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AEFI : Hazards of Immunisation
1. Dr Md Tanwir Alam, MD
Assistant Professor, Dept. of PCM,
Govt. Tibbi College & Hospital, Patna
Tanveernium@gmail.com
ADVERSE EVENTS
FOLLOWING
IMMUNIZATION
(AEFI)
2. No immune response is
entirely free from the
risk of adverse
reactions or remote
sequalae.
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3. Old term ≈ AEPI
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18. Coincidental events
▪ Occasionally – may occur totally unconnected with
vaccine
▪ Underlined congenital & neurological condition
▪ Vaccine may shorten the incubation period (and
produce disease) of the harbouring disease
▪ Latent infection may converted to clinical attack
▪ e.g., provocative polio after DPT or DT administration
against diphtheria).
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20. Use of improperly sterilized syringes and
needles carry the hazard of hepatitis B
virus, and Staphylo - and Streptococcal
infection
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