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Constructing in vivo phosphorylation networks

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Lars Juhl Jensen
Lars Juhl Jensen

(Joint presentation with Rune Linding) 16th International Conference on Intelligent Systems for Molecular Biology, Metro Toronto Convention Centre, Toronto, Canada, July 19-23, 2008

TechnologyBusiness
1 of 40
NetPhorest
more sequence motifs
data organization
 
 
compilation of datasets
 
redundancy reduction
 
cross-validation partitioning
 
ANN training
classifier selection
 
an atlas of linear motifs
 
 
179 kinases
93 SH2 domains
8 PTB domains
BRCT domains
WW domains
14-3-3 proteins
benchmarking
relative scale
 
absolute scale
 
low-specificity kinases
disease-related kinases
 
docking domains
 
autophosphorylation
 
summary
 
Acknowledgments ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
 
Topics Network biology Signaling networks Association networks Disease systems biology Disease and drug networks Cell cycle and cancer Analysis of high-throughput data Protein interactions Phosphoproteomics Proteomics Transcriptomics Text mining Integration of text and high-throughput data

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