Please respond to this classmates post with a minimum of two paragra.docx

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Please respond to this classmates post with a minimum of two paragraphs, cited and app style. Two references no more than 5yrs old. Post: Urinary tract infections (UTIs) are among the most common infectious diseases occurring in either the community or healthcare setting. Uncomplicated UTIs typically occur in the healthy adult non-pregnant woman, while complicated UTIs (cUTIs) may occur in all sexes and age groups and are frequently associated with either structural or functional urinary tract abnormalities. Examples include foreign bodies such as calculi (stones), indwelling catheters or other drainage devices, obstruction, immunosuppression, renal failure, renal transplantation and pregnancy. UTI in the elderly is almost always complicated in men with prostatic hypertrophy and in post-menopausal women who may have an increased post-void residual volume. A urinary tract infection is an infection anywhere in the urinary tract. These often cause inflammation of the urethra (urethritis), bladder (cystitis), or kidneys (pyelonephritis).The symptoms depend on the area affected. Typical symptoms of a lower UTI include frequency and dysuria without fever, chills or back pain whereas upper UTI usually presents with symptoms of pyelonephritis such as loin pain, flank tenderness, fever or other signs of a systemic inflammatory response. Urinary tract infection is diagnosed by examination of a urine culture. Further investigations using intravenous urography or ultrasound scanning may be necessary. Most urinary tract infections are treated with antibiotic drugs. Increasing fluid intake and taking preparations such as potassium citrate that make the urine less acidic can relieve the symptoms. Trimethoprim/ sulfamethoxazole (Bactrim) Antibiotics—trimethoprim/ sulfamethoxazole (Bactrim) remains the first choice for community-acquired UTI in most areas. Complicated UTI is caused by a wider spectrum of organisms, and recommendations for treatment differ. Guidelines on specific antibiotic treatment and duration of treatment are available, but with increasing antibiotic resistance (including of E. coli to Trimethoprim), local microbiological advice should be taken into account when choosing antibiotic treatment. Advantages: Cheap, Well tolerated, high concentrations in vaginal and peri-urethral fluid. Possible reduced risk of emergence of resistant strains. Disadvantages: Increasing rates of resistance, adverse reactions (e.g. rash) to sulphonamide component. The efficacy of antibiotics is not fully predictable from in vitro sensitivity testing, which is probably part of the reason why trimethoprim (with or without sulphamethoxazole) remains the first-line choice in many areas, despite an upward trend in resistance rates. References: Scottish Intercollegiate Guidelines Network (2016). SIGN 88: Management of suspected bacterial urinary tract infections in adults. Dai B, et al. (2013). Long-term antibiotics for the prevention of recurrent urinar ...

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make the urine less acidic can relieve the symptoms.
Trimethoprim/ sulfamethoxazole (Bactrim)
Antibiotics—trimethoprim/ sulfamethoxazole (Bactrim) remains
the first choice for community-acquired UTI in most areas.
Complicated UTI is caused by a wider spectrum of organisms,
and recommendations for treatment differ. Guidelines on
specific antibiotic treatment and duration of treatment are
available, but with increasing antibiotic resistance (including of
E. coli to Trimethoprim), local microbiological advice should
be taken into account when choosing antibiotic treatment.
Advantages: Cheap, Well tolerated, high concentrations in
vaginal and peri-urethral fluid. Possible reduced risk of
emergence of resistant strains.
Disadvantages: Increasing rates of resistance, adverse reactions
(e.g. rash) to sulphonamide component.
The efficacy of antibiotics is not fully predictable from in vitro
sensitivity testing, which is probably part of the reason why
trimethoprim (with or without sulphamethoxazole) remains the
first-line choice in many areas, despite an upward trend in
resistance rates.
References:
Scottish Intercollegiate Guidelines Network (2016). SIGN 88:
Management of suspected bacterial urinary tract infections in
adults.
Dai B, et al. (2013). Long-term antibiotics for the prevention of
recurrent urinary tract infection in children: a systematic review
and meta-analysis. Arch Dis Child, 95, 499–508.

Wagenlehner FM, Naber KG, (2016). Treatment of bacterial
urinary tract infections: presence and future. Eur Urol, 49, 235–
44.[CrossRef] [Web of Science] [Medline]

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Respond on two different days who selected at least one different factor than you, in one or more of the following ways:Offer alternative diagnoses and prescription of treatment options for urinary tract infections.Share an insight from having read your colleague’s posting, synthesizing the information to provide new perspectives Main Post Urinary tract infections (UTI) are one of the most common infections in the world, and advanced practitioners must be able to diagnose and treat the varying types of UTIs. Understanding the location of the UTI, upper or lower, the pathophysiology, and specific signs and symptoms are crucial for treatment. An advanced practitioner must also be aware of the roles that gender and age play in the development of a UTI. UTIs are common in the outpatient setting but can also happen in the hospital and can also be caused by a Foley catheter, which is considered a hospital-acquired event that the hospital will not receive reimbursement. Pathophysiology of Lower Urinary Tract Infection A lower urinary tract infection involves the path of least resistance or the most opportunistic point of entry for an organism, usually bacterial and involves the urethra and the bladder. An infection in the urethra or bladder (cystitis) are considered a lower urinary tract infection. The microbial spectrum of UTIs consists mainly of Escherichia coli, with occasional other species of Enterobacteriaceae such as Proteus mirabilis and Klebsiella pneumoniae and other bacteria such as Staphylococcus saprophyticus (Yamamichi, Shigemura, Kitagawa, and Fujisawa, 2018). Pathophysiology of Upper Urinary Tract Infection The upper urinary tract consists of the kidneys and ureters. Infection in the upper urinary tract generally affects the kidneys (pyelonephritis), which can cause fever, chills, nausea, vomiting, and other severe symptoms. It can be caused by an infection that has made its way up the urinary tract and can become a complicated infection from an obstruction, such as benign prostatic hypertrophy, and calculi. Similarities and Differences Although the location of the infection is different many of the signs and symptoms can present the same; fever, dysuria, frequency, or urgency may be present in both. Many lower tract UTIs may be asymptomatic, and in upper tract UTIs, the symptoms may be more severe, including nausea and vomiting, flank pain, or costovertebral angle tenderness. Finding the underlying cause and treatment is the same; antibiotics for bacterial infections and analgesics for pain control. Intravenous antibiotics are preferred for upper tract UTIs in an attempt to preserve organ damage, but mat be converted to oral after initial treatment. Gender and Age as Factors While common in both males and females, females are more prone to community-acquired UTIs than men, basically because of anatomical differences. Lema (2015) ackno.

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