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Brain Tumors: Malignant vs. Benign 
New Jersey CyberKnife outlines what you need to know about 
the difference between malignant versus benign brain tumors. 
99 Route 37 West, Toms River, NJ 08755 732-557-3120 NewJerseyCK.com
Please note: We encourage consumers to thoroughly review and understand 
all treatment options. The information presented here is not all-inclusive. 
Rather, it represents a starting point to learn more about medical conditions 
and treatment options. This is not intended as a substitute for medical advice 
from your professional healthcare provider. Contact your professional 
healthcare provider to find out if CyberKnife® treatment is right for you. 
Data source: American Cancer Society. 
99 Route 37 West, Toms River, NJ 08755 732-557-3120 NewJerseyCK.com
Brain Tumors Overview 
Brain tumors are masses of abnormal cells in 
the brain. Although brain tumors rarely 
spread to other parts of the body, most of 
them can spread through the brain tissue. 
Tumors that start in the brain (primary brain 
tumors) are not the same as tumors that 
start in other areas of the body and then 
spread to the brain (metastatic or 
secondary brain tumors). In adults, 
metastatic tumors to the brain are actually 
more common than primary brain tumors. 
The main concerns with brain and spinal 
cord tumors are how readily they spread 
through the rest of the brain or spinal cord 
and whether they can be removed and not 
come back. 
The general symptoms caused by a 
brain tumor depend on where the 
tumor is. Symptoms may include: 
¤ Headaches, seizures or 
balance problems 
¤ Trouble speaking 
¤ A change of mood such as 
depression 
¤ A change in personality 
¤ Weakness, stiffness or paralysis in 
part of the body 
¤ Changes in vision, hearing, or 
other senses 
¤ Tremors or involuntary 
movements 
99 Route 37 West, Toms River, NJ 08755 732-557-3120 NewJerseyCK.com
Benign (Non-Cancerous) Brain Tumors 
In most other parts of the body, benign tumors do not grow 
into nearby tissues or spread to distant areas, so in other 
parts of the body they are almost never life threatening. 
However benign brain tumors can, as they grow, press on 
and destroy normal brain tissue, causing damage that is 
often disabling. 
Benign brain tumors include: 
¤ meningioma 
¤ acoustic neuroma 
¤ pituitary adenoma 
¤ craniopharyngioma. 
99 Route 37 West, Toms River, NJ 08755 732-557-3120 NewJerseyCK.com
Malignant (Cancerous) Brain Tumors 
One of the main reasons malignant tumors are so dangerous is because 
they have a propensity to grow. Typical malignant brain tumors include 
glioblastoma, anaplastic astrocytoma, primary CNS lymphoma and 
medulloblastoma. 
The American Cancer Society’s 2014 estimates for brain and spinal cord 
tumors in the United States include both adults and children: 
¤ About 23,380 malignant tumors of the brain or spinal cord (12,820 in males 
and 10,560 in females) will be diagnosed. 
¤ Overall, the chance that a person will develop a malignant tumor of the 
brain or spinal cord in his or her lifetime is less than 1% (about 1 in 140 for a 
man and 1 in 180 for a woman). 
99 Route 37 West, Toms River, NJ 08755 732-557-3120 NewJerseyCK.com
Brain Tumor Treatment Options 
Treatment is based on the type of tumor and other factors, and 
sometimes more than one type of treatment is used. Doctors plan 
each person’s treatment individually to give them the best 
chance of treating the cancer while limiting the side effects as 
much as possible. 
¤ Surgery 
¤ Stereotactic Radiosurgery (CyberKnife® or GammaKnife®) 
¤ Radiation Therapy 
¤ Chemotherapy 
¤ Targeted Therapy 
99 Route 37 West, Toms River, NJ 08755 732-557-3120 NewJerseyCK.com
Brain Tumors + CyberKnife Treatment 
CyberKnife has the ability to treat acoustic neuromas, 
brain metastases, gliomas, meningiomas and pituitary 
adenomas with stereotactic radiosurgery. 
Unlike some radiosurgery systems, the CyberKnife 
doesn’t need an invasive head frame. Other 
radiosurgery systems are capable of high-dose 
radiation treatment with a variety of radiation sources. 
However, some use a metal frame attached to the 
patient’s skull with screws that immobilize the head to 
accurately target the tumor. 
Typically, treatment is completed in one session but 
could take up to five sessions depending on the 
individual diagnosis. Treatment procedures take about 
30 – 90 minutes, depending on the complexity of the 
tumors. 
