A simplified view of Victor Dzau´s cardiovascular continuum

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By Luis Miguel Ruilope, MD, Professor, Internal Medicine, Complutense University, Head of the Hypertension Unit, 12 de Octubre Hospital, Madrid, Spain.

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  • The animation shows that the earlier the intervention, the greater the protection it affords.
  • The animation shows that the earlier the intervention, the greater the protection it affords.
  • The size of the three stages refers to the size of the population in each stage. The biggest section is stage 1 and the smallest section is stage 3. However, it is stage 3 that has the highest intervention cost even though it accounts for only some 25% of deaths. Proper stratification of risk in stage 1 by identifying cardiovascular and renal risk factors and providing early detection of target organ damage will enable interventions, including those for cardiometabolic risk, to be more effective and more comprehensive.
  • A simplified view of Victor Dzau´s cardiovascular continuum

    1. 1. A Simplified View of Victor Dzau´s Cardiovascular Continuum Luis Miguel Ruilope, MD Head of Hypertension Unit 12 de Octubre Hospital, Madrid, Spain
    2. 2. Cardio-renal Continuum REGRESS RETARD Target organ damage Asymptomatic Target organ damage Symptomatic Death CKD New risk factors Risk factors Cardiometabolic risk PREVENT Atherosclerosis ESRD Source: International Chair on Cardiometabolic Risk www.cardiometabolic-risk.org CKD : chronic kidney disease ESRD : end-stage renal disease
    3. 3. Cardio-renal Continuum REGRESS RETARD Target organ damage Asymptomatic CKD New risk factors Risk factors Cardiometabolic risk PREVENT Source: International Chair on Cardiometabolic Risk www.cardiometabolic-risk.org Target organ damage Symptomatic Death Atherosclerosis ESRD CKD : chronic kidney disease ESRD : end-stage renal disease
    4. 4. %EVENTS vs. COST %EVENTS 1 2 3 COST 75 % 25 %
    5. 5. <ul><li>www.cardiometabolic-risk.org </li></ul>

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