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A presentation by Rahul Kushwaha
B.C.A 2 B
Definition of
Superbug
An informal term for a bacterium that has become resistant
to antibiotics usually used to treat it, as Methicillin-
Resistant Staphylococcus Aureus (MRSA) or any
multiresistant bacterium.
"A drug-resistant superbug that spreads by skin contact is
infecting thousands of people across the US and may now
have reached Europe."
The history of discovering superbugs
NDM1 was discovered in India (New Delhi metallo-ß-lactamase-1).
The current situation
NDM1 now is world spread and has caused many deaths.
There are about 80,000 Chinese people dying for misusing of antibiotics
The superbugs problem is severe all over the world.
Scientists are still searching for the treatment.
About two years ago, on an extended visit to
India, she broke a thighbone, according to the
report. She had several hospitalizations in India
because of infections.
 When the patient was admitted to the Reno
hospital, health workers discovered that the
bacteria specimen tested was resistant to a class of
antibiotics called carbapenems— carbapenem-
resistant enterobacteria.
Lab results showed she was resistant to all 14
drugs they tested.
 Further tests at the CDC lab showed resistance
to 26 antibiotics. She died in September of
multiple organ failure and sepsis.
NDM-1 refers to a gene that is carried by some
bacteria. A bacterial strain that carries the NDM-1
gene will be resistant to even some of the strongest
antibiotics. There are no current antibiotics to combat
bacteria that have the NDM-1 gene, and this makes it
potentially very dangerous.
NDM-1 stands for New Delhi metallo-ß-lactamase-1.
It was first isolated in a Swedish patient of Indian
origin who travelled to India in 2008. What led to the
emergence of NDM-1 in India is not clear.
It has been found to be widespread in India, and by
2015, it had been detected in more than 70 countries
worldwide.
 The DNA code for NDM-1 can jump from one
bacteria strain to another through a process
known as horizontal gene transfer (HGT).
 If NDM-1 jumps to a bacterium that is already
antibiotic-resistant, some dangerous infections
could emerge, which would spread rapidly
between people. These infections might be
untreatable.
▶ Though it relies much on the development of
science, it is more effective than developing new
antibiotics to treat new superbugs. It is a vicious
circle and infinite. New antibiotics can motivate
new superbugs. We will be caught in the circle
for centuries.
Avoid the misuse of antibiotic-overuse and abuse
of antibiotic
When treat ordinary maladies, no need to
prescribe antibiotics.
Strengthen disinfection in hospital
 Now UN declare that the superbug is the most
important factor for the world for the death of
people died in future after the world war.
 Currently 139 countries is affected by Super
bug.
 In India In the year 2050 the number of people
dead due to super bug will be 1 crore per year.
THE SUPER BUG.pptx

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THE SUPER BUG.pptx

  • 1. A presentation by Rahul Kushwaha B.C.A 2 B
  • 2. Definition of Superbug An informal term for a bacterium that has become resistant to antibiotics usually used to treat it, as Methicillin- Resistant Staphylococcus Aureus (MRSA) or any multiresistant bacterium. "A drug-resistant superbug that spreads by skin contact is infecting thousands of people across the US and may now have reached Europe."
  • 3. The history of discovering superbugs NDM1 was discovered in India (New Delhi metallo-ß-lactamase-1). The current situation NDM1 now is world spread and has caused many deaths. There are about 80,000 Chinese people dying for misusing of antibiotics The superbugs problem is severe all over the world. Scientists are still searching for the treatment.
  • 4. About two years ago, on an extended visit to India, she broke a thighbone, according to the report. She had several hospitalizations in India because of infections.  When the patient was admitted to the Reno hospital, health workers discovered that the bacteria specimen tested was resistant to a class of antibiotics called carbapenems— carbapenem- resistant enterobacteria. Lab results showed she was resistant to all 14 drugs they tested.  Further tests at the CDC lab showed resistance to 26 antibiotics. She died in September of multiple organ failure and sepsis.
  • 5.
  • 6.
  • 7. NDM-1 refers to a gene that is carried by some bacteria. A bacterial strain that carries the NDM-1 gene will be resistant to even some of the strongest antibiotics. There are no current antibiotics to combat bacteria that have the NDM-1 gene, and this makes it potentially very dangerous. NDM-1 stands for New Delhi metallo-ß-lactamase-1. It was first isolated in a Swedish patient of Indian origin who travelled to India in 2008. What led to the emergence of NDM-1 in India is not clear. It has been found to be widespread in India, and by 2015, it had been detected in more than 70 countries worldwide.
  • 8.
  • 9.  The DNA code for NDM-1 can jump from one bacteria strain to another through a process known as horizontal gene transfer (HGT).  If NDM-1 jumps to a bacterium that is already antibiotic-resistant, some dangerous infections could emerge, which would spread rapidly between people. These infections might be untreatable.
  • 10. ▶ Though it relies much on the development of science, it is more effective than developing new antibiotics to treat new superbugs. It is a vicious circle and infinite. New antibiotics can motivate new superbugs. We will be caught in the circle for centuries.
  • 11. Avoid the misuse of antibiotic-overuse and abuse of antibiotic When treat ordinary maladies, no need to prescribe antibiotics. Strengthen disinfection in hospital
  • 12.  Now UN declare that the superbug is the most important factor for the world for the death of people died in future after the world war.  Currently 139 countries is affected by Super bug.  In India In the year 2050 the number of people dead due to super bug will be 1 crore per year.