99 Route 37 West, Toms River, NJ 08755 732-557-3120 NewJerseyCK.com
Treating Brain Tumors at 
New Jersey CyberKnife 
New Jersey CyberKnife expanded brain and spine tumor treatment 
expertise with the addition of Dr. John Lipani. A board-certified 
neurosurgeon, Dr. Lipani has treated more than 3,500 brain and spine 
tumor patients with CyberKnife technology. He is a nationally recognized 
specialist in the field of brain and spine stereotactic radiosurgery (SRS). 
99 Route 37 West, Toms River, NJ 08755 732-557-3120 NewJerseyCK.com
New Jersey CyberKnife 
Patient Testimonial 
New Jersey CyberKnife patient 
Laurel underwent three surgeries and 
conventional radiation therapy for a 
recurring meningioma before turning 
to CyberKnife treatment. 
“The New Jersey CyberKnife staff was 
very knowledgeable and made sure I 
was comfortable, even offering 
blankets during my treatment 
sessions,” Laurel said. “During my five 
treatments, I relaxed by listening to 
music, and I felt very comfortable with 
my knowledge of how the CyberKnife 
was going to move around me.” 
“After having undergone other treatments for 
her diagnosis, Laurel required a nonsurgical 
option. She, like many of our patients, was 
drawn to the convenience of CyberKnife 
treatment,” Dr. D’Ambrosio said. “Patients 
typically experience few to no side effects and 
can return to their daily routines immediately 
following treatment.” 
99 Route 37 West, Toms River, NJ 08755 732-557-3120 NewJerseyCK.com
Our Center 
New Jersey CyberKnife at the J. Phillip Citta Regional 
Cancer Center combines experienced physicians 
and the latest medical advances. Our state-of-the-art 
technology offers hope to patients in New Jersey 
and beyond. Medical Director Dr. David D’Ambrosio 
specializes in advanced radiation treatment and 
therapy options. His expertise includes intensity-modulated 
and stereotactic radiation therapies, 
including CyberKnife radiosurgery, head and neck 
cancer, prostate cancer and lung cancer. 
If you or a loved one is diagnosed with cancer, 
contact New Jersey CyberKnife to schedule a 
consultation with our physicians to determine the 
best next step for your treatment needs. 
Read Our 
Blog! 
Connect with us! 
99 Route 37 West, Toms River, NJ 08755 732-557-3120 NewJerseyCK.com

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New Jersey CyberKnife: Malignant vs. Benign Brain Tumors

  • 1. Brain Tumors: Malignant vs. Benign New Jersey CyberKnife outlines what you need to know about the difference between malignant versus benign brain tumors. 99 Route 37 West, Toms River, NJ 08755 732-557-3120 NewJerseyCK.com
  • 2. Please note: We encourage consumers to thoroughly review and understand all treatment options. The information presented here is not all-inclusive. Rather, it represents a starting point to learn more about medical conditions and treatment options. This is not intended as a substitute for medical advice from your professional healthcare provider. Contact your professional healthcare provider to find out if CyberKnife® treatment is right for you. Data source: American Cancer Society. 99 Route 37 West, Toms River, NJ 08755 732-557-3120 NewJerseyCK.com
  • 3. Brain Tumors Overview Brain tumors are masses of abnormal cells in the brain. Although brain tumors rarely spread to other parts of the body, most of them can spread through the brain tissue. Tumors that start in the brain (primary brain tumors) are not the same as tumors that start in other areas of the body and then spread to the brain (metastatic or secondary brain tumors). In adults, metastatic tumors to the brain are actually more common than primary brain tumors. The main concerns with brain and spinal cord tumors are how readily they spread through the rest of the brain or spinal cord and whether they can be removed and not come back. The general symptoms caused by a brain tumor depend on where the tumor is. Symptoms may include: ¤ Headaches, seizures or balance problems ¤ Trouble speaking ¤ A change of mood such as depression ¤ A change in personality ¤ Weakness, stiffness or paralysis in part of the body ¤ Changes in vision, hearing, or other senses ¤ Tremors or involuntary movements 99 Route 37 West, Toms River, NJ 08755 732-557-3120 NewJerseyCK.com
