3. Patient Presentation
Female patient 43 years old admitted emergency department on 26/9/20210 .
Past history : pt known to be DM type 1 on insulin , not HTN .
Clinical presentation :
Pt was dysnea , tachypnea , cough of 3 dasys .
Fever of 3 days , general fatigue .
Pt was conscious alert , GCS : 15/15
4. Vital signs
Blood pressure : 120/ 80
Pulse : 95 / min
temp : 38
R R : 24 /min
RBS : 300 mg / dl
Oxygen saturation : 82 % on room air
5. Investigtion
Imaging
CT chest :
Bil lung infeltrations , Ground Glass Opocities , Corad 4 .
EKG : normal sinus rhythm.
Abd U/ S : normal , fatty liver .
6. Labs
CBC:
HB : 9mg / dl , TLC : 2.8 , Lymph : 1.1 , PLT : 75
S Creatinine : 0.9 , S Urea : 32
ALT : 21 , AST : 19
T protein : 7 Albumin : 3.2
T bilirubin : 0.4 , D bilirubin : 0.1 INR : 1
D Dimer : 1.4 , S Ferritin : 1000
Na : 138 , K : 3.9 , Ionized Ca : 0.9
CRP : 77 , HBA1C : 7.5
ABG : PH : 7.38 , Pco2 : 40 , PO2 : 55 , HCO3 : 22
PCR was done on admission and was positive later
7. Management
Oxygen therapy :
Pt was put on NR mask of 10 l oxygen , the saturation was 97 %
Prone Position :
Pt was on prone positin for 4 to 6 hours daily
Feeding protocol:
Low carb, low sugar diet , good hydration , high protein .
8. Treatment
Antibiotics :
Ceftriaxone : 2gm IV / 24 h
Xithrone 500 mg : 1 tab /24 orally .
Rrmedisvir : 200 mg IV loading then 100 mg daily for 5 days .
Anticoagulant : LMWH , prophylactic dose .
Steriods : Dexamethasone : 6 mg IV /24 h
Paracetamol : 500 mg orally / 8 h
Antitussive syrup / 8 h
Vitamins : zinc , cit c
Regular insulin / 6 h + lantus before sleeping
Vit B12 every other day IV
9. Consultations
Hematological consultations :
Pt show normochromic normocytic anemia with thrombocytopenia , for follow up ,
mostly related to Covid infection .
Pt received 2 units of P RBCs and 2 units of Plasma .
For reconsult after 3 days .
Internal medicine :
For control of Diabetes Melitus
10. Progression 1
On 2nd day of admission :
Pt was on NR mask of 10 l oxygen , saturation was 97 % , less tachypnea and
dysnea .
Vital signs : BP : 120/70 , Pulse :85 , Temp : 37.8 , RR : 22
ABG : PH : 7.39 , PCO2: 40 , PO2 : 60 , HCo3 : 22
Investigations : HB : 9.5 , PLT : 88 . TLC : 4.3
RBS : controlled
Others are withen normal .
11. Progression 2
On 3rd day of admission :
Pt was put on ventury 50 , 10 l , oxygen saturation was 94 % , less dysnea and
tachypnea .
Still in prone position .
Vital signs : BP : 120/75 , Pulse : 80/ min , RR : 20 , Temp : 37 .3
CBC : HB : 9.7 , PLT : 66 , TLc: 7.2
Creatine : 0.7 , Urea :22, INR : 1 , D Dimer : 1.2 S Ferritin : 774
RBS : between 140 and 200 during the day
12. Progression 3
On 5th day of admission :
Pt was put on ventury 40 , oxygen saturation was 94 %
Vital signs : BP : 120 / 80 , Pulse : 80/min , Temp : 37 , RR : 21
ABG : PH :7.4 , Pco2: 42 , PO2 : 63 , Hco3 : 23
CBC : HG : 9.5 , PLT 55 , TLC : 7.3
Other investigations are accepted
We start chest physiotherapy
Treatment : xithrone , remedisvir were stopped , steroid descalating to ½ amp / 24
h .
Contol of DM , Good diet and hydration .
13. Progresssion 4
On 7th day of admission:
We descalating oxygen requirement to ventury 31 , the oxygen saturation was 95 %
, less dysnea and tachypnea .
Vital signs : BP : 120 /75 , Temp : 37 .1 , RR : 18 , Pulse : 76/ min
ABG : PH : 7.4, Pco2 : 42 , PO2 : 65 , Hco3 : 22
CBC : HB : 9.3 , TLC 8 , PLT : 80 , Lymph : 2.3
UREA : 44, Creatine : 0.7 , NA : 134 , K : 3.7 , CRP : 24
D Dimer : 0.8 , S ferritin : 330 INR : 1.1
CT chest was done : improved
RBS : controlled , diet control , chest physiotherapy .
14. Progression 5
On 9th day of admission :
Oxygen requirement descend to simple mask of 8 l , oxygen saturation was 96 % .
Vital signs : BP : 120/80 , Pulse : 75 / min , Temp : 37 , RR: 18
ABG : PH: 7.4 , PCo2 : 39 , PO2 : 70 , HCo3 : 24
CBC : HB : 9.5 , TLC : 66 , TLC 7.5
Other investigations were normal
Treatment : stop ceftriaxone , change steroid to oral dose and start to descalating ,
continue antitussive and vit and insulin .
For follow up with heamatologist
Pt was discharged to ward on simple mask and discharged home after 5 dasys