Gene Descriptions WormBase Workshop International Worm Meeting 2015

1. Community Curation of Gene Descriptions
Ranjana Kishore
WormBase@Caltech
Pasadena, California

2. Gene concise descriptions are snapshots of gene function
Key data: orthology, process, molecular function, tissue and sub-
cellular expression data (all from published papers).

3. Help us with writing and updating gene descriptions
Use our community curation system and participate in writing
gene descriptions!
Writing and updating gene descriptions are labor-intensive and time-consuming

4. How can you help with WormBase Gene descriptions?
-Write a new gene description (eg. for a newly published* gene).
-Update an old gene description with new published* data.
-Refine/Update our automated descriptions written by scripts (based on
orthology and gene ontology (GO) data previously curated in WormBase).
Example of an automated description:
“hmg-1.2 is an ortholog of human HMGB2 (high mobility group box 2),
HMGB1 (high mobility group box 1), HMGB3 (high mobility group box 3) and
HMGB4 (high mobility group box 4); hmg-1.2 is involved in cell fate
specification, Wnt signaling pathway, vulval development, positive
regulation of transcription from RNA polymerase II promoter and
hermaphrodite genitalia development; hmg-1.2 exhibits transcription
regulatory region DNA binding activity; hmg-1.2 is localized to the nucleus”.
*No meeting abstracts or Worm Breeder Gazette articles please

5. Using the Gene Description Submission Form
Step 1: Enter your name and e-mail address
Follow the links from here to this form

6. Step 2: Pick a gene and write a new description (if none)
or edit the existing gene description

7. Step 3: Enter references for the gene description
and then Preview and Submit
You just contributed a gene description!

8. Acknowledgements
Juancarlos Chan (Developing the form and software)
James Done (Automated descriptions project)
WormBase people at Caltech (For everything else!)