protein

1. QUARTENARY STRUCTURE OF
PROTEIN
Nur Farra Najwa Binti Abdul
Azim
– 082015100035

2. OBJECTIVE
 Able to recognise the quartenary structure
 Identifies the bond and forces in quartenary
structure
 Able to give example of quartenary structure
 Components of quartenary structure

3. INTRODUCTION
 4th level of protein structure
 Aggregation of polypeptides to form one
FUNCTIONAL protein which gives shape and
structure.
 Once dissociate (denaturation) from
quartenary structure, no more functional and
structural of protein

5. COMPONENT THAT MAKE UP QUARTENARY
STRUCTURE
Quartenary
structure formed
by
Forces
Van der
waals
Between non
polar
Electrostatic
Between
polar
Bond
Hydrogen
Involve
hydrogen
atom
Bonds that exist
between the side
groups of
different chains.
http://www.chemistryexplained.com/Pr-Ro/Quaternary-Structure.html

6. QUARTENARY STRUCTURE
Chain /
subunit
polypeptide
QUARTENA
RY
Monomer
(1 Chain)
Dimer (2 Chain) =
CREATINE
KINASES
Tetramere (4 Chain) =
LACTATE
DEHYDROGENASES

7. QUARTENARY STRUCTURE
Homodimer Same polypeptide chain
Heterodimer Different 2 polypeptide chain

9. QUARTENARY STRUCTURE
Example :
HAEMOGLOBIN
MOLECULE
• 2 alpha chain
•2 beta chain
IMMUNOGLOBULIN
MOLECULE
•2 heavy chain
•2 light chain

10. SUMMARY

11. SUMMARY ( TAKE HOME NOTE )

12. THANK
YOU