Norton Medical and Scientific Research & Biotechnology is dedicated to publishing the latest news, mainly on, medical research and biotechnology advancements.
First ever digital model of an entire organism created
1.
2. First Ever Digital Model of an Entire Organism
Created
Scientists from J. Craig Venter Institute and Stanford University
have successfully built a computational model of an entire
organism in computer software -- for the first time ever.
This incredible feat will provide the bioengineering researchers a
global analysis of the allocation and use of energy in the cell
along with identifying usual molecular pathologies behind single-
gene disruption characteristics.
The simulation of an organism will undoubtedly help researchers
in better understanding biology, cells in particular. Moreover, it
could aid in speeding up research or permitting a test that will
not be possible in actual conditions.
According to the team's lead scientist, «If you use a model to
guide your experiments, you're going to discover things faster.
We've shown that time and time again.»
3. The scientists used data from more than 900 scientific papers
written about the bacterium that covered all molecular
processes taking place within the organism's lifecycle. Grouped
into 28 different modules are the resulting 1,900 resulting
parameters. Modules are responsible for their respective
biological process and is controlled by its own algorithm.
Moreover, modules can communicate amongst each other,
replicating the actual processes inside the living bacterium.
The reason for choosing the M. genitalium as the subject is
because of its size -- it has the smallest known genome (with 521
genes in a circular chromosome of almost 583,000 base pairs)
among any free-living organism that can constitute a cell. It is
also the second-smallest bacterium, next to the more
conventional lab bacterium E. coli.
already when you consider that it is a very tiny organism.
4. In order to simulate just one cell division, a cluster of 128
computer units running for 10 hours were used to generate the
data on 25 types of molecules involved in the cell's life cycle. The
resulting data amounts to 500Mb, which could not look like much
but is actually very big already when you consider that it is a very
tiny organism.
«Right now, running a simulation for a single cell to divide only
one time takes around 10 hours and generates half a gigabyte of
data. I find this fact completely fascinating, because I don't
know that anyone has ever asked how much data a living thing
truly