1. The incidence is about 200 cases per 100,000 patients per year.
Breaks in the skin between the toes are perhaps the most important potential sites
for pathogen entry.

2. In mild cases, blood cultures are positive in less than 5 percent of cases. Culture
results from needle aspiration vary from ≤5 to 40%, while culture of punch biopsy
specimens yields a pathogen in 20-30% of cases.

3. Cellulitis pathogens implicated in special clinical circumstances include: pasteurella
multocida and capnocytophaga canismorsus (dog and cat bites), pseudomonas
aeruginoasa (diabetics).

4. Purulent and non-purulent: These terms are designations within the 2011 Infectious
Disease Society of America clinical practice guidelines for methicillin-resistant S.
aureus (MRSA). The use of these terms in the guidelines suggests that an infection
involving purulence is potentially attributable to S. aureus, which should be reflected
in the choice of empiric antimicrobial therapy.

5. In a study including 422 patients with purulent soft tissue infection, MRSA was the
dominant organism, isolated from 59% patients, followed by MSSA (17%); beta-hemolytic
streptococci accounted 2.6%.

6. MRSA Risk factors include: recent hospitalization, residence in long term care facility,
HD, Diabetes, IV drug use, recent antibiotic therapy, incarceration, HIV

7. MRSA Risk factors include: recent hospitalization, residence in long term care facility,
HD, Diabetes, IV drug use, recent antibiotic therapy, incarceration, HIV