pesticide exposure (even via foods), tainted well
water, some drinking water (pg. 197 LAoT)
 Occupational or accidental exposure to toxic
substances (pg. 210 and 396-401 LAoT for charts)
 Burning candles with metal wicks
 Cleaning products & other unhealthy things: new
carpet, new paint, make-up, smoking, etc.
 Food- the obvious & sometimes food intolerances

4.  Hard stool or difficult to pass BMs.
 Constipation (should have daily BMs.)
 Infrequent urination that is dark and a strong
odor.
 Almost never break into a sweat.
 Have one or more of the following symptoms:
 Fatigue, muscle aches, headaches, concentration and
memory problems.
* Have fibromyalgia or chronic fatigue syndrome.

5.  I drink unfiltered water or from plastic bottles.
 The clothes I wear are dry cleaned.
 I work/live in a building w/poor ventilation or
windows that won’t open.
 I live(d) in/near a large urban/industrial area.
 I use household or lawn and garden chemicals
to treat for bugs or use an exterminator.
 I have mercury fillings in my teeth.
 I eat (or ate) large fish or tainted fish.

6.  I am bothered by 1 or more of the following:
the smell of gas or diesel fumes, perfumes, new
cars, fabric stores, dry cleaning, hair spray,
soaps, detergents, tobacco smoke, chlorinated
water, other strong smells.
 I have a negative reaction when I consume
foods with MSG, sulfites, sodium benzoate, red
wine, cheese, bananas, chocolate, alcohol,
garlic, onions, caffeine (wired up or feel
anxious, palpitations, sweating, dizziness.)

7.  I regularly have any of the following: Tylenol
(acetaminophen), acid-blocking drugs
(Tagamet, Zantac, Pepcid, Prilosec, Prevacid),
hormone-modulating medications of any kind
(birth-control, hormones, prostate medication),
ibuprofen or naproxen, medications for colitis,
Chrone’s disease, recurrent headaches, allergy
symptoms, nausea, diarrhea, or indigestions
 I have had jaundice for any reason or have
Gilbert’s syndrome (Elevation of billirubin.)

8.  I live on the Wasatch Front.
 I have a family history of Parkinson’s
Alzheimer’s ALS, or other motor neuron
diseases or multiple sclerosis.
 SCORE: 0-6 You may have low levels of
toxicity, follow Nedley/UltraMind program.
 7-9: You may have moderate toxicity (do
program and self-care steps in UltraMind.)
 10+ May have severe toxicity: Do all and see
things to discuss w/functional medicine doctor

10.  “Almost every mental disorder and
neurodegenerative disease from
depression to Alzheimers, from
ADHD to autism, from Parkinson’s
to bipolar disease can be improved
by fixing problems with methylation
and sulfation trains.” Dr. Hyman, The
UltraMind Solution

11.  Hyman’s methylation quiz:
 ___I eat any kind of animal protein more than 5 times a week (i.e. any
meat, eggs, milk products. Etc.)
 ___ I eat more than 1-2 foods a week with hydrogenated fats. (“0 grams”
is misleading!)
 ___ I have servings of animal protein greater than 4-6 ounces (the size of
the palm of your hand.)
 ___ I eat less than 1 cup of dark leafy green vegetables a day.
 ___ I eat fewer than 5-9 servings of veggies and fruit a day. (1/2 c= srvng)
 ___ I have more than 3 alcoholic servings a week.
 ___ I have depression, depressed mood or other mood or behavior
disorders.
 ___ I have a history of heart attack or other heart disease.
 ___ I have a history of stroke.
 ___ I have a history of cancer (especially colon, cervix, breast.)

12.  ___ I have a history of abnormal PAP tests (cervical dysplasia.)
 ___ I have a history of birth defects in offspring (spina bifida, neural tube
defects, or Down syndrome.)
 ___ I have a history of dementia.
 ___ I have a loss of balance of sensation in the feet.
 ___ I have a history of multiple sclerosis or other diseases with nerve
damage.
 ___ I have a history of carpal tunnel syndrome.
 ___ I do not take a multi-vitamin.
 ___ I am over 65 years old.
 Key: 0-8: Low level problem, follow UltraMind/Nedley program
 9 and above: You may have a severe problem and may need medical care
from a doctor well-versed in functional medicine &/or nutrition.

