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3Osteosclerotic Vertebral
Lesions
CLINICAL IMAGAGING
AN ATLAS OF DIFFERENTIAL DAIGNOSIS
EISENBERG
DR. Muhammad Bin Zulfiqar
PGR-FCPS III SIMS/SHL
Fig SP 3-1 Osteoblastic metastases (ivory vertebrae). (A)
Carcinoma of the prostate. (B) Lymphoma.
• Fig SP 3-2 Paget's disease. Sclerotic vertebral
body with associated enlargement and cortical
thickening.4
• Fig SP 3-3 Chronic osteomyelitis. There is
destruction and collapse of bone with reactive
sclerosis and narrowing of two intervertebral disk
spaces. Note the poorly defined or fuzzy
diskovertebral junctions associated with this
pyogenic infection.2
• Fig SP 3-4 Osteoid osteoma. (A) Sclerotic lesion of
a pedicle (arrowhead). (B) Radiolucent nidus
(arrowhead) in an inferior articular process. (C)
Axial CT scan clearly shows the radiolucent nidus
(arrowhead) in a transverse process.2
• Fig SP 3-5 Mastocytosis. (A) Frontal and (B)
lateral radiographs of the thoracic region of
the spine show focal osteosclerotic lesions
associated with paravertebral swelling.2
• Fig SP 3-6 Osteopoikilosis. Multiple sclerotic
foci in the margins of the vertebral bodies and
posterior elements.2
• Fig SP 3-7 Melorheostosis. (A, B, and C) Three
radiographs of the axial skeleton show
hyperostosis and enostoses involving the upper
right ribs, the thoracic and lumbar vertebrae, the
sacrum, and the ilium. Quadriparesis developed
in this 21-year-old man because of a diffuse
intramedullary lipoma in the spinal cord.2
• Fig SP 3-8 Congenital stippled epiphyses.
Multiple, small punctate calcifications of
various sizes involve virtually all the epiphyses
in this view of the chest and upper abdomen.
• Fig SP 3-9 Tuberous sclerosis. Left oblique view
shows a homogeneously dense left pedicle and
superior articular facet (arrow). This was an
incidental finding on excretory urography.2
3 osteosclerotic vertebral lesions
3 osteosclerotic vertebral lesions

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3 osteosclerotic vertebral lesions

  • 2. CLINICAL IMAGAGING AN ATLAS OF DIFFERENTIAL DAIGNOSIS EISENBERG DR. Muhammad Bin Zulfiqar PGR-FCPS III SIMS/SHL
  • 3. Fig SP 3-1 Osteoblastic metastases (ivory vertebrae). (A) Carcinoma of the prostate. (B) Lymphoma.
  • 4. • Fig SP 3-2 Paget's disease. Sclerotic vertebral body with associated enlargement and cortical thickening.4
  • 5. • Fig SP 3-3 Chronic osteomyelitis. There is destruction and collapse of bone with reactive sclerosis and narrowing of two intervertebral disk spaces. Note the poorly defined or fuzzy diskovertebral junctions associated with this pyogenic infection.2
  • 6. • Fig SP 3-4 Osteoid osteoma. (A) Sclerotic lesion of a pedicle (arrowhead). (B) Radiolucent nidus (arrowhead) in an inferior articular process. (C) Axial CT scan clearly shows the radiolucent nidus (arrowhead) in a transverse process.2
  • 7. • Fig SP 3-5 Mastocytosis. (A) Frontal and (B) lateral radiographs of the thoracic region of the spine show focal osteosclerotic lesions associated with paravertebral swelling.2
  • 8. • Fig SP 3-6 Osteopoikilosis. Multiple sclerotic foci in the margins of the vertebral bodies and posterior elements.2
  • 9. • Fig SP 3-7 Melorheostosis. (A, B, and C) Three radiographs of the axial skeleton show hyperostosis and enostoses involving the upper right ribs, the thoracic and lumbar vertebrae, the sacrum, and the ilium. Quadriparesis developed in this 21-year-old man because of a diffuse intramedullary lipoma in the spinal cord.2
  • 10. • Fig SP 3-8 Congenital stippled epiphyses. Multiple, small punctate calcifications of various sizes involve virtually all the epiphyses in this view of the chest and upper abdomen.
  • 11. • Fig SP 3-9 Tuberous sclerosis. Left oblique view shows a homogeneously dense left pedicle and superior articular facet (arrow). This was an incidental finding on excretory urography.2