  • 4. Benign (Non-Cancerous) Brain Tumors In most other parts of the body, benign tumors do not grow into nearby tissues or spread to distant areas, so in other parts of the body they are almost never life threatening. However benign brain tumors can, as they grow, press on and destroy normal brain tissue, causing damage that is often disabling. Benign brain tumors include: ¤ meningioma ¤ acoustic neuroma ¤ pituitary adenoma ¤ craniopharyngioma. 99 Route 37 West, Toms River, NJ 08755 732-557-3120 NewJerseyCK.com
  • 5. Malignant (Cancerous) Brain Tumors One of the main reasons malignant tumors are so dangerous is because they have a propensity to grow. Typical malignant brain tumors include glioblastoma, anaplastic astrocytoma, primary CNS lymphoma and medulloblastoma. The American Cancer Society’s 2014 estimates for brain and spinal cord tumors in the United States include both adults and children: ¤ About 23,380 malignant tumors of the brain or spinal cord (12,820 in males and 10,560 in females) will be diagnosed. ¤ Overall, the chance that a person will develop a malignant tumor of the brain or spinal cord in his or her lifetime is less than 1% (about 1 in 140 for a man and 1 in 180 for a woman). 99 Route 37 West, Toms River, NJ 08755 732-557-3120 NewJerseyCK.com
  • 6. Brain Tumor Treatment Options Treatment is based on the type of tumor and other factors, and sometimes more than one type of treatment is used. Doctors plan each person’s treatment individually to give them the best chance of treating the cancer while limiting the side effects as much as possible. ¤ Surgery ¤ Stereotactic Radiosurgery (CyberKnife® or GammaKnife®) ¤ Radiation Therapy ¤ Chemotherapy ¤ Targeted Therapy 99 Route 37 West, Toms River, NJ 08755 732-557-3120 NewJerseyCK.com
  • 7. Brain Tumors + CyberKnife Treatment CyberKnife has the ability to treat acoustic neuromas, brain metastases, gliomas, meningiomas and pituitary adenomas with stereotactic radiosurgery. Unlike some radiosurgery systems, the CyberKnife doesn’t need an invasive head frame. Other radiosurgery systems are capable of high-dose radiation treatment with a variety of radiation sources. However, some use a metal frame attached to the patient’s skull with screws that immobilize the head to accurately target the tumor. Typically, treatment is completed in one session but could take up to five sessions depending on the individual diagnosis. Treatment procedures take about 30 – 90 minutes, depending on the complexity of the tumors. 99 Route 37 West, Toms River, NJ 08755 732-557-3120 NewJerseyCK.com
  • 8. Treating Brain Tumors at New Jersey CyberKnife New Jersey CyberKnife expanded brain and spine tumor treatment expertise with the addition of Dr. John Lipani. A board-certified neurosurgeon, Dr. Lipani has treated more than 3,500 brain and spine tumor patients with CyberKnife technology. He is a nationally recognized specialist in the field of brain and spine stereotactic radiosurgery (SRS). 99 Route 37 West, Toms River, NJ 08755 732-557-3120 NewJerseyCK.com
  • 9. New Jersey CyberKnife Patient Testimonial New Jersey CyberKnife patient Laurel underwent three surgeries and conventional radiation therapy for a recurring meningioma before turning to CyberKnife treatment. “The New Jersey CyberKnife staff was very knowledgeable and made sure I was comfortable, even offering blankets during my treatment sessions,” Laurel said. “During my five treatments, I relaxed by listening to music, and I felt very comfortable with my knowledge of how the CyberKnife was going to move around me.” “After having undergone other treatments for her diagnosis, Laurel required a nonsurgical option. She, like many of our patients, was drawn to the convenience of CyberKnife treatment,” Dr. D’Ambrosio said. “Patients typically experience few to no side effects and can return to their daily routines immediately following treatment.” 99 Route 37 West, Toms River, NJ 08755 732-557-3120 NewJerseyCK.com
  • 10. Our Center New Jersey CyberKnife at the J. Phillip Citta Regional Cancer Center combines experienced physicians and the latest medical advances. Our state-of-the-art technology offers hope to patients in New Jersey and beyond. Medical Director Dr. David D’Ambrosio specializes in advanced radiation treatment and therapy options. His expertise includes intensity-modulated and stereotactic radiation therapies, including CyberKnife radiosurgery, head and neck cancer, prostate cancer and lung cancer. If you or a loved one is diagnosed with cancer, contact New Jersey CyberKnife to schedule a consultation with our physicians to determine the best next step for your treatment needs. Read Our Blog! Connect with us! 99 Route 37 West, Toms River, NJ 08755 732-557-3120 NewJerseyCK.com