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Mrs. Melisa Fernandes,
Lecturer
M.Sc.Nursing (Oncology)
1.Understand the significant cellular and
genetic events that cause cancer and clinical
features of neoplastic diseases.
2.Able to differentiate different types of cancer
 Neoplasia – abnormal proliferation of cells in
a tisssue or organ.(new growth) often termed
as tumor.
 Hyperplasia –Proliferation of cells within an
organ results in enlargement.(remains under
normal control.(reversible increase in the
number of cells)
 Metaplasia –the conversion of one cell type to
another cell type not usually found in the
involved tissue
 Hypertrophy - increase in cell size(due to
steroid therapy) resulting in an increase in
organ size.
 Dysplasia- cells are different from the tissue
of origin.(early form of precancerous
transformation)
 Carcinoma in situ –cancer in place. cells have
lost their tissue identity,rowth is rapid and
without regulation, however remains
localized.
 Invasive carcinoma – invading beyond the
original tissue layer ,able to spread to
another parts of the body
 Metaplasia – changes in response to chronic
physical or chemical irritation (smoking)
causes ciliated epithelium to be replaced by
simple squamous epithelium.
 The change is benign and reversible to
certain limit.
 Adenoma – collection of growth (oma) f
glandular origin. (may compress other
structure or produce large amount of
hormones. May become malignant called
Adeno carcinoma.
 Sarcoma –cancer that affects connective
,supportive and soft tisue (bone, cartilage,
muscle or fat)
 Osteosarcoma –bone
 Chondrosarcoma –cartilage
 Leiomyosarcoma –smooth muscle
 Atrophy – shrinkage of cell size
 Anaplasia – disorganized ,irregular cells that
have loss of differentiation.(undifferentiated
cells)
 Metastasis –malignant cells travel through
blood or lymph and invade other tissues and
organs
 Oncology –a branch of medicine that deals
with tumor
 Oncologist – a medical professional who
practices oncology .
Thank you

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Intoduction to oncology

  • 2. 1.Understand the significant cellular and genetic events that cause cancer and clinical features of neoplastic diseases. 2.Able to differentiate different types of cancer
  • 3.  Neoplasia – abnormal proliferation of cells in a tisssue or organ.(new growth) often termed as tumor.  Hyperplasia –Proliferation of cells within an organ results in enlargement.(remains under normal control.(reversible increase in the number of cells)
  • 4.  Metaplasia –the conversion of one cell type to another cell type not usually found in the involved tissue  Hypertrophy - increase in cell size(due to steroid therapy) resulting in an increase in organ size.
  • 5.  Dysplasia- cells are different from the tissue of origin.(early form of precancerous transformation)  Carcinoma in situ –cancer in place. cells have lost their tissue identity,rowth is rapid and without regulation, however remains localized.
  • 6.  Invasive carcinoma – invading beyond the original tissue layer ,able to spread to another parts of the body
  • 7.  Metaplasia – changes in response to chronic physical or chemical irritation (smoking) causes ciliated epithelium to be replaced by simple squamous epithelium.  The change is benign and reversible to certain limit.
  • 8.  Adenoma – collection of growth (oma) f glandular origin. (may compress other structure or produce large amount of hormones. May become malignant called Adeno carcinoma.
  • 9.  Sarcoma –cancer that affects connective ,supportive and soft tisue (bone, cartilage, muscle or fat)  Osteosarcoma –bone  Chondrosarcoma –cartilage  Leiomyosarcoma –smooth muscle
  • 10.  Atrophy – shrinkage of cell size  Anaplasia – disorganized ,irregular cells that have loss of differentiation.(undifferentiated cells)  Metastasis –malignant cells travel through blood or lymph and invade other tissues and organs
  • 11.  Oncology –a branch of medicine that deals with tumor  Oncologist – a medical professional who practices oncology .