The Michigan State University In Vivo Facility aims to enable life sciences research by providing high-quality animal testing services. It offers both standard and specialized pharmacology assays, drug discovery/development services, and medical device testing to support academia and industry. The facility has experienced staff with drug development expertise who can perform a range of in vivo tests in normal and disease models across multiple therapeutic areas like cardiovascular, infectious disease, and oncology. Custom evaluations and animal models are developed to meet unique customer needs.

1. Michigan State University
In Vivo Facility

2. OUR MISSION
To enable life sciences and
biotechnology research by providing
high quality standard and specialized
in vivo pharmacology assays,
investigative drug
discovery/development services,
medical device testing, and
education.

3. OVERVIEW
• A University based fee for service
organization focused on timely
delivery of in vivo pharmacology data
and analysis
– Support academia and the private sector
– Provide internal resource for academic in
vivo activities in support of drug
discovery/development
– Ex-pharma colleagues who have
significant drug development expertise

4. WHO WE ARE:
• Marc Bailie, DVM, PhD, DSP
• Teresa Krieger-Burke, DVM, PhD
• Emily Nolan, DVM
• Matt Bernard, PhD
• Vicki Ruggiero, MPH, LVT
• Mary Isaac, BS, LVT
• Heidi Ball, BS
• Extensive network of participating
scientists across Michigan State
University

5. OUR SERVICES
Each customer's requirements are
unique. We develop customized
evaluations and models that address
specific needs.

6. OUR SERVICES
• Early (Non-GLP) Safety Pharmacology and General
Toxicology
• Testing in Normal and Disease Models
– Pharmacokinetics
– Cardiovascular
• Rodent Echo with Vevo 2100 high resolution ultrasound
– Infectious Disease
– Immunopharmacology
– CNS
– Pulmonary
– Renal
– Gastrointestinal
– Stroke Models
– Xenograft Tumor Efficacy Testing

7. OUR SERVICES
• http://invivo.phmtox.msu.edu/services.html for
more information on capabilities and
models
• Customized models and evaluations
developed to address specific
individual investigator needs