14. Sulphur
soaks up
toxins
Production of
Glutathione is
critical to
good health!

16. Hyman on Genes and depression What it does How to improve its function
MTHFR Controls methylation High doses of folic acid or methyl-folate
Apolipoprotein E4 Carries cholesterol & heavy metals Whole foods, low-glycemic-load diet; exercise
GSTM, GTSP Helps body detoxify & produce glutathione Adequate intake of B12,B6, folate, & amino acids
w/sulfur like NAC; eat 2 cups of cruciferous veggies
a day
CETP Transports cholesterol away from arteries Whole foods, low-glycemic-load diet; exercise
COMT Metabolizes neurotransmitters & hormones via
methylation
Adequate intake of B6, B12, and folate
SOD-2 Powerful intracellular antioxidant Take zinc, manganese & copper (multi-vitamin) &
plenty of phytonutrient antioxidants
Multi-gene disorders Interaction between many genes UMS pg. 223-4. Turn off bad genes through diet,
nutrition, 2 cups kale or cabbage

17.  Toxic exposure + poor methylation +
poor sulfation + genetic pre-dispositon (+
hormones (ie. strong sugar addict-
hormone connection) + ACEs, etc.) =
Low functioning
neurotransmitters
 Predisposed to ADDICTIONS

19. Brain Chemistry at a Glance (from Ten Ways to Balance Your Brain Chemistry by Cristine Price, M.S.)
Neuro-Chemical Function/ Experience Mimicked by/Counterfeits Facilitated/ Supported by
Norepinephrine Stimulant/ Energy/ Wakefulness/ Focus
(concentration)
Caffeine/ Amphetamines High pH diet/SAM-e
/Exercise/ Passion for Life
[Endorsing]
GABA (see Hyman
quiz, pg. 106-7 &
nutrition)
Depressant/ Sleep/ Relaxation Sleeping pills/ Alcohol/
Benzodiazepines
Benadryl/ GABA/
Meditation/ Yoga, Deep
Breathing [Endorsing], Q-
96
Serotonin (see Hyman
quiz, pg. 103 &
nutrition)
Well Being/ Mood Stabilizer/
Contentment [Calmness]/ Inclinations/
[Patience]/ [Sleep]/
Comfort foods/ SSRIs/
Marijuana
5-HTP/ Mindful Eating/
Cal-Mag Fizz/ Positive
Affirmations/ [Endorsing],
Q-96

20. Beta-Endorphins Pain relief/ Euphoria/ Comfort/
Numbness
Sugar/ Pain pills/ Narcotics/
Morphine
High Protein Diet (?)/
EFT/ Theta Waves/
Massage/ Spiritual Highs
Dopamine (see Hyman
quiz, pg. 101 &
nutrition)
Stimulant + Euphoria/ Fantasy/
Pleasure Rush/ [Balance & Controlled
Movement/ Motivation Drive]/
Regulation of brain’s information
flow]
Chocolate/ Cocaine/ Sex/ Thrill
Seeking
DL Phenylalanine/
Intense Exercise/ Sensory
Enhancement, Q-96
[Norepinephrine and
Dopamine]
Attention Information from The Lost Art
of Thinking, Dr. Nedley
[High Tyrosine diet, low
animal protein diet, pg.
149 LAoT]
[Serotonin and
Dopamine]
Appetite “ “

22.  The entire Nedley program! Water intake, deep
breathing, contrasting showers, plant-based diet,
exercise, sunlight, melatonin-friendly sleep, etc. etc. etc.
(see blog posts)
 What Dr. Hyman did: Detoxifying foods, supplements
(like green drinks, herbs (tumeric, curry, milk thistle),
intraveneous glutathione and vitamin C, metal
chelators, and saunas (or can use steam rooms.)
 Dr. Nedley’s book: The Lost Art of Thinking
 Hyman book: The Blood Sugar 10-Day Detox Diet
 Dr. Elson Haas book: The False Fat Diet
 Clear Body, Clear Mind book: needs supervision

24.  Eat organic and clean meats if you eat meat
 True Hope, Equilib, Q-96 supplement
 Oil pulling (see my blog post)
 Remember that negative emotions can literally
be very toxic---use CBT, EFT, Emotional release
 Forgiveness work and prayer.
 Eden Energy medicine has various routines
that help the body detoxify.
 Acupuncture, moxibustion, homeopathics, etc.

26.  RDA approx. 48-60 g/day
 avocado = 10 g protein
 1 c. broccoli = 5 g
 1 c. spinach = 5 g
 2 c. cooked kale = 5 g
 1 c. boiled peas = 9 g
 1 c. sweet potato = 9 g
 1 c. soybeans = 28 g
 1 c. lentils = 18 g
 1 c. refried beans = 16 g
 1 c. hummus = 14.5 g
 1 c. pinto, kidney, black
beans = 13-15 g
 1 oz. peanuts = 6.5 g
 1 oz. cashews = 4.4 g
 1 oz. sesame seed = 7g
 ¼ c. walnuts = 5 g
 1 oz. pistachios = 4 g
 2 tbsp. almonds = 4 g
 Nut butters abt. 8 g per
2 tblspn.

27.  quinoa 1 c. = 9 g
 seitan (flavored wheat
gluten) 1 c. = 52 g
 Oatmeal 1 c. = 6 g
 Hemp powder 30 gm
= 11 g
 Other high protein
grains: amaranth,
bulgur, brown rice,
wheat germ and oat
bran