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Diabetic Drugs on Market or In Pipeline at July 6, 2011




                                                                                                                                                                   offshore approval
                                                                                                                under review


                                                                                                                                   on market


                                                                                                                                                   extension
                                                                                                Phase III
                                                                                 Phase II
                                                                   Phase I
   Company            drug or product       indication/substance
                Degludec                  t1 and t2 diabetes                 x              x               x
                DegludecPlus              t1 and t2 diabetes                 x              x               x
                Semaglutide               t2 diabetes                        x              x
                NN1953                    t1 and t2 diabetes                 x
                NN9068                    t2 diabetes                        x
                NN9924                    t2 diabetes                        x
 Novo Nordisk NovoLog Mix 70/30           insulin                                                                                              x
                NovoLog                   insulin                                                                                              x
                Levamir                   insulin                                                                                              x
                insulin pens              diabetes                                                                                             x
                Prandin                   t2 diabetes                                                                                          x
                Glucagen hypo kit         diabetes                                                                                             x
                Victoza                   t2 diabetes                                                                                          x
                Januvia                   t2 diabetes                                                                                          x
                Janumet                   t2 diabetes                                                                                          x
                MK3102                    diabetes mellitus                                 x
                MK0431C                   diabetes                                                          x
     Merck      MK0431A (sitagliptin/
                Extended-release
                metformin)                diabetes                                                                             x
                MK0431D
                sitagliptin/simvastatin   diabetes                                                                             x
                Kombiglyze™ XR/
                Onglyza™/metformin IR
                FDC#                      diabetes                                                                                                             x
                Dapagliflozin/metformin
                FDC#                      diabetes                                                                                                             x
 Astra Zeneca   Dapagliflozin             diabetes                                                          x
                AZD1656                   diabetes                           x              x
                AZD8329                   diabetes/obesity                   x              x
                AZD7687                   diabetes/obesity                   x              x
                AZD5658                   diabetes/obesity                   x              x
                saxagliptin               diabetes                                                                                             x
                Lyrica                    diabetic neuropathy                                                                                  x
     Pfizer     Lyrica                    neuropathic pain                                                                                                                             x
                Macugen                   diabetic macular edema                                                                                                                       x
                albiglutide               t2 diabetes                                                       x
                otelixizumab              t1 diabetes                        x                              x
GlaxoSmithKline albiglutide               t2 diabetes                                                       x
                1614235                   t2 diabetes                        x
                2245840                   t2 diabetes                                       x
                                          diabetic peripheral
                 Cymbalta                 neuropathic pain                                                                                     x
                 Humalog                  diabetes                                                                                             x
                 Humulin                  diabetes                                                                                             x
                 Byetta (w/Amylin)        t2 diabetes                                                                                          x
    Eli Lilly    Actos                    t2 diabetes                                                                                          x
                 BI10773                  diabetes                                                          x
                 GLP-1 Fc                 t2 diabetes                                                       x
                 Arxxant                  diabetic retinopathy                                                                 x
                 Linagliptin              diabetes                                                                             x
                 Avapro                   diabetic nephropathy                                                                                 x
 Bristol Myers   ONGLYZA                  diabetes                                                                                             x
    Squibb       KOMBIGLYZE               diabetes                                                                                             x
                 Dapagliflozin            diabetes                                                          x
                                          chronic kidney disease
    Abbott
                Bardoxolone methyl        and t2 diabetes                                                   x
                Byetta (w/Eli Lilly)      t2 diabetes                                                                                          x
    Amylin
                Symlin                    t2 diabetes                                                                                          x
Pharmaceuticals
                Bydureon                  t2 diabetes                                                                          x

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Diabetic drugs 7 6-11

  • 1. Diabetic Drugs on Market or In Pipeline at July 6, 2011 offshore approval under review on market extension Phase III Phase II Phase I Company drug or product indication/substance Degludec t1 and t2 diabetes x x x DegludecPlus t1 and t2 diabetes x x x Semaglutide t2 diabetes x x NN1953 t1 and t2 diabetes x NN9068 t2 diabetes x NN9924 t2 diabetes x Novo Nordisk NovoLog Mix 70/30 insulin x NovoLog insulin x Levamir insulin x insulin pens diabetes x Prandin t2 diabetes x Glucagen hypo kit diabetes x Victoza t2 diabetes x Januvia t2 diabetes x Janumet t2 diabetes x MK3102 diabetes mellitus x MK0431C diabetes x Merck MK0431A (sitagliptin/ Extended-release metformin) diabetes x MK0431D sitagliptin/simvastatin diabetes x Kombiglyze™ XR/ Onglyza™/metformin IR FDC# diabetes x Dapagliflozin/metformin FDC# diabetes x Astra Zeneca Dapagliflozin diabetes x AZD1656 diabetes x x AZD8329 diabetes/obesity x x AZD7687 diabetes/obesity x x AZD5658 diabetes/obesity x x saxagliptin diabetes x Lyrica diabetic neuropathy x Pfizer Lyrica neuropathic pain x Macugen diabetic macular edema x albiglutide t2 diabetes x otelixizumab t1 diabetes x x GlaxoSmithKline albiglutide t2 diabetes x 1614235 t2 diabetes x 2245840 t2 diabetes x diabetic peripheral Cymbalta neuropathic pain x Humalog diabetes x Humulin diabetes x Byetta (w/Amylin) t2 diabetes x Eli Lilly Actos t2 diabetes x BI10773 diabetes x GLP-1 Fc t2 diabetes x Arxxant diabetic retinopathy x Linagliptin diabetes x Avapro diabetic nephropathy x Bristol Myers ONGLYZA diabetes x Squibb KOMBIGLYZE diabetes x Dapagliflozin diabetes x chronic kidney disease Abbott Bardoxolone methyl and t2 diabetes x Byetta (w/Eli Lilly) t2 diabetes x Amylin Symlin t2 diabetes x Pharmaceuticals Bydureon t2 diabetes x