A hormonal disorder causing enlarged ovaries with small cysts on the outer edges. Women with PCOS often have increased levels of inflammation in their body. Being overweight can also contribute to inflammation. A short Presentation on what every doctor should know PCOS.

1. Dr. Laxmi Shrikhande
MD; FICOG; FICMCH;FICMU
 Director-Shrikhande Fertility Clinic, Nagpur
 Senior Vice President FOGSI 2012
 Associate member RCOG, London
 Member of European Society of Human Reproduction
 Received Bharat excellence Award for contribution to women’s health
 Chairperson HIV Committee FOGSI 2009-12
 Received best FOGSI committee award
 National Editor-The Journal of OB / GY of India
 Publications-Thirteen National & seven International
 Editor-FOGSI Focus on HIV in women
 Editor-FOGSI Focus on SUI- Myths & Facts
 Presented Papers at FIGO,SAFOG,AOFOG, IFFS

2. Dr Laxmi Shrikhande

3. • Dermatologist
• Cosmetologist
• Endocrinologist
• General Physician
• Gynecologist
• Bariatric Surgeon
• Dietician
• Gym trainers

4. • NIH (1990) – include all of the following
• Hyperandrogenism &/or hyperandrogenaemia
• Oligo-ovulation
• Exclusion of related disorders
• ESHRE/ASRM (Rotterdam 2003)- two of
the following
• Oligo or anovulation
• Clinical &/or biochemical signs of Hyperandrogenism
• Polycystic ovaries
• Androgen Excess Society (2006) - include
all of the following
• Hirsutism &/or hyperandrogenaemia
• Oligo – anovulation &/or polycystic ovaries
• Exclusion of androgen excess or related disorder

7. 1. Virilizing congenital adrenal hyperplasia
2. Cushing ’s syndrome
3. Virilizing tumors
4. Hyperprolactinemia
5. Insulin-resistance disorders
6. Acromegaly
7. Thyroid dysfunction
8. Drugs

8. • Most important goals
– Avoiding over- and under-diagnosis
– Counseling
– Prioritize specific aspects affecting health and
quality of life for each individual
– Minimize cardiometabolic sequelae

10. • Irregular menstruation
• Infertility -73% of anovulatory infertility Hull et al 87
•  risk of IGT / Type 2 diabetes
– Prevalence IGT x3 control
T2 DM x7 control Dahlgren et al 92
– IGT 35%, T2 DM 10% Ehrmann et al 99
IGT or DM at 40 yr old - 40% Legro 2001
– non-obese (14-44 yr old)
IGT 10.3% , DM 1.5% Legro et al 99
– Lean & *obese adolescent PCOS (13.9-19 yr old, 27 subjects)
IGT 30%, T2 DM 3.7% Palmert et al, JCEM, 2002

11. • Lipid abnormalities
– Sign lower HDL, higher total chol, LDL, TG Talbott et al 95
•  risk of CVS disease
–  risk factors for CVS disease
– subclinical athersclerotic disease
(greater carotid intimamedia wall thickness & coronary Ca++) Talbott et al 2001
– BUT no data on  prevalence of cardiovascular events
vs general population
•  risk of endometrial carcinoma
– Unopposed estrogen on endometrium

12. • Frequently seen in adolescence & young women
• Early diagnosis is important because of the
potential long-term consequences
• Primarily characterized by ovulatory
dysfunction & hyperandrogenism
• Diagnosis- USG abdomen showing polycystic
Ovaries and relevant blood tests

13. Management- Includes Non
pharmacological (weight
reduction, diet and exercise)
&
pharmacological (Combined OCPs
and Metformin)

14. “Anyone who stops learning is old,
whether at twenty or eighty. Anyone
who keeps learning stays young.”
― Henry Ford

15. My World of sharing
happiness!
Shrikhande IVF & Surrogacy
Center
Ph- 91 96234 59766
shrikhandedrlaxmi@gmail.com